654 related articles for article (PubMed ID: 25904760)
1. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.
Lee B; Ji HK; Lee T; Liu KH
Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760
[TBL] [Abstract][Full Text] [Related]
2. Screening of ten cytochrome P450 enzyme activities with 12 probe substrates in human liver microsomes using cocktail incubation and liquid chromatography-tandem mass spectrometry.
Kim HJ; Lee H; Ji HK; Lee T; Liu KH
Biopharm Drug Dispos; 2019 Apr; 40(3-4):101-111. PubMed ID: 30730576
[TBL] [Abstract][Full Text] [Related]
3. In vitro assay of six UDP-glucuronosyltransferase isoforms in human liver microsomes, using cocktails of probe substrates and liquid chromatography-tandem mass spectrometry.
Seo KA; Kim HJ; Jeong ES; Abdalla N; Choi CS; Kim DH; Shin JG
Drug Metab Dispos; 2014 Nov; 42(11):1803-10. PubMed ID: 25122565
[TBL] [Abstract][Full Text] [Related]
4. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
Liu LY; Han YL; Zhu JH; Yu Q; Yang QJ; Lu J; Guo C
Biomed Chromatogr; 2015 Mar; 29(3):437-44. PubMed ID: 25098274
[TBL] [Abstract][Full Text] [Related]
5. High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.
Kim MJ; Kim H; Cha IJ; Park JS; Shon JH; Liu KH; Shin JG
Rapid Commun Mass Spectrom; 2005; 19(18):2651-8. PubMed ID: 16124035
[TBL] [Abstract][Full Text] [Related]
6. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
Kim JH; Kwon SS; Kong TY; Cheong JC; Kim HS; In MK; Lee HS
Molecules; 2017 Mar; 22(3):. PubMed ID: 28287454
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.
Liu S; Wang Z; Chan E; Zhao Y; Kang J; Zhang X; Tian X
Chem Biol Interact; 2022 Jan; 352():109775. PubMed ID: 34910929
[TBL] [Abstract][Full Text] [Related]
8. Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
Kwon SS; Kim JH; Jeong HU; Cho YY; Oh SR; Lee HS
Molecules; 2016 Apr; 21(5):. PubMed ID: 27128896
[TBL] [Abstract][Full Text] [Related]
9. Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats.
Zhang S; Song N; Li Q; Fan H; Liu C
J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Aug; 871(1):78-89. PubMed ID: 18614408
[TBL] [Abstract][Full Text] [Related]
10. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.
Walsky RL; Bauman JN; Bourcier K; Giddens G; Lapham K; Negahban A; Ryder TF; Obach RS; Hyland R; Goosen TC
Drug Metab Dispos; 2012 May; 40(5):1051-65. PubMed ID: 22357286
[TBL] [Abstract][Full Text] [Related]
11. A comprehensive assay for nine major cytochrome P450 enzymes activities with 16 probe reactions on human liver microsomes by a single LC/MS/MS run to support reliable in vitro inhibitory drug-drug interaction evaluation.
Peng Y; Wu H; Zhang X; Zhang F; Qi H; Zhong Y; Wang Y; Sang H; Wang G; Sun J
Xenobiotica; 2015; 45(11):961-77. PubMed ID: 26007223
[TBL] [Abstract][Full Text] [Related]
12. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
Chen A; Zhou X; Cheng Y; Tang S; Liu M; Wang X
Toxicol Lett; 2018 Oct; 295():379-389. PubMed ID: 30036684
[TBL] [Abstract][Full Text] [Related]
13. Screening of six UGT enzyme activities in human liver microsomes using liquid chromatography/triple quadrupole mass spectrometry.
Joo J; Lee B; Lee T; Liu KH
Rapid Commun Mass Spectrom; 2014 Nov; 28(22):2405-14. PubMed ID: 25303469
[TBL] [Abstract][Full Text] [Related]
14. Direct and metabolism-dependent cytochrome P450 inhibition assays for evaluating drug-drug interactions.
Lee KS; Kim SK
J Appl Toxicol; 2013 Feb; 33(2):100-8. PubMed ID: 21915887
[TBL] [Abstract][Full Text] [Related]
15. A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.
Dierks EA; Stams KR; Lim HK; Cornelius G; Zhang H; Ball SE
Drug Metab Dispos; 2001 Jan; 29(1):23-9. PubMed ID: 11124225
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.
Zheng YF; Bae SH; Choi EJ; Park JB; Kim SO; Jang MJ; Park GH; Shin WG; Oh E; Bae SK
Food Chem Toxicol; 2014 Jun; 68():117-27. PubMed ID: 24632066
[TBL] [Abstract][Full Text] [Related]
17. An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point.
Youdim KA; Lyons R; Payne L; Jones BC; Saunders K
J Pharm Biomed Anal; 2008 Sep; 48(1):92-9. PubMed ID: 18584988
[TBL] [Abstract][Full Text] [Related]
18. An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.
Otten JN; Hingorani GP; Hartley DP; Kragerud SD; Franklin RB
Drug Metab Lett; 2011 Jan; 5(1):17-24. PubMed ID: 21198441
[TBL] [Abstract][Full Text] [Related]
19. Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse.
Dinger J; Meyer MR; Maurer HH
Toxicol Lett; 2014 Oct; 230(1):28-35. PubMed ID: 25111188
[TBL] [Abstract][Full Text] [Related]
20. Validated liquid chromatography-tandem mass spectrometry method for determination of totally nine probe metabolites of cytochrome P450 enzymes and UDP-glucuronosyltransferases.
Lee JT; Pao LH; Hsiong CH; Huang PW; Shih TY; Yoa-Pu Hu O
Talanta; 2013 Mar; 106():220-8. PubMed ID: 23598120
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
