185 related articles for article (PubMed ID: 25977998)
1. Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduction: Implications for in Vitro Models and Toxicogenomics.
Luczak MW; Green SE; Zhitkovich A
Environ Health Perspect; 2016 Jan; 124(1):61-6. PubMed ID: 25977998
[TBL] [Abstract][Full Text] [Related]
2. Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest.
Ha L; Ceryak S; Patierno SR
J Biol Chem; 2003 May; 278(20):17885-94. PubMed ID: 12637545
[TBL] [Abstract][Full Text] [Related]
3. Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels.
Reynolds M; Armknecht S; Johnston T; Zhitkovich A
Mutagenesis; 2012 Jul; 27(4):437-43. PubMed ID: 22241526
[TBL] [Abstract][Full Text] [Related]
4. Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process.
Wong V; Armknecht S; Zhitkovich A
J Trace Elem Med Biol; 2012 Jun; 26(2-3):192-6. PubMed ID: 22572042
[TBL] [Abstract][Full Text] [Related]
5. DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination.
DeLoughery Z; Luczak MW; Ortega-Atienza S; Zhitkovich A
Toxicol Sci; 2015 Jan; 143(1):54-63. PubMed ID: 25288669
[TBL] [Abstract][Full Text] [Related]
6. Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not p53.
Reynolds M; Zhitkovich A
Carcinogenesis; 2007 Jul; 28(7):1613-20. PubMed ID: 17301063
[TBL] [Abstract][Full Text] [Related]
7. Carcinogenic chromium(VI) induces cross-linking of vitamin C to DNA in vitro and in human lung A549 cells.
Quievryn G; Messer J; Zhitkovich A
Biochemistry; 2002 Mar; 41(9):3156-67. PubMed ID: 11863455
[TBL] [Abstract][Full Text] [Related]
8. ATR activation by Cr-DNA damage is a major survival response establishing late S and G2 checkpoints after Cr(VI) exposure.
Valiente S; Krawic C; Zhitkovich A
Toxicol Appl Pharmacol; 2023 Oct; 477():116696. PubMed ID: 37734571
[TBL] [Abstract][Full Text] [Related]
9. ATR regulates hexavalent chromium-induced S-phase checkpoint through phosphorylation of SMC1.
Wakeman TP; Xu B
Mutat Res; 2006 Nov; 610(1-2):14-20. PubMed ID: 16876463
[TBL] [Abstract][Full Text] [Related]
10. In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI).
Yuann JM; Liu KJ; Hamilton JW; Wetterhahn KE
Carcinogenesis; 1999 Jul; 20(7):1267-75. PubMed ID: 10383900
[TBL] [Abstract][Full Text] [Related]
11. Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms.
O'Brien TJ; Ceryak S; Patierno SR
Mutat Res; 2003 Dec; 533(1-2):3-36. PubMed ID: 14643411
[TBL] [Abstract][Full Text] [Related]
12. p53 Activation by Cr(VI): A Transcriptionally Limited Response Induced by ATR Kinase in S-Phase.
Luczak MW; Krawic C; Zhitkovich A
Toxicol Sci; 2019 Nov; 172(1):11-22. PubMed ID: 31388677
[TBL] [Abstract][Full Text] [Related]
13. Apoptosis and P53 induction in human lung fibroblasts exposed to chromium (VI): effect of ascorbate and tocopherol.
Carlisle DL; Pritchard DE; Singh J; Owens BM; Blankenship LJ; Orenstein JM; Patierno SR
Toxicol Sci; 2000 May; 55(1):60-8. PubMed ID: 10788560
[TBL] [Abstract][Full Text] [Related]
14. Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair.
Reynolds M; Stoddard L; Bespalov I; Zhitkovich A
Nucleic Acids Res; 2007; 35(2):465-76. PubMed ID: 17169990
[TBL] [Abstract][Full Text] [Related]
15. Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX.
Ha L; Ceryak S; Patierno SR
Carcinogenesis; 2004 Nov; 25(11):2265-74. PubMed ID: 15284180
[TBL] [Abstract][Full Text] [Related]
16. Chromium(VI) causes interstrand DNA cross-linking in vitro but shows no hypersensitivity in cross-link repair-deficient human cells.
Morse JL; Luczak MW; Zhitkovich A
Chem Res Toxicol; 2013 Oct; 26(10):1591-8. PubMed ID: 24059640
[TBL] [Abstract][Full Text] [Related]
17. Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: lack of effect of ERK.
Ceryak S; Zingariello C; O'Brien T; Patierno SR
Mol Cell Biochem; 2004 Jan; 255(1-2):139-49. PubMed ID: 14971655
[TBL] [Abstract][Full Text] [Related]
18. Genotoxicity and mutagenicity of chromium(VI)/ascorbate-generated DNA adducts in human and bacterial cells.
Quievryn G; Peterson E; Messer J; Zhitkovich A
Biochemistry; 2003 Feb; 42(4):1062-70. PubMed ID: 12549927
[TBL] [Abstract][Full Text] [Related]
19. Chemical mechanisms of DNA damage by carcinogenic chromium(VI).
Krawic C; Zhitkovich A
Adv Pharmacol; 2023; 96():25-46. PubMed ID: 36858775
[TBL] [Abstract][Full Text] [Related]
20. The intracellular redox stress caused by hexavalent chromium is selective for proteins that have key roles in cell survival and thiol redox control.
Myers JM; Antholine WE; Myers CR
Toxicology; 2011 Mar; 281(1-3):37-47. PubMed ID: 21237240
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
