These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

428 related articles for article (PubMed ID: 25918388)

  • 1. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
    Li X; Maretzky T; Weskamp G; Monette S; Qing X; Issuree PD; Crawford HC; McIlwain DR; Mak TW; Salmon JE; Blobel CP
    Proc Natl Acad Sci U S A; 2015 May; 112(19):6080-5. PubMed ID: 25918388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
    Maretzky T; McIlwain DR; Issuree PD; Li X; Malapeira J; Amin S; Lang PA; Mak TW; Blobel CP
    Proc Natl Acad Sci U S A; 2013 Jul; 110(28):11433-8. PubMed ID: 23801765
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
    Weskamp G; Tüshaus J; Li D; Feederle R; Maretzky T; Swendemann S; Falck-Pedersen E; McIlwain DR; Mak TW; Salmon JE; Lichtenthaler SF; Blobel CP
    J Biol Chem; 2020 Mar; 295(13):4350-4358. PubMed ID: 32060096
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Molecular Determinants in iRhoms1 and 2 That Contribute to the Substrate Selectivity of Stimulated ADAM17.
    Zhao Y; Dávila EM; Li X; Tang B; Rabinowitsch AI; Perez-Aguilar JM; Blobel CP
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.
    Urriola-Muñoz P; Li X; Maretzky T; McIlwain DR; Mak TW; Reyes JG; Blobel CP; Moreno RD
    J Cell Physiol; 2018 Mar; 233(3):2247-2256. PubMed ID: 28703301
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
    Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
    FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of iRhoms 1 and 2 in Endochondral Ossification.
    Fang R; Haxaire C; Otero M; Lessard S; Weskamp G; McIlwain DR; Mak TW; Lichtenthaler SF; Blobel CP
    Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33227998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of iRhom2 in Olfaction: Implications for Odorant Receptor Regulation and Activity-Dependent Adaptation.
    Azzopardi SA; Lu HY; Monette S; Rabinowitsch AI; Salmon JE; Matsunami H; Blobel CP
    Int J Mol Sci; 2024 May; 25(11):. PubMed ID: 38892263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
    Chalaris A; Adam N; Sina C; Rosenstiel P; Lehmann-Koch J; Schirmacher P; Hartmann D; Cichy J; Gavrilova O; Schreiber S; Jostock T; Matthews V; Häsler R; Becker C; Neurath MF; Reiss K; Saftig P; Scheller J; Rose-John S
    J Exp Med; 2010 Aug; 207(8):1617-24. PubMed ID: 20603312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel functions of inactive rhomboid proteins in immunity and disease.
    Geesala R; Issuree PD; Maretzky T
    J Leukoc Biol; 2019 Oct; 106(4):823-835. PubMed ID: 31369701
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
    Li X; Maretzky T; Perez-Aguilar JM; Monette S; Weskamp G; Le Gall S; Beutler B; Weinstein H; Blobel CP
    J Cell Sci; 2017 Mar; 130(5):868-878. PubMed ID: 28104813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. iRhom2: An Emerging Adaptor Regulating Immunity and Disease.
    Al-Salihi MA; Lang PA
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32911849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
    Christova Y; Adrain C; Bambrough P; Ibrahim A; Freeman M
    EMBO Rep; 2013 Oct; 14(10):884-90. PubMed ID: 23969955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells.
    Uttarwar L; Peng F; Wu D; Kumar S; Gao B; Ingram AJ; Krepinsky JC
    Am J Physiol Renal Physiol; 2011 Apr; 300(4):F921-31. PubMed ID: 21289053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.
    Shimoda M; Horiuchi K; Sasaki A; Tsukamoto T; Okabayashi K; Hasegawa H; Kitagawa Y; Okada Y
    EBioMedicine; 2016 Mar; 5():114-24. PubMed ID: 27077118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
    Schwarz J; Broder C; Helmstetter A; Schmidt S; Yan I; Müller M; Schmidt-Arras D; Becker-Pauly C; Koch-Nolte F; Mittrücker HW; Rabe B; Rose-John S; Chalaris A
    Biochim Biophys Acta; 2013 Dec; 1833(12):3355-3367. PubMed ID: 24135057
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17.
    Maretzky T; Zhou W; Huang XY; Blobel CP
    Oncogene; 2011 Feb; 30(5):611-8. PubMed ID: 20871631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
    Maney SK; McIlwain DR; Polz R; Pandyra AA; Sundaram B; Wolff D; Ohishi K; Maretzky T; Brooke MA; Evers A; Vasudevan AA; Aghaeepour N; Scheller J; Münk C; Häussinger D; Mak TW; Nolan GP; Kelsell DP; Blobel CP; Lang KS; Lang PA
    Sci Signal; 2015 Nov; 8(401):ra109. PubMed ID: 26535007
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
    Lora J; Weskamp G; Li TM; Maretzky T; Shola DTN; Monette S; Lichtenthaler SF; Lu TT; Yang C; Blobel CP
    J Biol Chem; 2021; 296():100733. PubMed ID: 33957124
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17.
    Sahin U; Blobel CP
    FEBS Lett; 2007 Jan; 581(1):41-4. PubMed ID: 17169360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.