These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Pleckstrin homology (PH) domain and Leucine Rich Repeat Phosphatase 1 (Phlpp1) Suppresses Parathyroid Hormone Receptor 1 (Pth1r) Expression and Signaling During Bone Growth. Weaver SR; Taylor EL; Zars EL; Arnold KM; Bradley EW; Westendorf JJ J Bone Miner Res; 2021 May; 36(5):986-999. PubMed ID: 33434347 [TBL] [Abstract][Full Text] [Related]
5. Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice. Mattson AM; Begun DL; Molstad DHH; Meyer MA; Oursler MJ; Westendorf JJ; Bradley EW J Biol Chem; 2019 Aug; 294(31):11772-11784. PubMed ID: 31189651 [TBL] [Abstract][Full Text] [Related]
6. DNA methylation and FoxO3a regulate PHLPP1 expression in chondrocytes. Castillejo Becerra CM; Mattson AM; Molstad DHH; Lorang IM; Westendorf JJ; Bradley EW J Cell Biochem; 2018 Sep; 119(9):7470-7478. PubMed ID: 29775231 [TBL] [Abstract][Full Text] [Related]
7. PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice. Li X; Stevens PD; Liu J; Yang H; Wang W; Wang C; Zeng Z; Schmidt MD; Yang M; Lee EY; Gao T Gastroenterology; 2014 May; 146(5):1301-12.e1-10. PubMed ID: 24530606 [TBL] [Abstract][Full Text] [Related]
8. PHLPP1 gene deletion protects the brain from ischemic injury. Chen B; Van Winkle JA; Lyden PD; Brown JH; Purcell NH J Cereb Blood Flow Metab; 2013 Feb; 33(2):196-204. PubMed ID: 23072745 [TBL] [Abstract][Full Text] [Related]
9. Myeloid Lineage Ablation of Karkache IY; Damodaran JR; Molstad DHH; Mansky KC; Bradley EW Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34575866 [TBL] [Abstract][Full Text] [Related]
10. NFκB1 (p50) suppresses SOD2 expression by inhibiting FoxO3a transactivation in a miR190/PHLPP1/Akt-dependent axis. Du K; Yu Y; Zhang D; Luo W; Huang H; Chen J; Gao J; Huang C Mol Biol Cell; 2013 Nov; 24(22):3577-83. PubMed ID: 24068327 [TBL] [Abstract][Full Text] [Related]
11. Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy. Moc C; Taylor AE; Chesini GP; Zambrano CM; Barlow MS; Zhang X; Gustafsson ÅB; Purcell NH Cardiovasc Res; 2015 Feb; 105(2):160-70. PubMed ID: 25411382 [TBL] [Abstract][Full Text] [Related]
12. PHLPPing through history: a decade in the life of PHLPP phosphatases. Grzechnik AT; Newton AC Biochem Soc Trans; 2016 Dec; 44(6):1675-1682. PubMed ID: 27913677 [TBL] [Abstract][Full Text] [Related]
13. Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells. Patterson SJ; Han JM; Garcia R; Assi K; Gao T; O'Neill A; Newton AC; Levings MK J Immunol; 2011 May; 186(10):5533-7. PubMed ID: 21498666 [TBL] [Abstract][Full Text] [Related]
15. WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1). Gangula NR; Maddika S J Biol Chem; 2013 Nov; 288(48):34545-54. PubMed ID: 24145035 [TBL] [Abstract][Full Text] [Related]
16. Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. Zhang C; Smith MP; Zhou GK; Lai A; Hoy RC; Mroz V; Torre OM; Laudier DM; Bradley EW; Westendorf JJ; Iatridis JC; Illien-Jünger S Cell Death Dis; 2019 Oct; 10(10):754. PubMed ID: 31582730 [TBL] [Abstract][Full Text] [Related]
17. PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum. Saavedra A; García-Martínez JM; Xifró X; Giralt A; Torres-Peraza JF; Canals JM; Díaz-Hernández M; Lucas JJ; Alberch J; Pérez-Navarro E Cell Death Differ; 2010 Feb; 17(2):324-35. PubMed ID: 19745829 [TBL] [Abstract][Full Text] [Related]
18. Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt. Warfel NA; Niederst M; Stevens MW; Brennan PM; Frame MC; Newton AC J Biol Chem; 2011 Jun; 286(22):19777-88. PubMed ID: 21454620 [TBL] [Abstract][Full Text] [Related]
19. RasGAP Shields Akt from Deactivating Phosphatases in Fibroblast Growth Factor Signaling but Loses This Ability Once Cleaved by Caspase-3. Cailliau K; Lescuyer A; Burnol AF; Cuesta-Marbán Á; Widmann C; Browaeys-Poly E J Biol Chem; 2015 Aug; 290(32):19653-65. PubMed ID: 26109071 [TBL] [Abstract][Full Text] [Related]
20. Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling. Warfel NA; Newton AC J Biol Chem; 2012 Feb; 287(6):3610-6. PubMed ID: 22144674 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]