BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 25915621)

  • 1. The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
    Talapatra SK; Harker B; Welburn JP
    Elife; 2015 Apr; 4():. PubMed ID: 25915621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation.
    McHugh T; Zou J; Volkov VA; Bertin A; Talapatra SK; Rappsilber J; Dogterom M; Welburn JPI
    J Cell Sci; 2019 Jan; 132(4):. PubMed ID: 30578316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly.
    Ems-McClung SC; Hertzer KM; Zhang X; Miller MW; Walczak CE
    Mol Biol Cell; 2007 Jan; 18(1):282-94. PubMed ID: 17093055
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aurora B inhibits MCAK activity through a phosphoconformational switch that reduces microtubule association.
    Ems-McClung SC; Hainline SG; Devare J; Zong H; Cai S; Carnes SK; Shaw SL; Walczak CE
    Curr Biol; 2013 Dec; 23(24):2491-9. PubMed ID: 24291095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.
    Friel CT; Howard J
    EMBO J; 2011 Aug; 30(19):3928-39. PubMed ID: 21873978
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK.
    Hertzer KM; Ems-McClung SC; Kline-Smith SL; Lipkin TG; Gilbert SP; Walczak CE
    Mol Biol Cell; 2006 Feb; 17(2):700-10. PubMed ID: 16291860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insight into the molecular mechanism of the multitasking kinesin-8 motor.
    Peters C; Brejc K; Belmont L; Bodey AJ; Lee Y; Yu M; Guo J; Sakowicz R; Hartman J; Moores CA
    EMBO J; 2010 Oct; 29(20):3437-47. PubMed ID: 20818331
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition.
    Patel JT; Belsham HR; Rathbone AJ; Wickstead B; Gell C; Friel CT
    Open Biol; 2016 Oct; 6(10):. PubMed ID: 27733589
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microtubule minus-end stability is dictated by the tubulin off-rate.
    Strothman C; Farmer V; Arpağ G; Rodgers N; Podolski M; Norris S; Ohi R; Zanic M
    J Cell Biol; 2019 Sep; 218(9):2841-2853. PubMed ID: 31420452
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization.
    Burns KM; Wagenbach M; Wordeman L; Schriemer DC
    Structure; 2014 Aug; 22(8):1173-1183. PubMed ID: 25066134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends.
    Helenius J; Brouhard G; Kalaidzidis Y; Diez S; Howard J
    Nature; 2006 May; 441(7089):115-9. PubMed ID: 16672973
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C-terminus of mitotic centromere-associated kinesin (MCAK) inhibits its lattice-stimulated ATPase activity.
    Moore A; Wordeman L
    Biochem J; 2004 Oct; 383(Pt 2):227-35. PubMed ID: 15250824
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
    Vinogradova MV; Malanina GG; Reddy VS; Reddy AS; Fletterick RJ
    J Struct Biol; 2008 Jul; 163(1):76-83. PubMed ID: 18513992
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
    Bodrug T; Wilson-Kubalek EM; Nithianantham S; Thompson AF; Alfieri A; Gaska I; Major J; Debs G; Inagaki S; Gutierrez P; Gheber L; McKenney RJ; Sindelar CV; Milligan R; Stumpff J; Rosenfeld SS; Forth ST; Al-Bassam J
    Elife; 2020 Jan; 9():. PubMed ID: 31958056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends.
    Hunter AW; Caplow M; Coy DL; Hancock WO; Diez S; Wordeman L; Howard J
    Mol Cell; 2003 Feb; 11(2):445-57. PubMed ID: 12620232
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
    Peña A; Sweeney A; Cook AD; Locke J; Topf M; Moores CA
    Structure; 2020 Apr; 28(4):450-457.e5. PubMed ID: 32084356
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.
    Wang W; Shen T; Guerois R; Zhang F; Kuerban H; Lv Y; Gigant B; Knossow M; Wang C
    J Biol Chem; 2015 Jul; 290(30):18721-31. PubMed ID: 26055718
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modeling processive motion of kinesin-13 MCAK and kinesin-14 Cik1-Kar3 molecular motors.
    Xie P
    Protein Sci; 2021 Oct; 30(10):2092-2105. PubMed ID: 34382258
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity.
    Lan W; Zhang X; Kline-Smith SL; Rosasco SE; Barrett-Wilt GA; Shabanowitz J; Hunt DF; Walczak CE; Stukenberg PT
    Curr Biol; 2004 Feb; 14(4):273-86. PubMed ID: 14972678
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of the kinesin-13 neck in microtubule depolymerization.
    Moores CA; Cooper J; Wagenbach M; Ovechkina Y; Wordeman L; Milligan RA
    Cell Cycle; 2006 Aug; 5(16):1812-5. PubMed ID: 16929184
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.