BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

590 related articles for article (PubMed ID: 25977370)

  • 1. Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
    Bell RJ; Rube HT; Kreig A; Mancini A; Fouse SD; Nagarajan RP; Choi S; Hong C; He D; Pekmezci M; Wiencke JK; Wrensch MR; Chang SM; Walsh KM; Myong S; Song JS; Costello JF
    Science; 2015 May; 348(6238):1036-9. PubMed ID: 25977370
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations.
    Makowski MM; Willems E; Fang J; Choi J; Zhang T; Jansen PW; Brown KM; Vermeulen M
    Proteomics; 2016 Feb; 16(3):417-26. PubMed ID: 26553150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.
    Mancini A; Xavier-Magalhães A; Woods WS; Nguyen KT; Amen AM; Hayes JL; Fellmann C; Gapinske M; McKinney AM; Hong C; Jones LE; Walsh KM; Bell RJA; Doudna JA; Costa BM; Song JS; Perez-Pinera P; Costello JF
    Cancer Cell; 2018 Sep; 34(3):513-528.e8. PubMed ID: 30205050
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer-specific loss of
    Amen AM; Fellmann C; Soczek KM; Ren SM; Lew RJ; Knott GJ; Park JE; McKinney AM; Mancini A; Doudna JA; Costello JF
    Proc Natl Acad Sci U S A; 2021 Mar; 118(13):. PubMed ID: 33758097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer.
    McKinney AM; Mathur R; Stevers NO; Molinaro AM; Chang SM; Phillips JJ; Costello JF
    Cell Rep; 2022 Sep; 40(12):111344. PubMed ID: 36130485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends.
    Yuan X; Dai M; Xu D
    Cancer Lett; 2020 Nov; 493():1-9. PubMed ID: 32768523
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions.
    Min J; Shay JW
    Cancer Discov; 2016 Nov; 6(11):1212-1214. PubMed ID: 27807101
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.
    McKelvey BA; Gilpatrick T; Wang Y; Timp W; Umbricht CB; Zeiger MA
    Thyroid; 2020 Oct; 30(10):1470-1481. PubMed ID: 32228178
    [No Abstract]   [Full Text] [Related]  

  • 9. Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
    Stern JL; Theodorescu D; Vogelstein B; Papadopoulos N; Cech TR
    Genes Dev; 2015 Nov; 29(21):2219-24. PubMed ID: 26515115
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.
    Barger CJ; Suwala AK; Soczek KM; Wang AS; Kim MY; Hong C; Doudna JA; Chang SM; Phillips JJ; Solomon DA; Costello JF
    Nat Commun; 2022 Sep; 13(1):5430. PubMed ID: 36114166
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of human telomerase reverse transcriptase promoter methylation and transcription factor binding in differentiated thyroid cancer cell lines.
    Avin BA; Wang Y; Gilpatrick T; Workman RE; Lee I; Timp W; Umbricht CB; Zeiger MA
    Genes Chromosomes Cancer; 2019 Aug; 58(8):530-540. PubMed ID: 30664813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic targeting of FOS in mutant
    Liu R; Tan J; Shen X; Jiang K; Wang C; Zhu G; Xing M
    Proc Natl Acad Sci U S A; 2021 Mar; 118(11):. PubMed ID: 33836600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region.
    Li CL; Li CY; Lin YY; Ho MC; Chen DS; Chen PJ; Yeh SH
    Hepatology; 2019 Feb; 69(2):498-512. PubMed ID: 30070724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression.
    Yuan X; Mu N; Wang N; Strååt K; Sofiadis A; Guo Y; Stenman A; Li K; Cheng G; Zhang L; Kong F; Ekblad L; Wennerberg J; Nilsson IL; Juhlin CC; Larsson C; Xu D
    Oncogene; 2019 Feb; 38(7):965-979. PubMed ID: 30181547
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer.
    Liu R; Zhang T; Zhu G; Xing M
    Nat Commun; 2018 Feb; 9(1):579. PubMed ID: 29422527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.
    Li Y; Zhou QL; Sun W; Chandrasekharan P; Cheng HS; Ying Z; Lakshmanan M; Raju A; Tenen DG; Cheng SY; Chuang KH; Li J; Prabhakar S; Li M; Tergaonkar V
    Nat Cell Biol; 2015 Oct; 17(10):1327-38. PubMed ID: 26389665
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TERT promoter alterations could provide a solution for Peto's paradox in rodents.
    Vedelek B; Maddali AK; Davenova N; Vedelek V; Boros IM
    Sci Rep; 2020 Nov; 10(1):20815. PubMed ID: 33257697
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
    Akıncılar SC; Khattar E; Boon PL; Unal B; Fullwood MJ; Tergaonkar V
    Cancer Discov; 2016 Nov; 6(11):1276-1291. PubMed ID: 27650951
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1.
    Xu X; Li Y; Bharath SR; Ozturk MB; Bowler MW; Loo BZL; Tergaonkar V; Song H
    Nat Commun; 2018 Aug; 9(1):3183. PubMed ID: 30093619
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Brain regions associated with telomerase reverse transcriptase promoter mutations in primary glioblastomas.
    Fan X; Wang Y; Liu Y; Liu X; Zhang C; Wang L; Li S; Ma J; Jiang T
    J Neurooncol; 2016 Jul; 128(3):455-62. PubMed ID: 27230769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.