These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
222 related articles for article (PubMed ID: 25903124)
1. Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation. Rannversson H; Wilson P; Kristensen KB; Sinning S; Kristensen AS; Strømgaard K; Andersen J J Biol Chem; 2015 Jun; 290(23):14582-94. PubMed ID: 25903124 [TBL] [Abstract][Full Text] [Related]
2. Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding. Esendir E; Burtscher V; Coleman JA; Zhu R; Gouaux E; Freissmuth M; Sandtner W J Biol Chem; 2021 Jul; 297(1):100863. PubMed ID: 34118233 [TBL] [Abstract][Full Text] [Related]
3. Substrate and Inhibitor-Specific Conformational Changes in the Human Serotonin Transporter Revealed by Voltage-Clamp Fluorometry. Söderhielm PC; Andersen J; Munro L; Nielsen AT; Kristensen AS Mol Pharmacol; 2015 Oct; 88(4):676-88. PubMed ID: 26174773 [TBL] [Abstract][Full Text] [Related]
4. Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. Andersen J; Stuhr-Hansen N; Zachariassen L; Toubro S; Hansen SM; Eildal JN; Bond AD; Bøgesø KP; Bang-Andersen B; Kristensen AS; Strømgaard K Proc Natl Acad Sci U S A; 2011 Jul; 108(29):12137-42. PubMed ID: 21730142 [TBL] [Abstract][Full Text] [Related]
5. Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. Andersen J; Olsen L; Hansen KB; Taboureau O; Jørgensen FS; Jørgensen AM; Bang-Andersen B; Egebjerg J; Strømgaard K; Kristensen AS J Biol Chem; 2010 Jan; 285(3):2051-63. PubMed ID: 19892699 [TBL] [Abstract][Full Text] [Related]
6. Cholesterol binding to a conserved site modulates the conformation, pharmacology, and transport kinetics of the human serotonin transporter. Laursen L; Severinsen K; Kristensen KB; Periole X; Overby M; Müller HK; Schiøtt B; Sinning S J Biol Chem; 2018 Mar; 293(10):3510-3523. PubMed ID: 29352106 [TBL] [Abstract][Full Text] [Related]
7. A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin. Bjerregaard H; Severinsen K; Said S; Wiborg O; Sinning S J Biol Chem; 2015 Mar; 290(12):7747-55. PubMed ID: 25614630 [TBL] [Abstract][Full Text] [Related]
8. Identification of an allosteric modulator of the serotonin transporter with novel mechanism of action. Kortagere S; Fontana AC; Rose DR; Mortensen OV Neuropharmacology; 2013 Sep; 72():282-90. PubMed ID: 23632081 [TBL] [Abstract][Full Text] [Related]
9. Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Coleman JA; Yang D; Zhao Z; Wen PC; Yoshioka C; Tajkhorshid E; Gouaux E Nature; 2019 May; 569(7754):141-145. PubMed ID: 31019304 [TBL] [Abstract][Full Text] [Related]
10. Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket. Sørensen L; Andersen J; Thomsen M; Hansen SM; Zhao X; Sandelin A; Strømgaard K; Kristensen AS J Biol Chem; 2012 Dec; 287(52):43694-707. PubMed ID: 23086945 [TBL] [Abstract][Full Text] [Related]
11. The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle. Korkhov VM; Holy M; Freissmuth M; Sitte HH J Biol Chem; 2006 May; 281(19):13439-13448. PubMed ID: 16527819 [TBL] [Abstract][Full Text] [Related]
12. Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations. Gabrielsen M; Ravna AW; Kristiansen K; Sylte I J Mol Model; 2012 Mar; 18(3):1073-85. PubMed ID: 21670993 [TBL] [Abstract][Full Text] [Related]
13. Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol. Gabrielsen M; Kurczab R; Ravna AW; Kufareva I; Abagyan R; Chilmonczyk Z; Bojarski AJ; Sylte I Eur J Med Chem; 2012 Jan; 47(1):24-37. PubMed ID: 22071255 [TBL] [Abstract][Full Text] [Related]
14. The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter. Plenge P; Abramyan AM; Sørensen G; Mørk A; Weikop P; Gether U; Bang-Andersen B; Shi L; Loland CJ Nat Commun; 2020 Mar; 11(1):1491. PubMed ID: 32198394 [TBL] [Abstract][Full Text] [Related]
15. Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands. Andersen J; Ladefoged LK; Kristensen TN; Munro L; Grouleff J; Stuhr-Hansen N; Kristensen AS; Schiøtt B; Strømgaard K ACS Chem Neurosci; 2016 Oct; 7(10):1406-1417. PubMed ID: 27425420 [TBL] [Abstract][Full Text] [Related]
16. Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation. Larsen MB; Sonders MS; Mortensen OV; Larson GA; Zahniser NR; Amara SG J Neurosci; 2011 Apr; 31(17):6605-15. PubMed ID: 21525301 [TBL] [Abstract][Full Text] [Related]
17. The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. Plenge P; Yang D; Salomon K; Laursen L; Kalenderoglou IE; Newman AH; Gouaux E; Coleman JA; Loland CJ Nat Commun; 2021 Aug; 12(1):5063. PubMed ID: 34417466 [TBL] [Abstract][Full Text] [Related]
18. Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the 5-HT transporter. Larsen MA; Plenge P; Andersen J; Eildal JN; Kristensen AS; Bøgesø KP; Gether U; Strømgaard K; Bang-Andersen B; Loland CJ Br J Pharmacol; 2016 Mar; 173(5):925-36. PubMed ID: 26699847 [TBL] [Abstract][Full Text] [Related]
19. The N terminus of monoamine transporters is a lever required for the action of amphetamines. Sucic S; Dallinger S; Zdrazil B; Weissensteiner R; Jørgensen TN; Holy M; Kudlacek O; Seidel S; Cha JH; Gether U; Newman AH; Ecker GF; Freissmuth M; Sitte HH J Biol Chem; 2010 Apr; 285(14):10924-38. PubMed ID: 20118234 [TBL] [Abstract][Full Text] [Related]
20. High- and low-affinity binding of S-citalopram to the human serotonin transporter mutated at 20 putatively important amino acid positions. Plenge P; Wiborg O Neurosci Lett; 2005 Aug; 383(3):203-8. PubMed ID: 15955412 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]