BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 25977332)

  • 1. Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus without Compromising Anticancer Activity.
    Browne A; Tookman LA; Ingemarsdotter CK; Bouwman RD; Pirlo K; Wang Y; McNeish IA; Lockley M
    Cancer Res; 2015 Jul; 75(14):2811-21. PubMed ID: 25977332
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the inflammatory cytokine TNF-α increases adenovirus activity in ovarian cancer via modulation of cIAP1/2 expression.
    Salako MA; Kulbe H; Ingemarsdotter CK; Pirlo KJ; Williams SL; Lockley M; Balkwill FR; McNeish IA
    Mol Ther; 2011 Mar; 19(3):490-9. PubMed ID: 21081903
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Carvedilol targets β-arrestins to rewire innate immunity and improve oncolytic adenoviral therapy.
    Hoare JI; Osmani B; O'Sullivan EA; Browne A; Campbell N; Metcalf S; Nicolini F; Saxena J; Martin SA; Lockley M
    Commun Biol; 2022 Feb; 5(1):106. PubMed ID: 35115660
    [TBL] [Abstract][Full Text] [Related]  

  • 4. E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers.
    Wakayama M; Abei M; Kawashima R; Seo E; Fukuda K; Ugai H; Murata T; Tanaka N; Hyodo I; Hamada H; Yokoyama KK
    Clin Cancer Res; 2007 May; 13(10):3043-50. PubMed ID: 17505007
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control.
    Ingemarsdotter CK; Tookman LA; Browne A; Pirlo K; Cutts R; Chelela C; Khurrum KF; Leung EY; Dowson S; Webber L; Khan I; Ennis D; Syed N; Crook TR; Brenton JD; Lockley M; McNeish IA
    Mol Oncol; 2015 Apr; 9(4):791-805. PubMed ID: 25560085
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.
    Bhattacharyya M; Francis J; Eddouadi A; Lemoine NR; Halldén G
    Cancer Gene Ther; 2011 Oct; 18(10):734-43. PubMed ID: 21836633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bevacizumab increases viral distribution in human anaplastic thyroid carcinoma xenografts and enhances the effects of E1A-defective adenovirus dl922-947.
    Libertini S; Iacuzzo I; Perruolo G; Scala S; Ieranò C; Franco R; Hallden G; Portella G
    Clin Cancer Res; 2008 Oct; 14(20):6505-14. PubMed ID: 18927290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts.
    Radhakrishnan S; Miranda E; Ekblad M; Holford A; Pizarro MT; Lemoine NR; Halldén G
    Hum Gene Ther; 2010 Oct; 21(10):1311-25. PubMed ID: 20497039
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma.
    Passaro C; Borriello F; Vastolo V; Di Somma S; Scamardella E; Gigantino V; Franco R; Marone G; Portella G
    Oncotarget; 2016 Jan; 7(2):1500-15. PubMed ID: 26625205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents.
    González-Pastor R; Ashshi AM; El-Shemi AG; Dmitriev IP; Kashentseva EA; Lu ZH; Goedegebuure SP; Podhajcer OL; Curiel DT
    J Ovarian Res; 2019 Feb; 12(1):18. PubMed ID: 30767772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer.
    Ingemarsdotter CK; Baird SK; Connell CM; Öberg D; Halldén G; McNeish IA
    Oncogene; 2010 Nov; 29(45):6051-63. PubMed ID: 20729921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cloning of carrier cells infected with oncolytic adenovirus driven by midkine promoter and biosafety studies.
    Hamada K; Takagi S; Kuboshima H; Shimada H; Takagi K; Yasuoka T; Matsubara K; Sassa Y; Furuya T; Suzuki K; Uchide T; Mizutani T; Tani K; Itoh H; Sugiyama T
    J Gene Med; 2019 Feb; 21(2-3):e3064. PubMed ID: 30548997
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel CRAd in combination with cisplatin enhanced the antitumor efficacy in ovarian cancer.
    Zhang B; Liu Y; Zhang P; Wei Y; Yin X; Zheng J
    Int J Gynecol Cancer; 2011 Dec; 21(9):1540-6. PubMed ID: 22080895
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macrophage beta3 integrin suppresses hyperlipidemia-induced inflammation by modulating TNFalpha expression.
    Schneider JG; Zhu Y; Coleman T; Semenkovich CF
    Arterioscler Thromb Vasc Biol; 2007 Dec; 27(12):2699-706. PubMed ID: 17951320
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin.
    Lockley M; Fernandez M; Wang Y; Li NF; Conroy S; Lemoine N; McNeish I
    Cancer Res; 2006 Jan; 66(2):989-98. PubMed ID: 16424034
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combination of a MDR1-targeted replicative adenovirus and chemotherapy for the therapy of pretreated ovarian cancer.
    Rein DT; Volkmer A; Bauerschmitz G; Beyer IM; Janni W; Fleisch MC; Welter AK; Bauerschlag D; Schöndorf T; Breidenbach M
    J Cancer Res Clin Oncol; 2012 Apr; 138(4):603-10. PubMed ID: 22209976
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination.
    Takakura M; Nakamura M; Kyo S; Hashimoto M; Mori N; Ikoma T; Mizumoto Y; Fujiwara T; Urata Y; Inoue M
    Cancer Gene Ther; 2010 Jan; 17(1):11-9. PubMed ID: 19662088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In Vitro and In Vivo Efficacy of a Stroma-Targeted, Tumor Microenvironment Responsive Oncolytic Adenovirus in Different Preclinical Models of Cancer.
    Alfano A; Cafferata EGA; Gangemi M; Nicola Candia A; Malnero CM; Bermudez I; Lopez MV; Ríos GD; Rotondaro C; Cuneo N; Curiel DT; Podhajcer OL; Lopez MV
    Int J Mol Sci; 2023 Jun; 24(12):. PubMed ID: 37373140
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells.
    Libertini S; Iacuzzo I; Ferraro A; Vitale M; Bifulco M; Fusco A; Portella G
    Endocrinology; 2007 Nov; 148(11):5186-94. PubMed ID: 17690162
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo.
    Botta G; Passaro C; Libertini S; Abagnale A; Barbato S; Maione AS; Hallden G; Beguinot F; Formisano P; Portella G
    Hum Gene Ther; 2012 Jun; 23(6):623-34. PubMed ID: 22475378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.