BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 25907366)

  • 1. Discovery of oxime-bearing naphthalene derivatives as a novel structural type of Nrf2 activators.
    Chang KM; Liang FP; Chen IL; Yang SC; Juang SH; Wang TC; Chen YL; Tzeng CC
    Bioorg Med Chem; 2015 Jul; 23(13):3852-9. PubMed ID: 25907366
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model.
    Chang KM; Chen HH; Wang TC; Chen IL; Chen YT; Yang SC; Chen YL; Chang HH; Huang CH; Chang JY; Shih C; Kuo CC; Tzeng CC
    Eur J Med Chem; 2015 Dec; 106():60-74. PubMed ID: 26519930
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.
    Giudice A; Arra C; Turco MC
    Methods Mol Biol; 2010; 647():37-74. PubMed ID: 20694660
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties.
    Dai H; Jiao Q; Liu T; You Q; Jiang Z
    Molecules; 2017 Sep; 22(9):. PubMed ID: 28902165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protolichesterinic acid derivatives: α-methylene-γ-lactones as potent dual activators of PPARγ and Nrf2 transcriptional factors.
    Le Lamer AC; Authier H; Rouaud I; Coste A; Boustie J; Pipy B; Gouault N
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3819-22. PubMed ID: 25027935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the Nrf2-regulated antioxidant cell response inhibits HEMA-induced oxidative stress and supports cell viability.
    Gallorini M; Petzel C; Bolay C; Hiller KA; Cataldi A; Buchalla W; Krifka S; Schweikl H
    Biomaterials; 2015 Jul; 56():114-28. PubMed ID: 25934285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The nuclear matrix protein, NRP/B, enhances Nrf2-mediated oxidative stress responses in breast cancer cells.
    Seng S; Avraham HK; Jiang S; Yang S; Sekine M; Kimelman N; Li H; Avraham S
    Cancer Res; 2007 Sep; 67(18):8596-604. PubMed ID: 17875699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of novel alkannin and shikonin oxime derivatives as potent antitumor agents.
    Wang R; Zhang X; Song H; Zhou S; Li S
    Bioorg Med Chem Lett; 2014 Sep; 24(17):4304-7. PubMed ID: 25127868
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antiproliferative activity of some androstene oximes and their O-alkylated derivatives.
    Acharya PC; Bansal R
    Arch Pharm (Weinheim); 2014 Mar; 347(3):193-9. PubMed ID: 24343881
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression.
    Boettler U; Sommerfeld K; Volz N; Pahlke G; Teller N; Somoza V; Lang R; Hofmann T; Marko D
    J Nutr Biochem; 2011 May; 22(5):426-40. PubMed ID: 20655719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of the Nrf2 signalling pathway in Hct116 colon carcinoma cells by baicalein and its methylated derivative negletein.
    Havermann S; Chovolou Y; Humpf HU; Wätjen W
    Pharm Biol; 2016 Sep; 54(9):1491-502. PubMed ID: 27143122
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Nrf2 as a chemoprevention target in gastrointestinal carcinoma].
    Gao P; Tang XW; Wang XJ
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2012 Jul; 41(4):453-63. PubMed ID: 22927084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel kavalactone derivative protects against H2O2-induced PC12 cell death via Nrf2/ARE activation.
    Tanaka A; Hamada N; Fujita Y; Itoh T; Nozawa Y; Iinuma M; Ito M
    Bioorg Med Chem; 2010 May; 18(9):3133-9. PubMed ID: 20371185
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of nrf2 by cancer chemotherapeutic agents.
    Wang XJ; Hayes JD; Wolf CR
    Cancer Res; 2006 Nov; 66(22):10983-94. PubMed ID: 17108137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and bioevaluation of a series of α-pyrone derivatives as potent activators of Nrf2/ARE pathway (part I).
    Xi MY; Sun ZY; Sun HP; Jia JM; Jiang ZY; Tao L; Ye M; Yang X; Wang YJ; Xue X; Huang JJ; Gao Y; Guo XK; Zhang SL; Yang YR; Guo QL; Hu R; You QD
    Eur J Med Chem; 2013 Aug; 66():364-71. PubMed ID: 23820128
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Monascin and AITC attenuate methylglyoxal-induced PPARγ phosphorylation and degradation through inhibition of the oxidative stress/PKC pathway depending on Nrf2 activation.
    Hsu WH; Lee BH; Li CH; Hsu YW; Pan TM
    J Agric Food Chem; 2013 Jun; 61(25):5996-6006. PubMed ID: 23731245
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators.
    Jain AD; Potteti H; Richardson BG; Kingsley L; Luciano JP; Ryuzoji AF; Lee H; Krunic A; Mesecar AD; Reddy SP; Moore TW
    Eur J Med Chem; 2015 Oct; 103():252-68. PubMed ID: 26363505
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship Study.
    Xu LL; Zhu JF; Xu XL; Zhu J; Li L; Xi MY; Jiang ZY; Zhang MY; Liu F; Lu MC; Bao QC; Li Q; Zhang C; Wei JL; Zhang XJ; Zhang LS; You QD; Sun HP
    J Med Chem; 2015 Jul; 58(14):5419-36. PubMed ID: 26111355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents.
    Milelli A; Tumiatti V; Micco M; Rosini M; Zuccari G; Raffaghello L; Bianchi G; Pistoia V; Fernando Díaz J; Pera B; Trigili C; Barasoain I; Musetti C; Toniolo M; Sissi C; Alcaro S; Moraca F; Zini M; Stefanelli C; Minarini A
    Eur J Med Chem; 2012 Nov; 57():417-28. PubMed ID: 22819507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and synthesis of sulfur-containing 6-substituted 5,8-dimethoxy-1,4-naphthoquinone oxime derivatives as new and potential anti-MDR cancer agents.
    Huang G; Dong JY; Zhang QJ; Meng QQ; Zhao HR; Zhu BQ; Li SS
    Eur J Med Chem; 2019 Mar; 165():160-171. PubMed ID: 30677614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.