BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 25909884)

  • 1. Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.
    Wree A; Johnson CD; Font-Burgada J; Eguchi A; Povero D; Karin M; Feldstein AE
    Cell Death Differ; 2015 Dec; 22(12):1985-94. PubMed ID: 25909884
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
    Liang S; Ma HY; Zhong Z; Dhar D; Liu X; Xu J; Koyama Y; Nishio T; Karin D; Karin G; Mccubbin R; Zhang C; Hu R; Yang G; Chen L; Ganguly S; Lan T; Karin M; Kisseleva T; Brenner DA
    Gastroenterology; 2019 Mar; 156(4):1156-1172.e6. PubMed ID: 30445007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
    Nozaki Y; Hikita H; Tanaka S; Fukumoto K; Urabe M; Sato K; Myojin Y; Doi A; Murai K; Sakane S; Saito Y; Kodama T; Sakamori R; Tatsumi T; Takehara T
    Sci Rep; 2021 Feb; 11(1):3363. PubMed ID: 33564095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Liver-specific Bid silencing inhibits APAP-induced cell death in mice.
    Maxa M; Schaeper U; Dames S; Vollmar B; Kuhla A
    Apoptosis; 2019 Dec; 24(11-12):934-945. PubMed ID: 31576482
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bid-independent mitochondrial activation in tumor necrosis factor alpha-induced apoptosis and liver injury.
    Chen X; Ding WX; Ni HM; Gao W; Shi YH; Gambotto AA; Fan J; Beg AA; Yin XM
    Mol Cell Biol; 2007 Jan; 27(2):541-53. PubMed ID: 17101783
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice.
    Ni HM; Chen X; Shi YH; Liao Y; Beg AA; Fan J; Yin XM
    J Biol Chem; 2009 Feb; 284(7):4373-82. PubMed ID: 19060338
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
    Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T
    J Biol Chem; 2013 Oct; 288(42):30009-30018. PubMed ID: 23986435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation.
    Sakurai T; Maeda S; Chang L; Karin M
    Proc Natl Acad Sci U S A; 2006 Jul; 103(28):10544-51. PubMed ID: 16807293
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Liver Bid suppression for treatment of fibrosis associated with non-alcoholic steatohepatitis.
    Eguchi A; De Mollerat Du Jeu X; Johnson CD; Nektaria A; Feldstein AE
    J Hepatol; 2016 Mar; 64(3):699-707. PubMed ID: 26555271
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dihydromyricetin alleviates carbon tetrachloride-induced acute liver injury via JNK-dependent mechanism in mice.
    Xie J; Liu J; Chen TM; Lan Q; Zhang QY; Liu B; Dai D; Zhang WD; Hu LP; Zhu RZ
    World J Gastroenterol; 2015 May; 21(18):5473-81. PubMed ID: 25987769
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phycocyanobilin accelerates liver regeneration and reduces mortality rate in carbon tetrachloride-induced liver injury mice.
    Liu J; Zhang QY; Yu LM; Liu B; Li MY; Zhu RZ
    World J Gastroenterol; 2015 May; 21(18):5465-72. PubMed ID: 25987768
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.
    Maeda S; Kamata H; Luo JL; Leffert H; Karin M
    Cell; 2005 Jul; 121(7):977-90. PubMed ID: 15989949
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of sex and developmental stage on acute hepatotoxic and inflammatory responses to liver procarcinogens in the mouse.
    Hanna D; Riedmaier AE; Sugamori KS; Grant DM
    Toxicology; 2016 Dec; 373():30-40. PubMed ID: 27746196
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation.
    Roychowdhury S; Chiang DJ; Mandal P; McMullen MR; Liu X; Cohen JI; Pollard J; Feldstein AE; Nagy LE
    Alcohol Clin Exp Res; 2012 Jul; 36(7):1139-47. PubMed ID: 22273278
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
    Lin YH; Zhang S; Zhu M; Lu T; Chen K; Wen Z; Wang S; Xiao G; Luo D; Jia Y; Li L; MacConmara M; Hoshida Y; Singal AG; Yopp A; Wang T; Zhu H
    Gastroenterology; 2020 May; 158(6):1698-1712.e14. PubMed ID: 31972235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thromboxane A(2) receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment.
    Minamino T; Ito Y; Ohkubo H; Hosono K; Suzuki T; Sato T; Ae T; Shibuya A; Sakagami H; Narumiya S; Koizumi W; Majima M
    Toxicol Appl Pharmacol; 2012 Feb; 259(1):104-14. PubMed ID: 22206755
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice.
    Lazic M; Eguchi A; Berk MP; Povero D; Papouchado B; Mulya A; Johnson CD; Feldstein AE
    J Hepatol; 2014 Jul; 61(1):107-15. PubMed ID: 24681344
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the Mitochondrial Apoptotic Pathway Produces Reactive Oxygen Species and Oxidative Damage in Hepatocytes That Contribute to Liver Tumorigenesis.
    Hikita H; Kodama T; Tanaka S; Saito Y; Nozaki Y; Nakabori T; Shimizu S; Hayashi Y; Li W; Shigekawa M; Sakamori R; Miyagi T; Hiramatsu N; Tatsumi T; Takehara T
    Cancer Prev Res (Phila); 2015 Aug; 8(8):693-701. PubMed ID: 26038117
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene Expression Analysis Indicates Divergent Mechanisms in DEN-Induced Carcinogenesis in Wild Type and Bid-Deficient Livers.
    Yu C; Yan S; Khambu B; Chen X; Dong Z; Luo J; Michalopoulos GK; Wu S; Yin XM
    PLoS One; 2016; 11(5):e0155211. PubMed ID: 27196317
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation.
    Wu Q; Chen JX; Chen Y; Cai LL; Wang XZ; Guo WH; Zheng JF
    Cell Death Dis; 2018 Feb; 9(2):232. PubMed ID: 29445190
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.