148 related articles for article (PubMed ID: 25937300)
1. Nelfinavir, an HIV protease inhibitor, induces apoptosis and cell cycle arrest in human cervical cancer cells via the ROS-dependent mitochondrial pathway.
Xiang T; Du L; Pham P; Zhu B; Jiang S
Cancer Lett; 2015 Aug; 364(1):79-88. PubMed ID: 25937300
[TBL] [Abstract][Full Text] [Related]
2. Bortezomib targets the caspase-like proteasome activity in cervical cancer cells, triggering apoptosis that can be enhanced by nelfinavir.
Bruning A; Vogel M; Mylonas I; Friese K; Burges A
Curr Cancer Drug Targets; 2011 Sep; 11(7):799-809. PubMed ID: 21762082
[TBL] [Abstract][Full Text] [Related]
3. HIV protease inhibitor nelfinavir inhibits growth of human melanoma cells by induction of cell cycle arrest.
Jiang W; Mikochik PJ; Ra JH; Lei H; Flaherty KT; Winkler JD; Spitz FR
Cancer Res; 2007 Feb; 67(3):1221-7. PubMed ID: 17283158
[TBL] [Abstract][Full Text] [Related]
4. Antitumour effects of a protease inhibitor, nelfinavir, in hepatocellular carcinoma cancer cells.
Sun L; Niu L; Zhu X; Hao J; Wang P; Wang H
J Chemother; 2012 Jun; 24(3):161-6. PubMed ID: 22759761
[TBL] [Abstract][Full Text] [Related]
5. Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.
Gills JJ; Lopiccolo J; Tsurutani J; Shoemaker RH; Best CJ; Abu-Asab MS; Borojerdi J; Warfel NA; Gardner ER; Danish M; Hollander MC; Kawabata S; Tsokos M; Figg WD; Steeg PS; Dennis PA
Clin Cancer Res; 2007 Sep; 13(17):5183-94. PubMed ID: 17785575
[TBL] [Abstract][Full Text] [Related]
6. Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1.
Chow WA; Guo S; Valdes-Albini F
Anticancer Drugs; 2006 Sep; 17(8):891-903. PubMed ID: 16940799
[TBL] [Abstract][Full Text] [Related]
7. Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis.
Brüning A; Burger P; Vogel M; Rahmeh M; Gingelmaiers A; Friese K; Lenhard M; Burges A
Cancer Biol Ther; 2009 Feb; 8(3):226-32. PubMed ID: 19106637
[TBL] [Abstract][Full Text] [Related]
8. HIV protease inhibitors elicit volume-sensitive Cl- current in cardiac myocytes via mitochondrial ROS.
Deng W; Baki L; Yin J; Zhou H; Baumgarten CM
J Mol Cell Cardiol; 2010 Nov; 49(5):746-52. PubMed ID: 20736017
[TBL] [Abstract][Full Text] [Related]
9. Metformin combined with nelfinavir induces SIRT3/mROS-dependent autophagy in human cervical cancer cells and xenograft in nude mice.
Xia C; He Z; Liang S; Chen R; Xu W; Yang J; Xiao G; Jiang S
Eur J Pharmacol; 2019 Apr; 848():62-69. PubMed ID: 30695683
[TBL] [Abstract][Full Text] [Related]
10. Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells.
Soprano M; Sorriento D; Rusciano MR; Maione AS; Limite G; Forestieri P; D'Angelo D; D'Alessio M; Campiglia P; Formisano P; Iaccarino G; Bianco R; Illario M
PLoS One; 2016; 11(6):e0155970. PubMed ID: 27280849
[TBL] [Abstract][Full Text] [Related]
11. HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir.
Garg H; Blumenthal R
J Leukoc Biol; 2006 Feb; 79(2):351-62. PubMed ID: 16330530
[TBL] [Abstract][Full Text] [Related]
12. Co-treatment With HIV Protease Inhibitor Nelfinavir Greatly Increases Late-phase Apoptosis of Drug-resistant KBV20C Cancer Cells Independently of P-Glycoprotein Inhibition.
Kim JY; Park YJ; Lee BM; Yoon S
Anticancer Res; 2019 Jul; 39(7):3757-3765. PubMed ID: 31262902
[TBL] [Abstract][Full Text] [Related]
13. Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir.
Grigorian A; Hurford R; Chao Y; Patrick C; Langford TD
BMC Neurosci; 2008 Feb; 9():27. PubMed ID: 18302767
[TBL] [Abstract][Full Text] [Related]
14. The HIV protease inhibitor nelfinavir down-regulates RET signaling and induces apoptosis in medullary thyroid cancer cells.
Kushchayeva Y; Jensen K; Recupero A; Costello J; Patel A; Klubo-Gwiezdzinska J; Boyle L; Burman K; Vasko V
J Clin Endocrinol Metab; 2014 May; 99(5):E734-45. PubMed ID: 24483157
[TBL] [Abstract][Full Text] [Related]
15. α-Hederin Induces Apoptosis of Esophageal Squamous Cell Carcinoma via an Oxidative and Mitochondrial-Dependent Pathway.
Wang J; Wu D; Zhang J; Liu H; Wu J; Dong W
Dig Dis Sci; 2019 Dec; 64(12):3528-3538. PubMed ID: 31273592
[TBL] [Abstract][Full Text] [Related]
16. NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines.
Yang Y; Ikezoe T; Nishioka C; Bandobashi K; Takeuchi T; Adachi Y; Kobayashi M; Takeuchi S; Koeffler HP; Taguchi H
Br J Cancer; 2006 Dec; 95(12):1653-62. PubMed ID: 17133272
[TBL] [Abstract][Full Text] [Related]
17. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
Hisatomi T; Nakazawa T; Noda K; Almulki L; Miyahara S; Nakao S; Ito Y; She H; Kohno R; Michaud N; Ishibashi T; Hafezi-Moghadam A; Badley AD; Kroemer G; Miller JW
J Clin Invest; 2008 Jun; 118(6):2025-38. PubMed ID: 18497877
[TBL] [Abstract][Full Text] [Related]
18. Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.
Brüning A; Friese K; Burges A; Mylonas I
Breast Cancer Res; 2010; 12(4):R45. PubMed ID: 20594311
[TBL] [Abstract][Full Text] [Related]
19. Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir.
Shim JS; Rao R; Beebe K; Neckers L; Han I; Nahta R; Liu JO
J Natl Cancer Inst; 2012 Oct; 104(20):1576-90. PubMed ID: 23042933
[TBL] [Abstract][Full Text] [Related]
20. Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib.
Brüning A; Burger P; Vogel M; Gingelmaier A; Friese K; Burges A
Invest New Drugs; 2010 Oct; 28(5):535-42. PubMed ID: 19554262
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
