BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 25910237)

  • 21. Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitors.
    Zuo M; Zheng YW; Lu SM; Li Y; Zhang SQ
    Bioorg Med Chem; 2012 Jul; 20(14):4405-12. PubMed ID: 22698782
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif.
    Wagner FF; Olson DE; Gale JP; Kaya T; Weïwer M; Aidoud N; Thomas M; Davoine EL; Lemercier BC; Zhang YL; Holson EB
    J Med Chem; 2013 Feb; 56(4):1772-6. PubMed ID: 23368884
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, synthesis, and biological activity of hydroxamic tertiary amines as histone deacetylase inhibitors.
    Terracciano S; Chini MG; Riccio R; Bruno I; Bifulco G
    ChemMedChem; 2012 Apr; 7(4):694-702. PubMed ID: 22278987
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design and synthesis of novel and highly-active pan-histone deacetylase (pan-HDAC) inhibitors.
    Tashima T; Murata H; Kodama H
    Bioorg Med Chem; 2014 Jul; 22(14):3720-31. PubMed ID: 24864038
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors.
    Huang WJ; Chen CC; Chao SW; Yu CC; Yang CY; Guh JH; Lin YC; Kuo CI; Yang P; Chang CI
    Eur J Med Chem; 2011 Sep; 46(9):4042-9. PubMed ID: 21712146
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The discovery of colchicine-SAHA hybrids as a new class of antitumor agents.
    Zhang X; Zhang J; Tong L; Luo Y; Su M; Zang Y; Li J; Lu W; Chen Y
    Bioorg Med Chem; 2013 Jun; 21(11):3240-4. PubMed ID: 23602523
    [TBL] [Abstract][Full Text] [Related]  

  • 27. [New synthesis of highly selective inhibitor of histone deacetylase 6--N-hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3b]indol-5-ylmethyl)benzamide--Tubastatin A].
    Kozlov MV; Kleĭmenova AA; Konduktorov KA; Kochetkov SN
    Bioorg Khim; 2013; 39(1):117-20. PubMed ID: 23844513
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Perfluorinated hydroxamic acids are potent and selective inhibitors of HDAC-like enzymes from Pseudomonas aeruginosa.
    Meyners C; Wolff B; Kleinschek A; Krämer A; Meyer-Almes FJ
    Bioorg Med Chem Lett; 2017 Apr; 27(7):1508-1512. PubMed ID: 28259626
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Functional differences in epigenetic modulators-superiority of mercaptoacetamide-based histone deacetylase inhibitors relative to hydroxamates in cortical neuron neuroprotection studies.
    Kozikowski AP; Chen Y; Gaysin A; Chen B; D'Annibale MA; Suto CM; Langley BC
    J Med Chem; 2007 Jun; 50(13):3054-61. PubMed ID: 17539623
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors.
    Thaler F; Varasi M; Colombo A; Boggio R; Munari D; Regalia N; Rozio MG; Reali V; Resconi AE; Mai A; Gagliardi S; Dondio G; Minucci S; Mercurio C
    ChemMedChem; 2010 Aug; 5(8):1359-72. PubMed ID: 20572281
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The structural requirements of histone deacetylase inhibitors: SAHA analogs modified at the C5 position display dual HDAC6/8 selectivity.
    Negmeldin AT; Pflum MKH
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3254-3258. PubMed ID: 28648461
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors.
    Zhou M; Ning C; Liu R; He Y; Yu N
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3200-3. PubMed ID: 23639537
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A structure-based virtual screening approach toward the discovery of histone deacetylase inhibitors: identification of promising zinc-chelating groups.
    Park H; Kim S; Kim YE; Lim SJ
    ChemMedChem; 2010 Apr; 5(4):591-7. PubMed ID: 20157916
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Comparative molecular dynamics simulations of histone deacetylase-like protein: binding modes and free energy analysis to hydroxamic acid inhibitors.
    Yan C; Xiu Z; Li X; Li S; Hao C; Teng H
    Proteins; 2008 Oct; 73(1):134-49. PubMed ID: 18398905
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Real-time monitoring of conformational transitions of single-molecule histone deacetylase 8 with nanocircuits.
    You S; Froberg J; Yu J; Haldar M; Sedigh A; Mallik S; Srivastava DK; Choi Y
    Chem Commun (Camb); 2017 Mar; 53(23):3307-3310. PubMed ID: 28261707
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A miniaturized readout strategy for endogenous histone deacetylase activity.
    Jost JO; Hanswillemenke A; Schwarzer D
    Mol Biosyst; 2015 Jul; 11(7):1820-3. PubMed ID: 26009008
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design and synthesis of non-hydroxamate histone deacetylase inhibitors: identification of a selective histone acetylating agent.
    Suzuki T; Matsuura A; Kouketsu A; Hisakawa S; Nakagawa H; Miyata N
    Bioorg Med Chem; 2005 Jul; 13(13):4332-42. PubMed ID: 15927839
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors.
    De Vreese R; D'hooghe M
    Eur J Med Chem; 2017 Jul; 135():174-195. PubMed ID: 28453994
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structure-activity relationships of hydroxamate-based histone deacetylase-8 inhibitors: reality behind anticancer drug discovery.
    Amin SA; Adhikari N; Jha T
    Future Med Chem; 2017 Dec; 9(18):2211-2237. PubMed ID: 29182018
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Tescalcin is a potential target of class I histone deacetylase inhibitors in neurons.
    Takamatsu G; Katagiri C; Tomoyuki T; Shimizu-Okabe C; Nakamura W; Nakamura-Higa M; Hayakawa T; Wakabayashi S; Kondo T; Takayama C; Matsushita M
    Biochem Biophys Res Commun; 2017 Jan; 482(4):1327-1333. PubMed ID: 27939885
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.