These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 25970773)

  • 1. Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration.
    Zaytseva YY; Harris JW; Mitov MI; Kim JT; Butterfield DA; Lee EY; Weiss HL; Gao T; Evers BM
    Oncotarget; 2015 Aug; 6(22):18891-904. PubMed ID: 25970773
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.
    Ventura R; Mordec K; Waszczuk J; Wang Z; Lai J; Fridlib M; Buckley D; Kemble G; Heuer TS
    EBioMedicine; 2015 Aug; 2(8):808-24. PubMed ID: 26425687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer.
    Drury J; Young LEA; Scott TL; Kelson CO; He D; Liu J; Wu Y; Wang C; Weiss HL; Fan T; Gentry MS; Sun R; Zaytseva YY
    Int J Mol Sci; 2022 Jun; 23(12):. PubMed ID: 35742953
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.
    Zaytseva YY; Elliott VA; Rychahou P; Mustain WC; Kim JT; Valentino J; Gao T; O'Connor KL; Neltner JM; Lee EY; Weiss HL; Evers BM
    Carcinogenesis; 2014 Jun; 35(6):1341-51. PubMed ID: 24510238
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fatty acid synthase regulates invasion and metastasis of colorectal cancer via Wnt signaling pathway.
    Wang H; Xi Q; Wu G
    Cancer Med; 2016 Jul; 5(7):1599-606. PubMed ID: 27139420
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.
    Uddin S; Hussain AR; Ahmed M; Abubaker J; Al-Sanea N; Abduljabbar A; Ashari LH; Alhomoud S; Al-Dayel F; Bavi P; Al-Kuraya KS
    Am J Gastroenterol; 2009 Jul; 104(7):1790-801. PubMed ID: 19491830
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Upregulation of Fatty Acid Synthase Increases Activity of β-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells.
    Kelson CO; Tessmann JW; Geisen ME; He D; Wang C; Gao T; Evers BM; Zaytseva YY
    Cells; 2024 Oct; 13(19):. PubMed ID: 39404424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation.
    Yun SH; Shin SW; Park JI
    Oncol Rep; 2017 Dec; 38(6):3497-3506. PubMed ID: 29130104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AZGP1 suppresses the process of colorectal cancer after upregulating FASN expression via mTOR signal pathway.
    Yu W; Ling J; Yu H; Du J; Liu T
    Gen Physiol Biophys; 2020 May; 39(3):239-248. PubMed ID: 32525817
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth.
    Drury J; Geisen ME; Tessmann JW; Rychahou PG; Kelson CO; He D; Wang C; Evers BM; Zaytseva YY
    Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38732103
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts.
    Santolla MF; Lappano R; De Marco P; Pupo M; Vivacqua A; Sisci D; Abonante S; Iacopetta D; Cappello AR; Dolce V; Maggiolini M
    J Biol Chem; 2012 Dec; 287(52):43234-45. PubMed ID: 23135268
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Speckle-type POZ protein suppresses lipid accumulation and prostate cancer growth by stabilizing fatty acid synthase.
    Gang X; Xuan L; Zhao X; Lv Y; Li F; Wang Y; Wang G
    Prostate; 2019 Jun; 79(8):864-871. PubMed ID: 30955223
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Global gene deregulations in FASN silenced retinoblastoma cancer cells: molecular and clinico-pathological correlations.
    Sangeetha M; Deepa PR; Rishi P; Khetan V; Krishnakumar S
    J Cell Biochem; 2015 Nov; 116(11):2676-94. PubMed ID: 25958981
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
    Zaytseva YY; Rychahou PG; Gulhati P; Elliott VA; Mustain WC; O'Connor K; Morris AJ; Sunkara M; Weiss HL; Lee EY; Evers BM
    Cancer Res; 2012 Mar; 72(6):1504-17. PubMed ID: 22266115
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FABP5 suppresses colorectal cancer progression via mTOR-mediated autophagy by decreasing FASN expression.
    Ye M; Hu C; Chen T; Yu P; Chen J; Lu F; Xu L; Zhong Y; Yan L; Kan J; Bai J; Li X; Tian Y; Tang Q
    Int J Biol Sci; 2023; 19(10):3115-3127. PubMed ID: 37416772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Progress in the development of fatty acid synthase inhibitors as anticancer targets.
    Mullen GE; Yet L
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4363-9. PubMed ID: 26364942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.
    Zaytseva YY; Rychahou PG; Le AT; Scott TL; Flight RM; Kim JT; Harris J; Liu J; Wang C; Morris AJ; Sivakumaran TA; Fan T; Moseley H; Gao T; Lee EY; Weiss HL; Heuer TS; Kemble G; Evers M
    Oncotarget; 2018 May; 9(37):24787-24800. PubMed ID: 29872506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fatty acid synthase regulates proliferation and migration of colorectal cancer cells via HER2-PI3K/Akt signaling pathway.
    Li N; Bu X; Tian X; Wu P; Yang L; Huang P
    Nutr Cancer; 2012 Aug; 64(6):864-70. PubMed ID: 22860766
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Positive feedback regulation between Akt phosphorylation and fatty acid synthase expression in osteosarcoma.
    Wang H; Luo QF; Peng AF; Long XH; Wang TF; Liu ZL; Zhang GM; Zhou RP; Gao S; Zhou Y; Chen WZ
    Int J Mol Med; 2014 Mar; 33(3):633-9. PubMed ID: 24366211
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity.
    Hopperton KE; Duncan RE; Bazinet RP; Archer MC
    Exp Cell Res; 2014 Jan; 320(2):302-10. PubMed ID: 24200503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.