BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 25935648)

  • 1. Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants.
    Al-Horani RA; Gailani D; Desai UR
    Thromb Res; 2015 Aug; 136(2):379-87. PubMed ID: 25935648
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides.
    Al-Horani RA; Desai UR
    J Med Chem; 2014 Jun; 57(11):4805-18. PubMed ID: 24844380
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa.
    Al-Horani RA; Ponnusamy P; Mehta AY; Gailani D; Desai UR
    J Med Chem; 2013 Feb; 56(3):867-78. PubMed ID: 23316863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Medically-induced hemophilia C to treat thrombosis.
    Schmaier AH
    Thromb Res; 2015 Aug; 136(2):185-6. PubMed ID: 26024825
    [No Abstract]   [Full Text] [Related]  

  • 5. Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors.
    Argade MD; Mehta AY; Sarkar A; Desai UR
    J Med Chem; 2014 Apr; 57(8):3559-69. PubMed ID: 24666186
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia.
    Kar S; Mottamal M; Al-Horani RA
    ChemistryOpen; 2020 Nov; 9(11):1161-1172. PubMed ID: 33204588
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies.
    Al-Horani RA; Parsaeian E; Mohammad M; Mottamal M
    Chem Biol Drug Des; 2022 Jul; 100(1):64-79. PubMed ID: 35377529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
    Al-Horani RA; Abdelfadiel EI; Afosah DK; Morla S; Sistla JC; Mohammed B; Martin EJ; Sakagami M; Brophy DF; Desai UR
    J Thromb Haemost; 2019 Dec; 17(12):2110-2122. PubMed ID: 31397071
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Factor XIa inhibitors: A review of the patent literature.
    Al-Horani RA; Desai UR
    Expert Opin Ther Pat; 2016; 26(3):323-45. PubMed ID: 26881476
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Investigation of the anticoagulant activity of cyclic sulfated glycosaminoglycan mimetics.
    Chiles R; Afosah DK; Al-Horani RA
    Carbohydr Res; 2023 Jul; 529():108831. PubMed ID: 37209666
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a heparin binding site on the heavy chain of factor XI.
    Zhao M; Abdel-Razek T; Sun MF; Gailani D
    J Biol Chem; 1998 Nov; 273(47):31153-9. PubMed ID: 9813019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lignosulfonic Acid Sodium Is a Noncompetitive Inhibitor of Human Factor XIa.
    Kar S; Bankston P; Afosah DK; Al-Horani RA
    Pharmaceuticals (Basel); 2021 Aug; 14(9):. PubMed ID: 34577586
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants.
    Lin J; Deng H; Jin L; Pandey P; Quinn J; Cantin S; Rynkiewicz MJ; Gorga JC; Bibbins F; Celatka CA; Nagafuji P; Bannister TD; Meyers HV; Babine RE; Hayward NJ; Weaver D; Benjamin H; Stassen F; Abdel-Meguid SS; Strickler JE
    J Med Chem; 2006 Dec; 49(26):7781-91. PubMed ID: 17181160
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of low molecular weight heparin and low molecular weight dextran sulfate on the inhibition of coagulation factor XIa by serpins.
    Mauron T; Lämmle B; Wuillemin WA
    Thromb Haemost; 1998 Jul; 80(1):82-6. PubMed ID: 9684790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fragment-Based Lead Generation of 5-Phenyl-1
    Wei Q; Zheng Z; Zhang S; Zheng X; Meng F; Yuan J; Xu Y; Huang C
    Molecules; 2018 Aug; 23(8):. PubMed ID: 30103465
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of contact system proteases by glycosaminoglycans. Selective enhancement of the inhibition of factor XIa.
    Wuillemin WA; Eldering E; Citarella F; de Ruig CP; ten Cate H; Hack CE
    J Biol Chem; 1996 May; 271(22):12913-8. PubMed ID: 8662679
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.
    Karuturi R; Al-Horani RA; Mehta SC; Gailani D; Desai UR
    J Med Chem; 2013 Mar; 56(6):2415-28. PubMed ID: 23451707
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of Chromen-7-yl Furan-2-Carboxylate as a Potent and Selective Factor XIa Inhibitor.
    Obaidullah AJ; Al-Horani RA
    Cardiovasc Hematol Agents Med Chem; 2017 Nov; 15(1):40-48. PubMed ID: 28552062
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studies on fragment-based design of allosteric inhibitors of human factor XIa.
    Boothello RS; Sankaranarayanan NV; Afosah DK; Karuturi R; Al-Horani RA; Desai UR
    Bioorg Med Chem; 2020 Dec; 28(23):115762. PubMed ID: 32992249
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor.
    Yang L; Sun MF; Gailani D; Rezaie AR
    Biochemistry; 2009 Feb; 48(7):1517-24. PubMed ID: 19178150
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.