BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 25965993)

  • 1. Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.
    Stulemeijer IJ; De Vos D; van Harten K; Joshi OK; Blomberg O; van Welsem T; Terweij M; Vlaming H; de Graaf EL; Altelaar AF; Bakker BM; van Leeuwen F
    Sci Rep; 2015 May; 5():9824. PubMed ID: 25965993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.
    Frederiks F; van Welsem T; Oudgenoeg G; Heck AJ; Janzen CJ; van Leeuwen F
    J Cell Sci; 2010 Dec; 123(Pt 23):4019-23. PubMed ID: 21084562
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: identification of a new trans-histone pathway.
    Fingerman IM; Li HC; Briggs SD
    Genes Dev; 2007 Aug; 21(16):2018-29. PubMed ID: 17675446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
    Valencia-Sánchez MI; De Ioannes P; Wang M; Truong DM; Lee R; Armache JP; Boeke JD; Armache KJ
    Science; 2021 Jan; 371(6527):. PubMed ID: 33479126
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79.
    Tatum D; Li S
    J Biol Chem; 2011 May; 286(20):17530-5. PubMed ID: 21460225
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.
    Frederiks F; Tzouros M; Oudgenoeg G; van Welsem T; Fornerod M; Krijgsveld J; van Leeuwen F
    Nat Struct Mol Biol; 2008 Jun; 15(6):550-7. PubMed ID: 18511943
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei.
    Janzen CJ; Hake SB; Lowell JE; Cross GA
    Mol Cell; 2006 Aug; 23(4):497-507. PubMed ID: 16916638
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.
    van Welsem T; Korthout T; Ekkebus R; Morais D; Molenaar TM; van Harten K; Poramba-Liyanage DW; Sun SM; Lenstra TL; Srivas R; Ideker T; Holstege FCP; van Attikum H; El Oualid F; Ovaa H; Stulemeijer IJE; Vlaming H; van Leeuwen F
    Nucleic Acids Res; 2018 Nov; 46(21):11251-11261. PubMed ID: 30203048
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2.
    Mellor J
    Mol Cell; 2009 Sep; 35(6):729-30. PubMed ID: 19782019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Progressive methylation of ageing histones by Dot1 functions as a timer.
    De Vos D; Frederiks F; Terweij M; van Welsem T; Verzijlbergen KF; Iachina E; de Graaf EL; Altelaar AF; Oudgenoeg G; Heck AJ; Krijgsveld J; Bakker BM; van Leeuwen F
    EMBO Rep; 2011 Sep; 12(9):956-62. PubMed ID: 21760613
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.
    Wysocki R; Javaheri A; Allard S; Sha F; Côté J; Kron SJ
    Mol Cell Biol; 2005 Oct; 25(19):8430-43. PubMed ID: 16166626
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei.
    Gassen A; Brechtefeld D; Schandry N; Arteaga-Salas JM; Israel L; Imhof A; Janzen CJ
    Nucleic Acids Res; 2012 Nov; 40(20):10302-11. PubMed ID: 22941659
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation.
    Schulze JM; Jackson J; Nakanishi S; Gardner JM; Hentrich T; Haug J; Johnston M; Jaspersen SL; Kobor MS; Shilatifard A
    Mol Cell; 2009 Sep; 35(5):626-41. PubMed ID: 19682934
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dot1 and histone H3K79 methylation in natural telomeric and HM silencing.
    Takahashi YH; Schulze JM; Jackson J; Hentrich T; Seidel C; Jaspersen SL; Kobor MS; Shilatifard A
    Mol Cell; 2011 Apr; 42(1):118-26. PubMed ID: 21474073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes.
    Dindar G; Anger AM; Mehlhorn C; Hake SB; Janzen CJ
    Nat Commun; 2014 Nov; 5():5313. PubMed ID: 25387577
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1.
    Nakanishi S; Lee JS; Gardner KE; Gardner JM; Takahashi YH; Chandrasekharan MB; Sun ZW; Osley MA; Strahl BD; Jaspersen SL; Shilatifard A
    J Cell Biol; 2009 Aug; 186(3):371-7. PubMed ID: 19667127
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor.
    Ontoso D; Acosta I; van Leeuwen F; Freire R; San-Segundo PA
    PLoS Genet; 2013; 9(1):e1003262. PubMed ID: 23382701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.
    Frederiks F; Heynen GJ; van Deventer SJ; Janssen H; van Leeuwen F
    Nucleic Acids Res; 2009 Nov; 37(21):7047-58. PubMed ID: 19778927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [DOT1: a distinct class of histone lysine methyltransferase].
    Gao WL; Liu HL
    Yi Chuan; 2007 Dec; 29(12):1449-54. PubMed ID: 18065378
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
    Mohan M; Herz HM; Takahashi YH; Lin C; Lai KC; Zhang Y; Washburn MP; Florens L; Shilatifard A
    Genes Dev; 2010 Mar; 24(6):574-89. PubMed ID: 20203130
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.