BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 25960230)

  • 1. Use of ligand-based pharmacophore modeling and docking approach to find novel acetylcholinesterase inhibitors for treating Alzheimer's.
    Dhanjal JK; Sharma S; Grover A; Das A
    Biomed Pharmacother; 2015 Apr; 71():146-52. PubMed ID: 25960230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacophore mapping-based virtual screening followed by molecular docking studies in search of potential acetylcholinesterase inhibitors as anti-Alzheimer's agents.
    Ambure P; Kar S; Roy K
    Biosystems; 2014 Feb; 116():10-20. PubMed ID: 24325852
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer's Disease.
    Son M; Park C; Rampogu S; Zeb A; Lee KW
    Int J Mol Sci; 2019 Feb; 20(4):. PubMed ID: 30823604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacophore Modeling, virtual and in vitro screening for acetylcholinesterase inhibitors and their effects on amyloid-β self- assembly.
    Bag S; Tulsan R; Sood A; Datta S; Török M
    Curr Comput Aided Drug Des; 2013 Mar; 9(1):2-14. PubMed ID: 22734711
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Virtual screening, molecular interaction field, molecular dynamics, docking, density functional, and ADMET properties of novel AChE inhibitors in Alzheimer's disease.
    da Silva CH; Carvalho I; Taft CA
    J Biomol Struct Dyn; 2007 Jun; 24(6):515-24. PubMed ID: 17508773
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico design and search for acetylcholinesterase inhibitors in Alzheimer's disease with a suitable pharmacokinetic profile and low toxicity.
    da Silva VB; de Andrade P; Kawano DF; Morais PA; de Almeida JR; Carvalho I; Taft CA; da Silva CH
    Future Med Chem; 2011 Jun; 3(8):947-60. PubMed ID: 21707398
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantifying ligand-receptor interactions for gorge-spanning acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Martis EA; Chandarana RC; Shaikh MS; Ambre PK; D'Souza JS; Iyer KR; Coutinho EC; Nandan SR; Pissurlenkar RR
    J Biomol Struct Dyn; 2015; 33(5):1107-25. PubMed ID: 24905476
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acetylcholinesterase inhibitors: structure based design, synthesis, pharmacophore modeling, and virtual screening.
    Valasani KR; Chaney MO; Day VW; Shidu Yan S
    J Chem Inf Model; 2013 Aug; 53(8):2033-46. PubMed ID: 23777291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Designing Second Generation Anti-Alzheimer Compounds as Inhibitors of Human Acetylcholinesterase: Computational Screening of Synthetic Molecules and Dietary Phytochemicals.
    Amat-Ur-Rasool H; Ahmed M
    PLoS One; 2015; 10(9):e0136509. PubMed ID: 26325402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of potential bivalent inhibitors from natural compounds for acetylcholinesterase through in silico screening using multiple pharmacophores.
    Lakshmi V; Kannan VS; Boopathy R
    J Mol Graph Model; 2013 Mar; 40():72-9. PubMed ID: 23353586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined 3D-QSAR, molecular docking, and molecular dynamics study of tacrine derivatives as potential acetylcholinesterase (AChE) inhibitors of Alzheimer's disease.
    Zhou A; Hu J; Wang L; Zhong G; Pan J; Wu Z; Hui A
    J Mol Model; 2015 Oct; 21(10):277. PubMed ID: 26438408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High throughput virtual screening and E-pharmacophore filtering in the discovery of new BACE-1 inhibitors.
    Muthusamy K; Singh KhD; Chinnasamy S; Nagamani S; Krishnasamy G; Thiyagarajan C; Premkumar P; Anusuyadevi M
    Interdiscip Sci; 2013 Jun; 5(2):119-26. PubMed ID: 23740393
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In silico Structure-based Identification of Novel Acetylcholinesterase Inhibitors Against Alzheimer's Disease.
    Iman K; Mirza MU; Mazhar N; Vanmeert M; Irshad I; Kamal MA
    CNS Neurol Disord Drug Targets; 2018 Apr; 17(1):54-68. PubMed ID: 29336270
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of potential PKC inhibitors through pharmacophore designing, 3D-QSAR and molecular dynamics simulations targeting Alzheimer's disease.
    Iqbal S; Anantha Krishnan D; Gunasekaran K
    J Biomol Struct Dyn; 2018 Nov; 36(15):4029-4044. PubMed ID: 29182053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of molecular descriptors for design of novel Isoalloxazine derivatives as potential Acetylcholinesterase inhibitors against Alzheimer's disease.
    Gurung AB; Aguan K; Mitra S; Bhattacharjee A
    J Biomol Struct Dyn; 2017 Jun; 35(8):1729-1742. PubMed ID: 27410776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. De-novo Drug Design, Molecular Docking and In-Silico Molecular Prediction of AChEI Analogues through CADD Approaches as Anti-Alzheimer's Agents.
    Pandey S; Singh BK
    Curr Comput Aided Drug Des; 2020; 16(1):54-72. PubMed ID: 30827255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of dual binding site acetylcholinesterase inhibitors identified by pharmacophore modeling and sequential virtual screening techniques.
    Gupta S; Fallarero A; Järvinen P; Karlsson D; Johnson MS; Vuorela PM; Mohan CG
    Bioorg Med Chem Lett; 2011 Feb; 21(4):1105-12. PubMed ID: 21273074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
    Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel Potent and Selective Acetylcholinesterase Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease: Synthesis, Pharmacological Evaluation, and Molecular Modeling of Amino-Alkyl-Substituted Fluoro-Chalcones Derivatives.
    Liu HR; Zhou C; Fan HQ; Tang JJ; Liu LB; Gao XH; Wang QA; Liu WK
    Chem Biol Drug Des; 2015 Oct; 86(4):517-22. PubMed ID: 25588967
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.
    Meena P; Nemaysh V; Khatri M; Manral A; Luthra PM; Tiwari M
    Bioorg Med Chem; 2015 Mar; 23(5):1135-48. PubMed ID: 25624107
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.