BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 25971952)

  • 1. Phosphodiesterase 8B and cyclic AMP signaling in the adrenal cortex.
    Leal LF; Szarek E; Faucz F; Stratakis CA
    Endocrine; 2015 Sep; 50(1):27-31. PubMed ID: 25971952
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland.
    Tsai LC; Shimizu-Albergine M; Beavo JA
    Mol Pharmacol; 2011 Apr; 79(4):639-48. PubMed ID: 21187369
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex.
    Horvath A; Giatzakis C; Tsang K; Greene E; Osorio P; Boikos S; Libè R; Patronas Y; Robinson-White A; Remmers E; Bertherat J; Nesterova M; Stratakis CA
    Eur J Hum Genet; 2008 Oct; 16(10):1245-53. PubMed ID: 18431404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes.
    Bimpaki EI; Nesterova M; Stratakis CA
    Eur J Endocrinol; 2009 Jul; 161(1):153-61. PubMed ID: 19429701
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations.
    Almeida MQ; Azevedo MF; Xekouki P; Bimpaki EI; Horvath A; Collins MT; Karaviti LP; Jeha GS; Bhattacharyya N; Cheadle C; Watkins T; Bourdeau I; Nesterova M; Stratakis CA
    J Clin Endocrinol Metab; 2012 Apr; 97(4):E687-93. PubMed ID: 22259056
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphodiesterase 11A expression in the adrenal cortex, primary pigmented nodular adrenocortical disease, and other corticotropin-independent lesions.
    Boikos SA; Horvath A; Heyerdahl S; Stein E; Robinson-White A; Bossis I; Bertherat J; Carney JA; Stratakis CA
    Horm Metab Res; 2008 May; 40(5):347-53. PubMed ID: 18491255
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Active site coupling in PDE:PKA complexes promotes resetting of mammalian cAMP signaling.
    Krishnamurthy S; Moorthy BS; Xin Xiang L; Xin Shan L; Bharatham K; Tulsian NK; Mihalek I; Anand GS
    Biophys J; 2014 Sep; 107(6):1426-40. PubMed ID: 25229150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Signaling at crossroads: the dialogue between PDEs and PKA is spoken in multiple languages.
    Moleschi K; Melacini G
    Biophys J; 2014 Sep; 107(6):1259-60. PubMed ID: 25229132
    [No Abstract]   [Full Text] [Related]  

  • 9. cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse.
    Stratakis CA
    Mol Cell Endocrinol; 2013 May; 371(1-2):208-20. PubMed ID: 23485729
    [TBL] [Abstract][Full Text] [Related]  

  • 10. How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?
    Almeida MQ; Stratakis CA
    Mol Cell Endocrinol; 2011 Apr; 336(1-2):162-8. PubMed ID: 21111774
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The transcriptome that mediates increased cyclic adenosine monophosphate signaling in PRKAR1A defects and other settings.
    Azevedo MF; Stratakis CA
    Endocr Pract; 2011; 17 Suppl 3(0 3):2-7. PubMed ID: 21454229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours.
    Rothenbuhler A; Horvath A; Libé R; Faucz FR; Fratticci A; Raffin Sanson ML; Vezzosi D; Azevedo M; Levy I; Almeida MQ; Lodish M; Nesterova M; Bertherat J; Stratakis CA
    Clin Endocrinol (Oxf); 2012 Aug; 77(2):195-9. PubMed ID: 22335482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Dunce cAMP phosphodiesterase PDE-4 negatively regulates G alpha(s)-dependent and G alpha(s)-independent cAMP pools in the Caenorhabditis elegans synaptic signaling network.
    Charlie NK; Thomure AM; Schade MA; Miller KG
    Genetics; 2006 May; 173(1):111-30. PubMed ID: 16624912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.
    Calebiro D; Hannawacker A; Lyga S; Bathon K; Zabel U; Ronchi C; Beuschlein F; Reincke M; Lorenz K; Allolio B; Kisker C; Fassnacht M; Lohse MJ
    Nat Commun; 2014 Dec; 5():5680. PubMed ID: 25477193
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.
    Robinson-White A; Meoli E; Stergiopoulos S; Horvath A; Boikos S; Bossis I; Stratakis CA
    J Clin Endocrinol Metab; 2006 Jun; 91(6):2380-8. PubMed ID: 16569736
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PRKAR1A mutations in primary pigmented nodular adrenocortical disease.
    Cazabat L; Ragazzon B; Groussin L; Bertherat J
    Pituitary; 2006; 9(3):211-9. PubMed ID: 17036196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.
    Conti M; Richter W; Mehats C; Livera G; Park JY; Jin C
    J Biol Chem; 2003 Feb; 278(8):5493-6. PubMed ID: 12493749
    [No Abstract]   [Full Text] [Related]  

  • 18. Transcriptional activation of phosphodiesterase 7B1 by dopamine D1 receptor stimulation through the cyclic AMP/cyclic AMP-dependent protein kinase/cyclic AMP-response element binding protein pathway in primary striatal neurons.
    Sasaki T; Kotera J; Omori K
    J Neurochem; 2004 Apr; 89(2):474-83. PubMed ID: 15056290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation.
    Lu JY; Sewer MB
    Mol Cell Biol; 2015 Apr; 35(7):1223-37. PubMed ID: 25605330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation.
    Leal LF; Szarek E; Berthon A; Nesterova M; Faucz FR; London E; Mercier C; Abu-Asab M; Starost MF; Dye L; Bilinska B; Kotula-Balak M; Antonini SR; Stratakis CA
    Mol Cell Endocrinol; 2021 Feb; 522():111117. PubMed ID: 33338547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.