429 related articles for article (PubMed ID: 25918388)
1. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X; Maretzky T; Weskamp G; Monette S; Qing X; Issuree PD; Crawford HC; McIlwain DR; Mak TW; Salmon JE; Blobel CP
Proc Natl Acad Sci U S A; 2015 May; 112(19):6080-5. PubMed ID: 25918388
[TBL] [Abstract][Full Text] [Related]
2. iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Maretzky T; McIlwain DR; Issuree PD; Li X; Malapeira J; Amin S; Lang PA; Mak TW; Blobel CP
Proc Natl Acad Sci U S A; 2013 Jul; 110(28):11433-8. PubMed ID: 23801765
[TBL] [Abstract][Full Text] [Related]
3. ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Weskamp G; Tüshaus J; Li D; Feederle R; Maretzky T; Swendemann S; Falck-Pedersen E; McIlwain DR; Mak TW; Salmon JE; Lichtenthaler SF; Blobel CP
J Biol Chem; 2020 Mar; 295(13):4350-4358. PubMed ID: 32060096
[TBL] [Abstract][Full Text] [Related]
4. Identification of Molecular Determinants in iRhoms1 and 2 That Contribute to the Substrate Selectivity of Stimulated ADAM17.
Zhao Y; Dávila EM; Li X; Tang B; Rabinowitsch AI; Perez-Aguilar JM; Blobel CP
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361585
[TBL] [Abstract][Full Text] [Related]
5. The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.
Urriola-Muñoz P; Li X; Maretzky T; McIlwain DR; Mak TW; Reyes JG; Blobel CP; Moreno RD
J Cell Physiol; 2018 Mar; 233(3):2247-2256. PubMed ID: 28703301
[TBL] [Abstract][Full Text] [Related]
6. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
[TBL] [Abstract][Full Text] [Related]
7. Role of iRhoms 1 and 2 in Endochondral Ossification.
Fang R; Haxaire C; Otero M; Lessard S; Weskamp G; McIlwain DR; Mak TW; Lichtenthaler SF; Blobel CP
Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33227998
[TBL] [Abstract][Full Text] [Related]
8. Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Chalaris A; Adam N; Sina C; Rosenstiel P; Lehmann-Koch J; Schirmacher P; Hartmann D; Cichy J; Gavrilova O; Schreiber S; Jostock T; Matthews V; Häsler R; Becker C; Neurath MF; Reiss K; Saftig P; Scheller J; Rose-John S
J Exp Med; 2010 Aug; 207(8):1617-24. PubMed ID: 20603312
[TBL] [Abstract][Full Text] [Related]
9. Novel functions of inactive rhomboid proteins in immunity and disease.
Geesala R; Issuree PD; Maretzky T
J Leukoc Biol; 2019 Oct; 106(4):823-835. PubMed ID: 31369701
[TBL] [Abstract][Full Text] [Related]
10. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Li X; Maretzky T; Perez-Aguilar JM; Monette S; Weskamp G; Le Gall S; Beutler B; Weinstein H; Blobel CP
J Cell Sci; 2017 Mar; 130(5):868-878. PubMed ID: 28104813
[TBL] [Abstract][Full Text] [Related]
11. iRhom2: An Emerging Adaptor Regulating Immunity and Disease.
Al-Salihi MA; Lang PA
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32911849
[TBL] [Abstract][Full Text] [Related]
12. Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
Christova Y; Adrain C; Bambrough P; Ibrahim A; Freeman M
EMBO Rep; 2013 Oct; 14(10):884-90. PubMed ID: 23969955
[TBL] [Abstract][Full Text] [Related]
13. HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells.
Uttarwar L; Peng F; Wu D; Kumar S; Gao B; Ingram AJ; Krepinsky JC
Am J Physiol Renal Physiol; 2011 Apr; 300(4):F921-31. PubMed ID: 21289053
[TBL] [Abstract][Full Text] [Related]
14. Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.
Shimoda M; Horiuchi K; Sasaki A; Tsukamoto T; Okabayashi K; Hasegawa H; Kitagawa Y; Okada Y
EBioMedicine; 2016 Mar; 5():114-24. PubMed ID: 27077118
[TBL] [Abstract][Full Text] [Related]
15. Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
Schwarz J; Broder C; Helmstetter A; Schmidt S; Yan I; Müller M; Schmidt-Arras D; Becker-Pauly C; Koch-Nolte F; Mittrücker HW; Rabe B; Rose-John S; Chalaris A
Biochim Biophys Acta; 2013 Dec; 1833(12):3355-3367. PubMed ID: 24135057
[TBL] [Abstract][Full Text] [Related]
16. A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17.
Maretzky T; Zhou W; Huang XY; Blobel CP
Oncogene; 2011 Feb; 30(5):611-8. PubMed ID: 20871631
[TBL] [Abstract][Full Text] [Related]
17. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
Maney SK; McIlwain DR; Polz R; Pandyra AA; Sundaram B; Wolff D; Ohishi K; Maretzky T; Brooke MA; Evers A; Vasudevan AA; Aghaeepour N; Scheller J; Münk C; Häussinger D; Mak TW; Nolan GP; Kelsell DP; Blobel CP; Lang KS; Lang PA
Sci Signal; 2015 Nov; 8(401):ra109. PubMed ID: 26535007
[TBL] [Abstract][Full Text] [Related]
18. Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
Lora J; Weskamp G; Li TM; Maretzky T; Shola DTN; Monette S; Lichtenthaler SF; Lu TT; Yang C; Blobel CP
J Biol Chem; 2021; 296():100733. PubMed ID: 33957124
[TBL] [Abstract][Full Text] [Related]
19. Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17.
Sahin U; Blobel CP
FEBS Lett; 2007 Jan; 581(1):41-4. PubMed ID: 17169360
[TBL] [Abstract][Full Text] [Related]
20. Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.
Berasain C; Nicou A; Garcia-Irigoyen O; Latasa MU; Urtasun R; Elizalde M; Salis F; Perugorría MJ; Prieto J; Recio JA; Corrales FJ; Avila MA
Dig Dis; 2012; 30(5):524-31. PubMed ID: 23108309
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]