BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

368 related articles for article (PubMed ID: 25939952)

  • 1. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells.
    Zhang L; Wang H; Ding K; Xu J
    Toxicol Lett; 2015 Jul; 236(1):43-59. PubMed ID: 25939952
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways.
    Zhang L; Wang H; Xu J; Zhu J; Ding K
    Toxicol Lett; 2014 Aug; 228(3):248-59. PubMed ID: 24875536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma.
    Estrada-Bernal A; Palanichamy K; Ray Chaudhury A; Van Brocklyn JR
    Neuro Oncol; 2012 Apr; 14(4):405-15. PubMed ID: 22351749
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway.
    Zhang L; Wang H; Zhu J; Ding K; Xu J
    Tumour Biol; 2014 Nov; 35(11):10707-14. PubMed ID: 25070489
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors.
    Kiyota M; Kuroda J; Yamamoto-Sugitani M; Shimura Y; Nakayama R; Nagoshi H; Mizutani S; Chinen Y; Sasaki N; Sakamoto N; Kobayashi T; Matsumoto Y; Horiike S; Taniwaki M
    Apoptosis; 2013 Nov; 18(11):1437-1446. PubMed ID: 23851982
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.
    Saddoughi SA; Gencer S; Peterson YK; Ward KE; Mukhopadhyay A; Oaks J; Bielawski J; Szulc ZM; Thomas RJ; Selvam SP; Senkal CE; Garrett-Mayer E; De Palma RM; Fedarovich D; Liu A; Habib AA; Stahelin RV; Perrotti D; Ogretmen B
    EMBO Mol Med; 2013 Jan; 5(1):105-21. PubMed ID: 23180565
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy.
    Zhang N; Qi Y; Wadham C; Wang L; Warren A; Di W; Xia P
    Autophagy; 2010 Nov; 6(8):1157-67. PubMed ID: 20935520
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy.
    He W; Wang Q; Srinivasan B; Xu J; Padilla MT; Li Z; Wang X; Liu Y; Gou X; Shen HM; Xing C; Lin Y
    Oncogene; 2014 Jun; 33(23):3004-13. PubMed ID: 23831571
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Mechanisms of ROS in U266 cell death induced by FTY720].
    Li YC; Liu ZG; Yao K; Wang HH; Hu R; Yang W; Liao AJ
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2013 Jun; 21(3):643-6. PubMed ID: 23815914
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice.
    Zheng T; Meng X; Wang J; Chen X; Yin D; Liang Y; Song X; Pan S; Jiang H; Liu L
    J Cell Biochem; 2010 Sep; 111(1):218-28. PubMed ID: 20506484
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM; Liu JS; Deng LJ; Chen MF; Yiu A; Cao HH; Tian HY; Fung KP; Kurihara H; Pan JX; Ye WC
    Carcinogenesis; 2013 Jun; 34(6):1331-42. PubMed ID: 23393227
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-neoplastic activity of low-dose endothelial-monocyte activating polypeptide-II results from defective autophagy and G2/M arrest mediated by PI3K/Akt/FoxO1 axis in human glioblastoma stem cells.
    Liu J; Liu L; Xue Y; Meng F; Li S; Wang P; Liu Y
    Biochem Pharmacol; 2014 Jun; 89(4):477-89. PubMed ID: 24792437
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced expression of proapoptotic and autophagic proteins involved in the cell death of glioblastoma induced by synthetic glycans.
    Faried A; Arifin MZ; Ishiuchi S; Kuwano H; Yazawa S
    J Neurosurg; 2014 Jun; 120(6):1298-308. PubMed ID: 24678780
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagy induced by FTY720 promotes apoptosis in U266 cells.
    Liao A; Hu R; Zhao Q; Li J; Li Y; Yao K; Zhang R; Wang H; Yang W; Liu Z
    Eur J Pharm Sci; 2012 Apr; 45(5):600-5. PubMed ID: 22281442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft.
    Ubai T; Azuma H; Kotake Y; Inamoto T; Takahara K; Ito Y; Kiyama S; Sakamoto T; Horie S; Muto S; Takahara S; Otsuki Y; Katsuoka Y
    Anticancer Res; 2007; 27(1A):75-88. PubMed ID: 17352219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Juglanin induces apoptosis and autophagy in human breast cancer progression via ROS/JNK promotion.
    Sun ZL; Dong JL; Wu J
    Biomed Pharmacother; 2017 Jan; 85():303-312. PubMed ID: 27899257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FTY720-induced blockage of autophagy enhances anticancer efficacy of milatuzumab in mantle cell lymphoma: is FTY720 the next autophagy-blocking agent in lymphoma treatment?
    Alinari L; Baiocchi RA; Praetorius-Ibba M
    Autophagy; 2012 Mar; 8(3):416-7. PubMed ID: 22377620
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.
    Xie CM; Chan WY; Yu S; Zhao J; Cheng CH
    Free Radic Biol Med; 2011 Oct; 51(7):1365-75. PubMed ID: 21763418
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma.
    Omar HA; Chou CC; Berman-Booty LD; Ma Y; Hung JH; Wang D; Kogure T; Patel T; Terracciano L; Muthusamy N; Byrd JC; Kulp SK; Chen CS
    Hepatology; 2011 Jun; 53(6):1943-58. PubMed ID: 21391227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.
    Hung JH; Lu YS; Wang YC; Ma YH; Wang DS; Kulp SK; Muthusamy N; Byrd JC; Cheng AL; Chen CS
    Cancer Res; 2008 Feb; 68(4):1204-12. PubMed ID: 18281497
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.