476 related articles for article (PubMed ID: 25958115)
1. Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.
Hochgräfe K; Sydow A; Matenia D; Cadinu D; Könen S; Petrova O; Pickhardt M; Goll P; Morellini F; Mandelkow E; Mandelkow EM
Acta Neuropathol Commun; 2015 May; 3():25. PubMed ID: 25958115
[TBL] [Abstract][Full Text] [Related]
2. Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy.
Anglada-Huguet M; Endepols H; Sydow A; Hilgers R; Neumaier B; Drzezga A; Kaniyappan S; Mandelkow E; Mandelkow EM
Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298211
[TBL] [Abstract][Full Text] [Related]
3. Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.
Van der Jeugd A; Hochgräfe K; Ahmed T; Decker JM; Sydow A; Hofmann A; Wu D; Messing L; Balschun D; D'Hooge R; Mandelkow EM
Acta Neuropathol; 2012 Jun; 123(6):787-805. PubMed ID: 22532069
[TBL] [Abstract][Full Text] [Related]
4. Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer's disease mouse model.
Green C; Sydow A; Vogel S; Anglada-Huguet M; Wiedermann D; Mandelkow E; Mandelkow EM; Hoehn M
Mol Neurodegener; 2019 Mar; 14(1):13. PubMed ID: 30917861
[TBL] [Abstract][Full Text] [Related]
5. Regulatable transgenic mouse models of Alzheimer disease: onset, reversibility and spreading of Tau pathology.
Hochgräfe K; Sydow A; Mandelkow EM
FEBS J; 2013 Sep; 280(18):4371-81. PubMed ID: 23517246
[TBL] [Abstract][Full Text] [Related]
6. Spreading of Tau Protein Does Not Depend on Aggregation Propensity.
Rodrigues S; Anglada-Huguet M; Hochgräfe K; Kaniyappan S; Wegmann S; Mandelkow EM
J Mol Neurosci; 2023 Oct; 73(9-10):693-712. PubMed ID: 37606769
[TBL] [Abstract][Full Text] [Related]
7. Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant.
Sydow A; Van der Jeugd A; Zheng F; Ahmed T; Balschun D; Petrova O; Drexler D; Zhou L; Rune G; Mandelkow E; D'Hooge R; Alzheimer C; Mandelkow EM
J Neurosci; 2011 Feb; 31(7):2511-25. PubMed ID: 21325519
[TBL] [Abstract][Full Text] [Related]
8. Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.
Chalermpalanupap T; Schroeder JP; Rorabaugh JM; Liles LC; Lah JJ; Levey AI; Weinshenker D
J Neurosci; 2018 Jan; 38(1):74-92. PubMed ID: 29133432
[TBL] [Abstract][Full Text] [Related]
9. Memory deficits correlate with tau and spine pathology in P301S MAPT transgenic mice.
Xu H; Rösler TW; Carlsson T; de Andrade A; Bruch J; Höllerhage M; Oertel WH; Höglinger GU
Neuropathol Appl Neurobiol; 2014 Dec; 40(7):833-43. PubMed ID: 24865638
[TBL] [Abstract][Full Text] [Related]
10. High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration.
Wheeler JM; McMillan PJ; Hawk M; Iba M; Robinson L; Xu GJ; Dombroski BA; Jeong D; Dichter MA; Juul H; Loomis E; Raskind M; Leverenz JB; Trojanowski JQ; Lee VM; Schellenberg GD; Kraemer BC
Acta Neuropathol Commun; 2015 Jun; 3():33. PubMed ID: 26041339
[TBL] [Abstract][Full Text] [Related]
11. Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027.
Barten DM; Fanara P; Andorfer C; Hoque N; Wong PY; Husted KH; Cadelina GW; Decarr LB; Yang L; Liu V; Fessler C; Protassio J; Riff T; Turner H; Janus CG; Sankaranarayanan S; Polson C; Meredith JE; Gray G; Hanna A; Olson RE; Kim SH; Vite GD; Lee FY; Albright CF
J Neurosci; 2012 May; 32(21):7137-45. PubMed ID: 22623658
[TBL] [Abstract][Full Text] [Related]
12. A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer's disease.
Onishi T; Iwashita H; Uno Y; Kunitomo J; Saitoh M; Kimura E; Fujita H; Uchiyama N; Kori M; Takizawa M
J Neurochem; 2011 Dec; 119(6):1330-40. PubMed ID: 21992552
[TBL] [Abstract][Full Text] [Related]
13. Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.
Stack C; Jainuddin S; Elipenahli C; Gerges M; Starkova N; Starkov AA; Jové M; Portero-Otin M; Launay N; Pujol A; Kaidery NA; Thomas B; Tampellini D; Beal MF; Dumont M
Hum Mol Genet; 2014 Jul; 23(14):3716-32. PubMed ID: 24556215
[TBL] [Abstract][Full Text] [Related]
14. Analysis of in vivo turnover of tau in a mouse model of tauopathy.
Yamada K; Patel TK; Hochgräfe K; Mahan TE; Jiang H; Stewart FR; Mandelkow EM; Holtzman DM
Mol Neurodegener; 2015 Oct; 10():55. PubMed ID: 26502977
[TBL] [Abstract][Full Text] [Related]
15. Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model.
Sydow A; Van der Jeugd A; Zheng F; Ahmed T; Balschun D; Petrova O; Drexler D; Zhou L; Rune G; Mandelkow E; D'Hooge R; Alzheimer C; Mandelkow EM
J Mol Neurosci; 2011 Nov; 45(3):432-7. PubMed ID: 21822709
[TBL] [Abstract][Full Text] [Related]
16. Resveratrol Rescues Tau-Induced Cognitive Deficits and Neuropathology in a Mouse Model of Tauopathy.
Sun XY; Dong QX; Zhu J; Sun X; Zhang LF; Qiu M; Yu XL; Liu RT
Curr Alzheimer Res; 2019; 16(8):710-722. PubMed ID: 31368873
[TBL] [Abstract][Full Text] [Related]
17. Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.
Green KN; Steffan JS; Martinez-Coria H; Sun X; Schreiber SS; Thompson LM; LaFerla FM
J Neurosci; 2008 Nov; 28(45):11500-10. PubMed ID: 18987186
[TBL] [Abstract][Full Text] [Related]
18. Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance.
Jiang T; Yu JT; Zhu XC; Zhang QQ; Cao L; Wang HF; Tan MS; Gao Q; Qin H; Zhang YD; Tan L
Neuropharmacology; 2014 Oct; 85():121-30. PubMed ID: 24880087
[TBL] [Abstract][Full Text] [Related]
19. Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression.
Hunsberger HC; Weitzner DS; Rudy CC; Hickman JE; Libell EM; Speer RR; Gerhardt GA; Reed MN
J Neurochem; 2015 Oct; 135(2):381-94. PubMed ID: 26146790
[TBL] [Abstract][Full Text] [Related]
20. A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.
Rosenmann H; Grigoriadis N; Eldar-Levy H; Avital A; Rozenstein L; Touloumi O; Behar L; Ben-Hur T; Avraham Y; Berry E; Segal M; Ginzburg I; Abramsky O
Exp Neurol; 2008 Jul; 212(1):71-84. PubMed ID: 18490011
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]