BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 25938782)

  • 1. BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.
    Basak A; Hancarova M; Ulirsch JC; Balci TB; Trkova M; Pelisek M; Vlckova M; Muzikova K; Cermak J; Trka J; Dyment DA; Orkin SH; Daly MJ; Sedlacek Z; Sankaran VG
    J Clin Invest; 2015 Jun; 125(6):2363-8. PubMed ID: 25938782
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
    Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
    Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptional silencing of fetal hemoglobin by BCL11A.
    Sankaran VG; Xu J; Orkin SH
    Ann N Y Acad Sci; 2010 Aug; 1202():64-8. PubMed ID: 20712774
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment.
    Funnell AP; Prontera P; Ottaviani V; Piccione M; Giambona A; Maggio A; Ciaffoni F; Stehling-Sun S; Marra M; Masiello F; Varricchio L; Stamatoyannopoulos JA; Migliaccio AR; Papayannopoulou T
    Blood; 2015 Jul; 126(1):89-93. PubMed ID: 26019277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polymorphic variations influencing fetal hemoglobin levels: association study in beta-thalassemia carriers and in normal individuals of Portuguese origin.
    Pereira C; Relvas L; Bento C; Abade A; Ribeiro ML; Manco L
    Blood Cells Mol Dis; 2015 Apr; 54(4):315-20. PubMed ID: 25842369
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus.
    Jawaid K; Wahlberg K; Thein SL; Best S
    Blood Cells Mol Dis; 2010 Aug; 45(2):140-6. PubMed ID: 20542454
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.
    Lettre G; Sankaran VG; Bezerra MA; Araújo AS; Uda M; Sanna S; Cao A; Schlessinger D; Costa FF; Hirschhorn JN; Orkin SH
    Proc Natl Acad Sci U S A; 2008 Aug; 105(33):11869-74. PubMed ID: 18667698
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of BCL11A and HMIP-2 polymorphisms on endogenous and hydroxyurea induced levels of fetal hemoglobin in sickle cell anemia patients from southern Brazil.
    Friedrisch JR; Sheehan V; Flanagan JM; Baldan A; Summarell CC; Bittar CM; Friedrisch BK; Wilke II; Ribeiro CB; Daudt LE; da Rocha Silla LM
    Blood Cells Mol Dis; 2016 Nov; 62():32-37. PubMed ID: 27838552
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
    Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
    Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the fetal hemoglobin silencing factor BCL11A.
    Basak A; Sankaran VG
    Ann N Y Acad Sci; 2016 Mar; 1368(1):25-30. PubMed ID: 26963603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Progress on genes related to fetal hemoglobin quantitative trait].
    Guo XQ
    Yi Chuan; 2010 Apr; 32(4):295-300. PubMed ID: 20423883
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies.
    Sedgewick AE; Timofeev N; Sebastiani P; So JCC; Ma ESK; Chan LC; Fucharoen G; Fucharoen S; Barbosa CG; Vardarajan BN; Farrer LA; Baldwin CT; Steinberg MH; Chui DHK
    Blood Cells Mol Dis; 2008; 41(3):255-258. PubMed ID: 18691915
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional polymorphisms of BCL11A and HBS1L-MYB genes affect both fetal hemoglobin level and clinical outcomes in a cohort of children with sickle cell anemia.
    Sales RR; Belisário AR; Faria G; Mendes F; Luizon MR; Viana MB
    Ann Hematol; 2020 Jul; 99(7):1453-1463. PubMed ID: 32447424
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
    Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
    Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
    Uda M; Galanello R; Sanna S; Lettre G; Sankaran VG; Chen W; Usala G; Busonero F; Maschio A; Albai G; Piras MG; Sestu N; Lai S; Dei M; Mulas A; Crisponi L; Naitza S; Asunis I; Deiana M; Nagaraja R; Perseu L; Satta S; Cipollina MD; Sollaino C; Moi P; Hirschhorn JN; Orkin SH; Abecasis GR; Schlessinger D; Cao A
    Proc Natl Acad Sci U S A; 2008 Feb; 105(5):1620-5. PubMed ID: 18245381
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Correlation between hemoglobin F levels and single nucleotide polymorphism at BCL11A gene rs11886868 locus in β-thalassemia patients].
    Chen QR; Sun SC; Peng YS; Wang Q; Mo BM
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2012 Jun; 20(3):650-3. PubMed ID: 22739175
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The XmnI (G)gamma polymorphism influences hemoglobin F synthesis contrary to BCL11A and HBS1L-MYB SNPs in a cohort of 57 beta-thalassemia intermedia patients.
    Nguyen TK; Joly P; Bardel C; Moulsma M; Bonello-Palot N; Francina A
    Blood Cells Mol Dis; 2010 Aug; 45(2):124-7. PubMed ID: 20472475
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Estimation of the difference in HbF expression due to loss of the 5' δ-globin BCL11A binding region.
    Ghedira ES; Lecerf L; Faubert E; Costes B; Moradkhani K; Bachir D; Galactéros F; Pissard S
    Haematologica; 2013 Feb; 98(2):305-8. PubMed ID: 22801970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genetic variant in the BCL11A (rs1427407), but not HBS1-MYB (rs6934903) loci associate with fetal hemoglobin levels in Indian sickle cell disease patients.
    Bhanushali AA; Patra PK; Nair D; Verma H; Das BR
    Blood Cells Mol Dis; 2015 Jan; 54(1):4-8. PubMed ID: 25457385
    [TBL] [Abstract][Full Text] [Related]  

  • 20. rs11886868 and rs4671393 of BCL11A associated with HbF level variation and modulate clinical events among sickle cell anemia patients.
    Chaouch L; Moumni I; Ouragini H; Darragi I; Kalai M; Chaouachi D; Boudrigua I; Hafsia R; Abbes S
    Hematology; 2016 Aug; 21(7):425-9. PubMed ID: 27077760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.