These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 25929584)

  • 21. Specific inhibitions of annonaceous acetogenins on class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae.
    Feng L; Zhou L; Sun Y; Gui J; Wang X; Wu P; Wan J; Ren Y; Qiu S; Wei X; Li J
    Bioorg Med Chem; 2011 Jun; 19(11):3512-9. PubMed ID: 21550257
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structure-based rational quest for potential novel inhibitors of human HMG-CoA reductase by combining CoMFA 3D QSAR modeling and virtual screening.
    Zhang QY; Wan J; Xu X; Yang GF; Ren YL; Liu JJ; Wang H; Guo Y
    J Comb Chem; 2007; 9(1):131-8. PubMed ID: 17206841
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Exploring Leishmania donovani 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) as a potential drug target by biochemical, biophysical and inhibition studies.
    Dinesh N; Pallerla DS; Kaur PK; Kishore Babu N; Singh S
    Microb Pathog; 2014 Jan; 66():14-23. PubMed ID: 24239940
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase lower fecundity in the German cockroach: correlation between the effects on fecundity in vivo with the inhibition of enzymatic activity in embryo cells.
    Zapata R; Piulachs MD; Bellés X
    Pest Manag Sci; 2003 Oct; 59(10):1111-7. PubMed ID: 14561068
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.
    Lingham RB; Silverman KC; Jayasuriya H; Kim BM; Amo SE; Wilson FR; Rew DJ; Schaber MD; Bergstrom JD; Koblan KS; Graham SL; Kohl NE; Gibbs JB; Singh SB
    J Med Chem; 1998 Nov; 41(23):4492-501. PubMed ID: 9804689
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity.
    Theivagt AE; Amanti EN; Beresford NJ; Tabernero L; Friesen JA
    Biochemistry; 2006 Dec; 45(48):14397-406. PubMed ID: 17128979
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structural mechanism for statin inhibition of HMG-CoA reductase.
    Istvan ES; Deisenhofer J
    Science; 2001 May; 292(5519):1160-4. PubMed ID: 11349148
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Discriminating of HMG-CoA reductase inhibitors and decoys using self-organizing maps.
    Wang Z; Yan A
    Mol Divers; 2011 Aug; 15(3):655-63. PubMed ID: 21072588
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors.
    Hosoda S; Matsuda D; Tomoda H; Hashimoto M; Aoyama H; Hashimoto Y
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4228-31. PubMed ID: 19502059
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent.
    Sashidhara KV; Singh SP; Srivastava A; Puri A; Chhonker YS; Bhatta RS; Shah P; Siddiqi MI
    Eur J Med Chem; 2011 Oct; 46(10):5206-11. PubMed ID: 21872367
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design and synthesis of dual-action inhibitors targeting histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme A reductase for cancer treatment.
    Chen JB; Chern TR; Wei TT; Chen CC; Lin JH; Fang JM
    J Med Chem; 2013 May; 56(9):3645-55. PubMed ID: 23570542
    [TBL] [Abstract][Full Text] [Related]  

  • 32. HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins.
    Dansette PM; Jaoen M; Pons C
    Exp Toxicol Pathol; 2000 May; 52(2):145-8. PubMed ID: 10965989
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii.
    Hedl M; Rodwell VW
    Protein Sci; 2004 Jun; 13(6):1693-7. PubMed ID: 15152097
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
    Pfefferkorn JA; Choi C; Song Y; Trivedi BK; Larsen SD; Askew V; Dillon L; Hanselman JC; Lin Z; Lu G; Robertson A; Sekerke C; Auerbach B; Pavlovsky A; Harris MS; Bainbridge G; Caspers N
    Bioorg Med Chem Lett; 2007 Aug; 17(16):4531-7. PubMed ID: 17574411
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Recombinant Schistosoma mansoni 3-hydroxymethylglutaryl-coenzyme-A reductase has different inhibitor kinetics compared to the mammalian host enzyme.
    El-Meanawy A; Hammd H; Chen GZ; Rottman F; Bennett JL
    Trop Gastroenterol; 2005; 26(3):132-5. PubMed ID: 16512462
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Asymmetric synthesis of the HMG-CoA reductase inhibitor atorvastatin calcium: an organocatalytic anhydride desymmetrization and cyanide-free side chain elongation approach.
    Chen X; Xiong F; Chen W; He Q; Chen F
    J Org Chem; 2014 Mar; 79(6):2723-8. PubMed ID: 24575888
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Morelloflavone from Garcinia dulcis as a novel biflavonoid inhibitor of HMG-CoA reductase.
    Tuansulong KA; Hutadilok-Towatana N; Mahabusarakam W; Pinkaew D; Fujise K
    Phytother Res; 2011 Mar; 25(3):424-8. PubMed ID: 20734327
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.
    Park WK; Kennedy RM; Larsen SD; Miller S; Roth BD; Song Y; Steinbaugh BA; Sun K; Tait BD; Kowala MC; Trivedi BK; Auerbach B; Askew V; Dillon L; Hanselman JC; Lin Z; Lu GH; Robertson A; Sekerke C
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1151-6. PubMed ID: 18155906
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Pyrazole inhibitors of HMG-CoA reductase: an attempt to dramatically reduce synthetic complexity through minimal analog re-design.
    Larsen SD; Poel TJ; Filipski KJ; Kohrt JT; Pfefferkorn JA; Sorenson RJ; Tait BD; Askew V; Dillon L; Hanselman JC; Lu GH; Robertson A; Sekerke C; Kowala MC; Auerbach BJ
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5567-72. PubMed ID: 17764936
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural mechanism for statin inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
    Istvan ES
    Am Heart J; 2002 Dec; 144(6 Suppl):S27-32. PubMed ID: 12486413
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 4.