151 related articles for article (PubMed ID: 25951139)
1. Discovery of Novel Liver-Stage Antimalarials through Quantum Similarity.
Sullivan DJ; Liu Y; Mott BT; Kaludov N; Martinov MN
PLoS One; 2015; 10(5):e0125593. PubMed ID: 25951139
[TBL] [Abstract][Full Text] [Related]
2. 3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.
Das U; Singh RS; Alcorn J; Hickman MR; Sciotti RJ; Leed SE; Lee PJ; Roncal N; Dimmock JR
Bioorg Med Chem; 2013 Dec; 21(23):7250-6. PubMed ID: 24139941
[TBL] [Abstract][Full Text] [Related]
3. Mapping antimalarial pharmacophores as a useful tool for the rapid discovery of drugs effective in vivo: design, construction, characterization, and pharmacology of metaquine.
Dascombe MJ; Drew MG; Morris H; Wilairat P; Auparakkitanon S; Moule WA; Alizadeh-Shekalgourabi S; Evans PG; Lloyd M; Dyas AM; Carr P; Ismail FM
J Med Chem; 2005 Aug; 48(17):5423-36. PubMed ID: 16107142
[TBL] [Abstract][Full Text] [Related]
4. Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.
Rodrigues T; da Cruz FP; Lafuente-Monasterio MJ; Gonçalves D; Ressurreição AS; Sitoe AR; Bronze MR; Gut J; Schneider G; Mota MM; Rosenthal PJ; Prudêncio M; Gamo FJ; Lopes F; Moreira R
J Med Chem; 2013 Jun; 56(11):4811-5. PubMed ID: 23701465
[TBL] [Abstract][Full Text] [Related]
5. New quinoline derivatives demonstrate a promising antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
Soares RR; da Silva JM; Carlos BC; da Fonseca CC; de Souza LS; Lopes FV; de Paula Dias RM; Moreira PO; Abramo C; Viana GH; de Pila Varotti F; da Silva AD; Scopel KK
Bioorg Med Chem Lett; 2015 Jun; 25(11):2308-13. PubMed ID: 25920564
[TBL] [Abstract][Full Text] [Related]
6. Targeting the erythrocytic and liver stages of malaria parasites with s-triazine-based hybrids.
Rodrigues CA; Frade RF; Albuquerque IS; Perry MJ; Gut J; Machado M; Rosenthal PJ; Prudêncio M; Afonso CA; Moreira R
ChemMedChem; 2015 May; 10(5):883-90. PubMed ID: 25784585
[TBL] [Abstract][Full Text] [Related]
7. Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting
Arez F; Rebelo SP; Fontinha D; Simão D; Martins TR; Machado M; Fischli C; Oeuvray C; Badolo L; Carrondo MJT; Rottmann M; Spangenberg T; Brito C; Greco B; Prudêncio M; Alves PM
ACS Infect Dis; 2019 Nov; 5(11):1831-1842. PubMed ID: 31479238
[TBL] [Abstract][Full Text] [Related]
8. A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.
Le Manach C; Paquet T; Brunschwig C; Njoroge M; Han Z; Gonzàlez Cabrera D; Bashyam S; Dhinakaran R; Taylor D; Reader J; Botha M; Churchyard A; Lauterbach S; Coetzer TL; Birkholtz LM; Meister S; Winzeler EA; Waterson D; Witty MJ; Wittlin S; Jiménez-Díaz MB; Santos Martínez M; Ferrer S; Angulo-Barturen I; Street LJ; Chibale K
J Med Chem; 2015 Nov; 58(21):8713-22. PubMed ID: 26502160
[TBL] [Abstract][Full Text] [Related]
9. A plant-derived morphinan as a novel lead compound active against malaria liver stages.
Carraz M; Jossang A; Franetich JF; Siau A; Ciceron L; Hannoun L; Sauerwein R; Frappier F; Rasoanaivo P; Snounou G; Mazier D
PLoS Med; 2006 Dec; 3(12):e513. PubMed ID: 17194195
[TBL] [Abstract][Full Text] [Related]
10. Malaria-infected mice are cured by oral administration of new artemisinin derivatives.
Posner GH; Chang W; Hess L; Woodard L; Sinishtaj S; Usera AR; Maio W; Rosenthal AS; Kalinda AS; D'Angelo JG; Petersen KS; Stohler R; Chollet J; Santo-Tomas J; Snyder C; Rottmann M; Wittlin S; Brun R; Shapiro TA
J Med Chem; 2008 Feb; 51(4):1035-42. PubMed ID: 18232653
[TBL] [Abstract][Full Text] [Related]
11. Metabolites of febrifugine and its synthetic analogue by mouse liver S9 and their antimalarial activity against Plasmodium malaria parasite.
