BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 25958399)

  • 1. Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.
    Kellermann G; Kaiser M; Dingli F; Lahuna O; Naud-Martin D; Mahuteau-Betzer F; Loew D; Ségal-Bendirdjian E; Teulade-Fichou MP; Bombard S
    Nucleic Acids Res; 2015 Sep; 43(15):e99. PubMed ID: 25958399
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template.
    Zemora G; Handl S; Waldsich C
    Nucleic Acids Res; 2016 Jan; 44(1):413-25. PubMed ID: 26481359
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of hTERT and hTR in cis reconstitutes and active human telomerase ribonucleoprotein.
    Bachand F; Kukolj G; Autexier C
    RNA; 2000 May; 6(5):778-84. PubMed ID: 10836798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of telomerase activity by preventing proper assemblage.
    Keppler BR; Jarstfer MB
    Biochemistry; 2004 Jan; 43(2):334-43. PubMed ID: 14717587
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae.
    Bachand F; Autexier C
    J Biol Chem; 1999 Dec; 274(53):38027-31. PubMed ID: 10608871
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting to the endoplasmic reticulum improves the folding of recombinant human telomerase reverse transcriptase.
    Wu CK; Gousset K; Hughes SH
    Protein Expr Purif; 2007 Nov; 56(1):8-19. PubMed ID: 17658270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Telomerase reverse transcriptase (hTERT) mRNA and telomerase RNA (hTR) as targets for downregulation of telomerase activity.
    Natarajan S; Chen Z; Wancewicz EV; Monia BP; Corey DR
    Oligonucleotides; 2004; 14(4):263-73. PubMed ID: 15665594
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exploring the mechanism of inhibition of human telomerase by cysteine-reactive compounds.
    Kellermann G; Dingli F; Masson V; Dauzonne D; Ségal-Bendirdjian E; Teulade-Fichou MP; Loew D; Bombard S
    FEBS Lett; 2017 Mar; 591(6):863-874. PubMed ID: 28186330
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein.
    Stone MD; Mihalusova M; O'connor CM; Prathapam R; Collins K; Zhuang X
    Nature; 2007 Mar; 446(7134):458-61. PubMed ID: 17322903
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A high-throughput assay for a human telomerase protein-human telomerase RNA interaction.
    Keppler BR; Jarstfer MB
    Anal Biochem; 2006 Jun; 353(1):75-82. PubMed ID: 16620757
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions.
    Bachand F; Autexier C
    Mol Cell Biol; 2001 Mar; 21(5):1888-97. PubMed ID: 11238925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro.
    Tesmer VM; Ford LP; Holt SE; Frank BC; Yi X; Aisner DL; Ouellette M; Shay JW; Wright WE
    Mol Cell Biol; 1999 Sep; 19(9):6207-16. PubMed ID: 10454567
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT.
    Xi L; Cech TR
    Nucleic Acids Res; 2014 Jul; 42(13):8565-77. PubMed ID: 24990373
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells.
    Hayashidani Y; Hiyama E; Murakami Y; Sueda T
    Hiroshima J Med Sci; 2005 Mar; 54(1):21-7. PubMed ID: 15847061
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNA conformation in catalytically active human telomerase.
    Yeoman JA; Orte A; Ashbridge B; Klenerman D; Balasubramanian S
    J Am Chem Soc; 2010 Mar; 132(9):2852-3. PubMed ID: 20148555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
    Goldkorn A; Blackburn EH
    Cancer Res; 2006 Jun; 66(11):5763-71. PubMed ID: 16740715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small-molecule-based identification of dynamic assembly of E2F-pocket protein-histone deacetylase complex for telomerase regulation in human cells.
    Won J; Chang S; Oh S; Kim TK
    Proc Natl Acad Sci U S A; 2004 Aug; 101(31):11328-33. PubMed ID: 15263087
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity.
    Cairney CJ; Keith WN
    Biochimie; 2008 Jan; 90(1):13-23. PubMed ID: 17854971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Telomerase repeat amplification protocol (TRAP) activity upon recombinant expression and purification of human telomerase in a bacterial system.
    Hansen DT; Thiyagarajan T; Larson AC; Hansen JL
    Protein Expr Purif; 2016 Jul; 123():6-13. PubMed ID: 26965413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase.
    Dominick PK; Keppler BR; Legassie JD; Moon IK; Jarstfer MB
    Bioorg Med Chem Lett; 2004 Jul; 14(13):3467-71. PubMed ID: 15177454
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.