BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 25910219)

  • 1. Fibril Core of Transforming Growth Factor Beta-Induced Protein (TGFBIp) Facilitates Aggregation of Corneal TGFBIp.
    Sørensen CS; Runager K; Scavenius C; Jensen MM; Nielsen NS; Christiansen G; Petersen SV; Karring H; Sanggaard KW; Enghild JJ
    Biochemistry; 2015 May; 54(19):2943-56. PubMed ID: 25910219
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits.
    Karring H; Poulsen ET; Runager K; Thøgersen IB; Klintworth GK; Højrup P; Enghild JJ
    Mol Vis; 2013; 19():861-76. PubMed ID: 23592924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene.
    Karring H; Runager K; Thøgersen IB; Klintworth GK; Højrup P; Enghild JJ
    Exp Eye Res; 2012 Mar; 96(1):163-70. PubMed ID: 22155582
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.
    Andreasen M; Nielsen SB; Runager K; Christiansen G; Nielsen NC; Enghild JJ; Otzen DE
    J Biol Chem; 2012 Oct; 287(41):34730-42. PubMed ID: 22893702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization.
    Underhaug J; Koldsø H; Runager K; Nielsen JT; Sørensen CS; Kristensen T; Otzen DE; Karring H; Malmendal A; Schiøtt B; Enghild JJ; Nielsen NC
    Biochim Biophys Acta; 2013 Dec; 1834(12):2812-22. PubMed ID: 24129074
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp.
    Runager K; Basaiawmoit RV; Deva T; Andreasen M; Valnickova Z; Sørensen CS; Karring H; Thøgersen IB; Christiansen G; Underhaug J; Kristensen T; Nielsen NC; Klintworth GK; Otzen DE; Enghild JJ
    J Biol Chem; 2011 Feb; 286(7):4951-8. PubMed ID: 21135107
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epigallocatechin Gallate Remodels Fibrils of Lattice Corneal Dystrophy Protein, Facilitating Proteolytic Degradation and Preventing Formation of Membrane-Permeabilizing Species.
    Stenvang M; Christiansen G; Otzen DE
    Biochemistry; 2016 Apr; 55(16):2344-57. PubMed ID: 27042751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene.
    Poulsen ET; Runager K; Risør MW; Dyrlund TF; Scavenius C; Karring H; Praetorius J; Vorum H; Otzen DE; Klintworth GK; Enghild JJ
    Proteomics Clin Appl; 2014 Apr; 8(3-4):168-77. PubMed ID: 24302499
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation-Induced Deamidation of Corneal Dystrophy-Related Transforming Growth Factor β-Induced Protein.
    Nielsen NS; Juhl DW; Poulsen ET; Lukassen MV; Poulsen EC; Risør MW; Scavenius C; Enghild JJ
    Biochemistry; 2017 Dec; 56(49):6470-6480. PubMed ID: 29140698
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Early Events in the Amyloid Formation of the A546T Mutant of Transforming Growth Factor β-Induced Protein in Corneal Dystrophies Compared to the Nonfibrillating R555W and R555Q Mutants.
    Koldsø H; Andersen OJ; Nikolajsen CL; Scavenius C; Sørensen CS; Underhaug J; Runager K; Nielsen NC; Enghild JJ; Schiøtt B
    Biochemistry; 2015 Sep; 54(36):5546-56. PubMed ID: 26305369
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.
    Poulsen ET; Nielsen NS; Scavenius C; Mogensen EH; Risør MW; Runager K; Lukassen MV; Rasmussen CB; Christiansen G; Richner M; Vorum H; Enghild JJ
    J Biol Chem; 2019 Aug; 294(31):11817-11828. PubMed ID: 31197037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.
    García-Castellanos R; Nielsen NS; Runager K; Thøgersen IB; Lukassen MV; Poulsen ET; Goulas T; Enghild JJ; Gomis-Rüth FX
    Structure; 2017 Nov; 25(11):1740-1750.e2. PubMed ID: 28988748
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients.
    Anandalakshmi V; Murugan E; Leng EGT; Ting LW; Chaurasia SS; Yamazaki T; Nagashima T; George BL; Peh GSL; Pervushin K; Lakshminarayanan R; Mehta JS
    Biochem J; 2017 May; 474(10):1705-1725. PubMed ID: 28381645
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Near-complete 1H, 13C, 15N resonance assignments of dimethylsulfoxide-denatured TGFBIp FAS1-4 A546T.
    Kulminskaya NV; Yoshimura Y; Runager K; Sørensen CS; Bjerring M; Andreasen M; Otzen DE; Enghild JJ; Nielsen NC; Mulder FA
    Biomol NMR Assign; 2016 Apr; 10(1):25-9. PubMed ID: 26275916
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies.
    Nielsen NS; Poulsen ET; Lukassen MV; Chao Shern C; Mogensen EH; Weberskov CE; DeDionisio L; Schauser L; Moore TCB; Otzen DE; Hjortdal J; Enghild JJ
    Prog Retin Eye Res; 2020 Jul; 77():100843. PubMed ID: 32004730
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmaceutical modulation of the proteolytic profile of Transforming Growth Factor Beta induced protein (TGFBIp) offers a new avenue for treatment of
    Venkatraman A; Duong-Thi MD; Pervushin K; Ohlson S; Mehta JS
    J Adv Res; 2020 Jul; 24():529-543. PubMed ID: 32637173
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SAXS models of TGFBIp reveal a trimeric structure and show that the overall shape is not affected by the Arg124His mutation.
    Basaiawmoit RV; Oliveira CL; Runager K; Sørensen CS; Behrens MA; Jonsson BH; Kristensen T; Klintworth GK; Enghild JJ; Pedersen JS; Otzen DE
    J Mol Biol; 2011 May; 408(3):503-13. PubMed ID: 21371477
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein Composition of TGFBI-R124C- and TGFBI-R555W-Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy.
    Courtney DG; Poulsen ET; Kennedy S; Moore JE; Atkinson SD; Maurizi E; Nesbit MA; Moore CB; Enghild JJ
    Invest Ophthalmol Vis Sci; 2015 Jul; 56(8):4653-61. PubMed ID: 26207300
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.
    Patel DA; Chang SH; Harocopos GJ; Vora SC; Thang DH; Huang AJ
    Cornea; 2010 Nov; 29(11):1215-22. PubMed ID: 20697279
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).
    Poulsen ET; Nielsen NS; Jensen MM; Nielsen E; Hjortdal J; Kim EK; Enghild JJ
    Proteomics; 2016 Feb; 16(3):539-43. PubMed ID: 26864644
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.