Hirai S; Kikuchi H; Kim HS; Begum K; Wataya Y; Tasaka H; Miyazawa Y; Yamamoto K; Oshima Y
J Med Chem; 2003 Sep; 46(20):4351-9. PubMed ID: 13678413
[TBL] [Abstract][Full Text] [Related]
12. Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials.
Araújo MJ; Bom J; Capela R; Casimiro C; Chambel P; Gomes P; Iley J; Lopes F; Morais J; Moreira R; de Oliveira E; do Rosário V; Vale N
J Med Chem; 2005 Feb; 48(3):888-92. PubMed ID: 15689174
[TBL] [Abstract][Full Text] [Related]
13. Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
Malmquist NA; Sundriyal S; Caron J; Chen P; Witkowski B; Menard D; Suwanarusk R; Renia L; Nosten F; Jiménez-Díaz MB; Angulo-Barturen I; Santos Martínez M; Ferrer S; Sanz LM; Gamo FJ; Wittlin S; Duffy S; Avery VM; Ruecker A; Delves MJ; Sinden RE; Fuchter MJ; Scherf A
Antimicrob Agents Chemother; 2015 Feb; 59(2):950-9. PubMed ID: 25421480
[TBL] [Abstract][Full Text] [Related]
14. Flavones as isosteres of 4(1H)-quinolones: discovery of ligand efficient and dual stage antimalarial lead compounds.
Rodrigues T; Ressurreição AS; da Cruz FP; Albuquerque IS; Gut J; Carrasco MP; Gonçalves D; Guedes RC; dos Santos DJ; Mota MM; Rosenthal PJ; Moreira R; Prudêncio M; Lopes F
Eur J Med Chem; 2013 Nov; 69():872-80. PubMed ID: 24125849
[TBL] [Abstract][Full Text] [Related]
15. Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
Ghosh S; Chan JM; Lea CR; Meints GA; Lewis JC; Tovian ZS; Flessner RM; Loftus TC; Bruchhaus I; Kendrick H; Croft SL; Kemp RG; Kobayashi S; Nozaki T; Oldfield E
J Med Chem; 2004 Jan; 47(1):175-87. PubMed ID: 14695831
[TBL] [Abstract][Full Text] [Related]
16. A primaquine-chloroquine hybrid with dual activity against Plasmodium liver and blood stages.
Lödige M; Lewis MD; Paulsen ES; Esch HL; Pradel G; Lehmann L; Brun R; Bringmann G; Mueller AK
Int J Med Microbiol; 2013 Dec; 303(8):539-47. PubMed ID: 23992634
[TBL] [Abstract][Full Text] [Related]
17. Tetraoxanes: synthetic and medicinal chemistry perspective.
Kumar N; Singh R; Rawat DS
Med Res Rev; 2012 May; 32(3):581-610. PubMed ID: 22675731
[TBL] [Abstract][Full Text] [Related]
18. N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.
Ramachandran S; Hameed P S; Srivastava A; Shanbhag G; Morayya S; Rautela N; Awasthy D; Kavanagh S; Bharath S; Reddy J; Panduga V; Prabhakar KR; Saralaya R; Nanduri R; Raichurkar A; Menasinakai S; Achar V; Jiménez-Díaz MB; Martínez MS; Angulo-Barturen I; Ferrer S; Sanz LM; Gamo FJ; Duffy S; Avery VM; Waterson D; Lee MC; Coburn-Flynn O; Fidock DA; Iyer PS; Narayanan S; Hosagrahara V; Sambandamurthy VK
J Med Chem; 2014 Aug; 57(15):6642-52. PubMed ID: 25007124
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and antimalarial property of orally active phenoxazinium salts.
Takasu K; Shimogama T; Satoh C; Kaiser M; Brun R; Ihara M
J Med Chem; 2007 May; 50(10):2281-4. PubMed ID: 17441706
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of alpha-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials.
Verbrugghen T; Cos P; Maes L; Van Calenbergh S
J Med Chem; 2010 Jul; 53(14):5342-6. PubMed ID: 20568776
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
