BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 25916846)

  • 1. Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex.
    Kim SA; Chatterjee N; Jennings MJ; Bartholomew B; Tan S
    Nucleic Acids Res; 2015 May; 43(10):4868-80. PubMed ID: 25916846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
    Kim SA; Zhu J; Yennawar N; Eek P; Tan S
    Mol Cell; 2020 Jun; 78(5):903-914.e4. PubMed ID: 32396821
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation.
    Pilotto S; Speranzini V; Tortorici M; Durand D; Fish A; Valente S; Forneris F; Mai A; Sixma TK; Vachette P; Mattevi A
    Proc Natl Acad Sci U S A; 2015 Mar; 112(9):2752-7. PubMed ID: 25730864
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase.
    Yang M; Gocke CB; Luo X; Borek D; Tomchick DR; Machius M; Otwinowski Z; Yu H
    Mol Cell; 2006 Aug; 23(3):377-87. PubMed ID: 16885027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST.
    Hwang S; Schmitt AA; Luteran AE; Toone EJ; McCafferty DG
    Biochemistry; 2011 Feb; 50(4):546-57. PubMed ID: 21142040
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemically Sumoylated Histone H4 Stimulates Intranucleosomal Demethylation by the LSD1-CoREST Complex.
    Dhall A; Weller CE; Chu A; Shelton PMM; Chatterjee C
    ACS Chem Biol; 2017 Sep; 12(9):2275-2280. PubMed ID: 28832116
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring the Active Center of the LSD1/CoREST Complex by Molecular Dynamics Simulation Utilizing Its Co-crystallized Co-factor Tetrahydrofolate as a Probe.
    Zalloum WA; Zalloum HM
    J Chem Inf Model; 2017 Dec; 57(12):3022-3031. PubMed ID: 29161028
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex.
    Song Y; Dagil L; Fairall L; Robertson N; Wu M; Ragan TJ; Savva CG; Saleh A; Morone N; Kunze MBA; Jamieson AG; Cole PA; Hansen DF; Schwabe JWR
    Cell Rep; 2020 Feb; 30(8):2699-2711.e8. PubMed ID: 32101746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation.
    Dhall A; Shelton PMM; Delachat AM; Leonen CJA; Fierz B; Chatterjee C
    Biochemistry; 2020 Jul; 59(27):2479-2483. PubMed ID: 32567837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LSD1/CoREST is an allosteric nanoscale clamp regulated by H3-histone-tail molecular recognition.
    Baron R; Vellore NA
    Proc Natl Acad Sci U S A; 2012 Jul; 109(31):12509-14. PubMed ID: 22802671
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation.
    Lee MG; Wynder C; Cooch N; Shiekhattar R
    Nature; 2005 Sep; 437(7057):432-5. PubMed ID: 16079794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate.
    Luka Z; Pakhomova S; Loukachevitch LV; Calcutt MW; Newcomer ME; Wagner C
    Protein Sci; 2014 Jul; 23(7):993-8. PubMed ID: 24715612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development.
    Lopez CI; Saud KE; Aguilar R; Berndt FA; Cánovas J; Montecino M; Kukuljan M
    Dev Neurobiol; 2016 Dec; 76(12):1360-1373. PubMed ID: 27112428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of LSD1 histone demethylase activity by its associated factors.
    Shi YJ; Matson C; Lan F; Iwase S; Baba T; Shi Y
    Mol Cell; 2005 Sep; 19(6):857-64. PubMed ID: 16140033
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.
    Lu Y; Wajapeyee N; Turker MS; Glazer PM
    Cell Rep; 2014 Jul; 8(2):501-13. PubMed ID: 25043185
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PIASγ controls stability and facilitates SUMO-2 conjugation to CoREST family of transcriptional co-repressors.
    Sáez JE; Arredondo C; Rivera C; Andrés ME
    Biochem J; 2018 Apr; 475(8):1441-1454. PubMed ID: 29555846
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
    Amano Y; Kikuchi M; Sato S; Yokoyama S; Umehara T; Umezawa N; Higuchi T
    Bioorg Med Chem; 2017 May; 25(9):2617-2624. PubMed ID: 28336409
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer.
    Tan AHY; Tu W; McCuaig R; Hardy K; Donovan T; Tsimbalyuk S; Forwood JK; Rao S
    Front Immunol; 2019; 10():1351. PubMed ID: 31249575
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular mimicry and ligand recognition in binding and catalysis by the histone demethylase LSD1-CoREST complex.
    Baron R; Binda C; Tortorici M; McCammon JA; Mattevi A
    Structure; 2011 Feb; 19(2):212-20. PubMed ID: 21300290
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.
    Foster CT; Dovey OM; Lezina L; Luo JL; Gant TW; Barlev N; Bradley A; Cowley SM
    Mol Cell Biol; 2010 Oct; 30(20):4851-63. PubMed ID: 20713442
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.