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6. Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans. Gaston-Massuet C; Andoniadou CL; Signore M; Jayakody SA; Charolidi N; Kyeyune R; Vernay B; Jacques TS; Taketo MM; Le Tissier P; Dattani MT; Martinez-Barbera JP Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11482-7. PubMed ID: 21636786 [TBL] [Abstract][Full Text] [Related]
7. Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Gonzalez-Meljem JM; Haston S; Carreno G; Apps JR; Pozzi S; Stache C; Kaushal G; Virasami A; Panousopoulos L; Mousavy-Gharavy SN; Guerrero A; Rashid M; Jani N; Goding CR; Jacques TS; Adams DJ; Gil J; Andoniadou CL; Martinez-Barbera JP Nat Commun; 2017 Nov; 8(1):1819. PubMed ID: 29180744 [TBL] [Abstract][Full Text] [Related]
8. Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target. Apps JR; Carreno G; Gonzalez-Meljem JM; Haston S; Guiho R; Cooper JE; Manshaei S; Jani N; Hölsken A; Pettorini B; Beynon RJ; Simpson DM; Fraser HC; Hong Y; Hallang S; Stone TJ; Virasami A; Donson AM; Jones D; Aquilina K; Spoudeas H; Joshi AR; Grundy R; Storer LCD; Korbonits M; Hilton DA; Tossell K; Thavaraj S; Ungless MA; Gil J; Buslei R; Hankinson T; Hargrave D; Goding C; Andoniadou CL; Brogan P; Jacques TS; Williams HJ; Martinez-Barbera JP Acta Neuropathol; 2018 May; 135(5):757-777. PubMed ID: 29541918 [TBL] [Abstract][Full Text] [Related]
9. Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression. Apps JR; Gonzalez-Meljem JM; Guiho R; Pickles JC; Prince E; Schwalbe E; Joshi N; Stone TJ; Ogunbiyi O; Chalker J; Bassey A; Otto G; Davies R; Hughes D; Brandner S; Tan E; Lee V; Hayhurst C; Kline C; Castellano S; Hankinson T; Deutschbein T; Jacques TS; Martinez-Barbera JP Acta Neuropathol Commun; 2024 Aug; 12(1):127. PubMed ID: 39127699 [TBL] [Abstract][Full Text] [Related]
10. The Wnt signalling cascade and the adherens junction complex in craniopharyngioma tumorigenesis. Preda V; Larkin SJ; Karavitaki N; Ansorge O; Grossman AB Endocr Pathol; 2015 Mar; 26(1):1-8. PubMed ID: 25355426 [TBL] [Abstract][Full Text] [Related]
11. Pathology and pathogenesis of craniopharyngiomas. Larkin SJ; Ansorge O Pituitary; 2013 Mar; 16(1):9-17. PubMed ID: 22886701 [TBL] [Abstract][Full Text] [Related]
12. Study of β-catenin and BRAF alterations in adamantinomatous and papillary craniopharyngiomas: mutation analysis with immunohistochemical correlation in 54 cases. Malgulwar PB; Nambirajan A; Pathak P; Faruq M; Suri V; Sarkar C; Jagdevan A; Sharma BS; Sharma MC J Neurooncol; 2017 Jul; 133(3):487-495. PubMed ID: 28500561 [TBL] [Abstract][Full Text] [Related]
13. Beta-catenin stimulates pituitary stem cells to form aggressive tumors. Camper SA Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11303-4. PubMed ID: 21719710 [No Abstract] [Full Text] [Related]
15. BRAF V600E mutations are characteristic for papillary craniopharyngioma and may coexist with CTNNB1-mutated adamantinomatous craniopharyngioma. Larkin SJ; Preda V; Karavitaki N; Grossman A; Ansorge O Acta Neuropathol; 2014; 127(6):927-9. PubMed ID: 24715106 [No Abstract] [Full Text] [Related]
16. Tumour cell migration in adamantinomatous craniopharyngiomas is promoted by activated Wnt-signalling. Hölsken A; Buchfelder M; Fahlbusch R; Blümcke I; Buslei R Acta Neuropathol; 2010 May; 119(5):631-9. PubMed ID: 20131060 [TBL] [Abstract][Full Text] [Related]
17. Possible linkage between specific histological structures and aberrant reactivation of the Wnt pathway in adamantinomatous craniopharyngioma. Kato K; Nakatani Y; Kanno H; Inayama Y; Ijiri R; Nagahara N; Miyake T; Tanaka M; Ito Y; Aida N; Tachibana K; Sekido K; Tanaka Y J Pathol; 2004 Jul; 203(3):814-21. PubMed ID: 15221941 [TBL] [Abstract][Full Text] [Related]
18. Impact of the Canonical Wnt Pathway Activation on the Pathogenesis and Prognosis of Adamantinomatous Craniopharyngiomas. Jucá CEB; Colli LM; Martins CS; Campanini ML; Paixão B; Jucá RV; Saggioro FP; de Oliveira RS; Moreira AC; Machado HR; Neder L; Antonini SR; de Castro M Horm Metab Res; 2018 Jul; 50(7):575-581. PubMed ID: 29625497 [No Abstract] [Full Text] [Related]
19. Sonic Hedgehog pathway is upregulated in adamantinomatous craniopharyngiomas. Gomes DC; Jamra SA; Leal LF; Colli LM; Campanini ML; Oliveira RS; Martinelli CE; Elias PC; Moreira AC; Machado HR; Saggioro F; Neder L; Castro M; Antonini SR Eur J Endocrinol; 2015 May; 172(5):603-8. PubMed ID: 25693592 [TBL] [Abstract][Full Text] [Related]
20. Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region. Buslei R; Nolde M; Hofmann B; Meissner S; Eyupoglu IY; Siebzehnrübl F; Hahnen E; Kreutzer J; Fahlbusch R Acta Neuropathol; 2005 Jun; 109(6):589-97. PubMed ID: 15891929 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]