BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

525 related articles for article (PubMed ID: 25908246)

  • 1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration.
    Liu H; Yu N; Lu S; Ito S; Zhang X; Prasad B; He E; Lu X; Li Y; Wang F; Xu H; An G; Unadkat JD; Kusuhara H; Sugiyama Y; Sahi J
    Drug Metab Dispos; 2015 Jul; 43(7):1008-18. PubMed ID: 25908246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hydrophilic anti-migraine triptans are substrates for OATP1A2, a transporter expressed at human blood-brain barrier.
    Cheng Z; Liu H; Yu N; Wang F; An G; Xu Y; Liu Q; Guan CB; Ayrton A
    Xenobiotica; 2012 Sep; 42(9):880-90. PubMed ID: 22509823
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.
    Ose A; Kusuhara H; Endo C; Tohyama K; Miyajima M; Kitamura S; Sugiyama Y
    Drug Metab Dispos; 2010 Jan; 38(1):168-76. PubMed ID: 19833843
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier.
    Sano Y; Mizuno T; Mochizuki T; Uchida Y; Umetsu M; Terasaki T; Kusuhara H
    Drug Metab Dispos; 2018 Nov; 46(11):1767-1775. PubMed ID: 30154106
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1.
    Qi X; Wagenaar E; Xu W; Huang K; Schinkel AH
    Toxicol Appl Pharmacol; 2017 Aug; 329():18-25. PubMed ID: 28532671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor-
    Ronaldson PT; Brzica H; Abdullahi W; Reilly BG; Davis TP
    J Pharmacol Exp Ther; 2021 Feb; 376(2):148-160. PubMed ID: 33168642
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of β-blockers and tricyclic antidepressants on the activity of human organic anion transporting polypeptide 1A2 (OATP1A2).
    Lu J; Michaud V; Moya LG; Gaudette F; Leung YH; Turgeon J
    J Pharmacol Exp Ther; 2015 Mar; 352(3):552-8. PubMed ID: 25563901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic polymorphisms and function of the organic anion-transporting polypeptide 1A2 and its clinical relevance in drug disposition.
    Zhou Y; Yuan J; Li Z; Wang Z; Cheng D; Du Y; Li W; Kan Q; Zhang W
    Pharmacology; 2015; 95(3-4):201-8. PubMed ID: 25924632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.
    Lee HH; Leake BF; Kim RB; Ho RH
    Mol Pharmacol; 2017 Jan; 91(1):14-24. PubMed ID: 27777271
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy.
    Hubeny A; Keiser M; Oswald S; Jedlitschky G; Kroemer HK; Siegmund W; Grube M
    Drug Metab Dispos; 2016 Oct; 44(10):1562-8. PubMed ID: 27504015
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1.
    Mandery K; Bujok K; Schmidt I; Keiser M; Siegmund W; Balk B; König J; Fromm MF; Glaeser H
    Biochem Pharmacol; 2010 Dec; 80(11):1746-53. PubMed ID: 20797388
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption.
    Shitara Y; Maeda K; Ikejiri K; Yoshida K; Horie T; Sugiyama Y
    Biopharm Drug Dispos; 2013 Jan; 34(1):45-78. PubMed ID: 23115084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.
    Taub ME; Mease K; Sane RS; Watson CA; Chen L; Ellens H; Hirakawa B; Reyner EL; Jani M; Lee CA
    Drug Metab Dispos; 2011 Nov; 39(11):2093-102. PubMed ID: 21849517
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein.
    Liu H; Huang L; Li Y; Fu T; Sun X; Zhang YY; Gao R; Chen Q; Zhang W; Sahi J; Summerfield S; Dong K
    Drug Metab Dispos; 2017 May; 45(5):449-456. PubMed ID: 28209803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intestinal drug transporter expression and the impact of grapefruit juice in humans.
    Glaeser H; Bailey DG; Dresser GK; Gregor JC; Schwarz UI; McGrath JS; Jolicoeur E; Lee W; Leake BF; Tirona RG; Kim RB
    Clin Pharmacol Ther; 2007 Mar; 81(3):362-70. PubMed ID: 17215845
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular Mechanisms of Organic Anion Transporting Polypeptide-Mediated Organic Anion Clearance at the Blood-Cerebrospinal Fluid Barrier.
    Sun A; Hagenbuch B; Kelly EJ; Wang J
    Mol Pharmacol; 2023 Dec; 104(6):255-265. PubMed ID: 37652713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood-Brain Barrier in Glioblastoma Patients Using an IVIVE-PBPK Modeling Approach.
    Li J; Wu J; Bao X; Honea N; Xie Y; Kim S; Sparreboom A; Sanai N
    Clin Cancer Res; 2017 Dec; 23(24):7454-7466. PubMed ID: 28928160
    [No Abstract]   [Full Text] [Related]  

  • 18. Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS.
    Gao B; Vavricka SR; Meier PJ; Stieger B
    Pflugers Arch; 2015 Jul; 467(7):1481-1493. PubMed ID: 25132355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta.
    Tupova L; Hirschmugl B; Sucha S; Pilarova V; Székely V; Bakos É; Novakova L; Özvegy-Laczka C; Wadsack C; Ceckova M
    Biomed Pharmacother; 2020 Sep; 129():110506. PubMed ID: 32768979
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.
    Ming X; Knight BM; Thakker DR
    Mol Pharm; 2011 Oct; 8(5):1677-86. PubMed ID: 21780830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.