BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 25940823)

  • 1. Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.
    de Vries Schultink AH; Zwart W; Linn SC; Beijnen JH; Huitema AD
    Clin Pharmacokinet; 2015 Aug; 54(8):797-810. PubMed ID: 25940823
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Individualization of tamoxifen therapy: much more than just CYP2D6 genotyping.
    Binkhorst L; Mathijssen RH; Jager A; van Gelder T
    Cancer Treat Rev; 2015 Mar; 41(3):289-99. PubMed ID: 25618289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multigene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19, and ABCB1.
    Powers JL; Buys SS; Fletcher D; Melis R; Johnson-Davis KL; Lyon E; Malmberg EM; McMillin GA
    J Clin Pharmacol; 2016 Dec; 56(12):1570-1581. PubMed ID: 27198207
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes.
    Schroth W; Antoniadou L; Fritz P; Schwab M; Muerdter T; Zanger UM; Simon W; Eichelbaum M; Brauch H
    J Clin Oncol; 2007 Nov; 25(33):5187-93. PubMed ID: 18024866
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Advances in the research of pharmacogenomics of tamoxifen].
    Xiong W; Zhao JJ; Wang L; Jiang XH; Tao XQ
    Yao Xue Xue Bao; 2016 Sep; 51(9):1356-67. PubMed ID: 29924509
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tailored Tamoxifen Treatment for Breast Cancer Patients: A Perspective.
    Jager NG; Linn SC; Schellens JH; Beijnen JH
    Clin Breast Cancer; 2015 Aug; 15(4):241-4. PubMed ID: 25997856
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploiting Pharmacokinetic Models of Tamoxifen and Endoxifen to Identify Factors Causing Subtherapeutic Concentrations in Breast Cancer Patients.
    Klopp-Schulze L; Joerger M; Wicha SG; Ter Heine R; Csajka C; Parra-Guillen ZP; Kloft C
    Clin Pharmacokinet; 2018 Feb; 57(2):229-242. PubMed ID: 28540639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tamoxifen pharmacokinetics and pharmacodynamics in older patients with non-metastatic breast cancer.
    Souwer ETD; Sanchez-Spitman A; Moes DJAR; Gelderblom H; Swen JJ; Portielje JEA; Guchelaar HJ; van Gelder T
    Breast Cancer Res Treat; 2023 Jun; 199(3):471-478. PubMed ID: 37067610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
    Kiyotani K; Mushiroda T; Zembutsu H; Nakamura Y
    J Hum Genet; 2013 Jun; 58(6):327-33. PubMed ID: 23657426
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes.
    Singh MS; Francis PA; Michael M
    Breast; 2011 Apr; 20(2):111-8. PubMed ID: 21185724
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.
    Lim YC; Desta Z; Flockhart DA; Skaar TC
    Cancer Chemother Pharmacol; 2005 May; 55(5):471-8. PubMed ID: 15685451
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Ahmed JH; Makonnen E; Fotoohi A; Aseffa A; Howe R; Aklillu E
    Cancers (Basel); 2019 Sep; 11(9):. PubMed ID: 31547390
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome.
    de Vries Schultink AH; Alexi X; van Werkhoven E; Madlensky L; Natarajan L; Flatt SW; Zwart W; Linn SC; Parker BA; Wu AH; Pierce JP; Huitema AD; Beijnen JH
    Breast Cancer Res Treat; 2017 Feb; 161(3):567-574. PubMed ID: 28005246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters.
    Kiyotani K; Mushiroda T; Nakamura Y; Zembutsu H
    Drug Metab Pharmacokinet; 2012; 27(1):122-31. PubMed ID: 22041137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Personalized medicine in breast cancer: tamoxifen, endoxifen, and CYP2D6 in clinical practice.
    Ruddy KJ; Desantis SD; Gelman RS; Wu AH; Punglia RS; Mayer EL; Tolaney SM; Winer EP; Partridge AH; Burstein HJ
    Breast Cancer Res Treat; 2013 Oct; 141(3):421-7. PubMed ID: 24062210
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen therapy.
    Mwinyi J; Vokinger K; Jetter A; Breitenstein U; Hiller C; Kullak-Ublick GA; Trojan A
    Cancer Chemother Pharmacol; 2014 Jun; 73(6):1181-8. PubMed ID: 24682508
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired tamoxifen metabolism reduces survival in familial breast cancer patients.
    Newman WG; Hadfield KD; Latif A; Roberts SA; Shenton A; McHague C; Lalloo F; Howell S; Evans DG
    Clin Cancer Res; 2008 Sep; 14(18):5913-8. PubMed ID: 18794105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment.
    de Graan AJ; Teunissen SF; de Vos FY; Loos WJ; van Schaik RH; de Jongh FE; de Vos AI; van Alphen RJ; van der Holt B; Verweij J; Seynaeve C; Beijnen JH; Mathijssen RH
    J Clin Oncol; 2011 Aug; 29(24):3240-6. PubMed ID: 21768449
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen.
    Johnson MD; Zuo H; Lee KH; Trebley JP; Rae JM; Weatherman RV; Desta Z; Flockhart DA; Skaar TC
    Breast Cancer Res Treat; 2004 May; 85(2):151-9. PubMed ID: 15111773
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment.
    Borges S; Desta Z; Li L; Skaar TC; Ward BA; Nguyen A; Jin Y; Storniolo AM; Nikoloff DM; Wu L; Hillman G; Hayes DF; Stearns V; Flockhart DA
    Clin Pharmacol Ther; 2006 Jul; 80(1):61-74. PubMed ID: 16815318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.