These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 25979092)

  • 1. The acetyl-CoA carboxylase enzyme: a target for cancer therapy?
    Wang C; Ma J; Zhang N; Yang Q; Jin Y; Wang Y
    Expert Rev Anticancer Ther; 2015 Jun; 15(6):667-76. PubMed ID: 25979092
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.
    Beckers A; Organe S; Timmermans L; Scheys K; Peeters A; Brusselmans K; Verhoeven G; Swinnen JV
    Cancer Res; 2007 Sep; 67(17):8180-7. PubMed ID: 17804731
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acetyl-CoA carboxylase (ACC) as a therapeutic target for metabolic syndrome and recent developments in ACC1/2 inhibitors.
    Chen L; Duan Y; Wei H; Ning H; Bi C; Zhao Y; Qin Y; Li Y
    Expert Opin Investig Drugs; 2019 Oct; 28(10):917-930. PubMed ID: 31430206
    [No Abstract]   [Full Text] [Related]  

  • 4. Acetyl CoA carboxylase shares control of fatty acid synthesis with fatty acid synthase in bovine mammary homogenate.
    Wright TC; Cant JP; Brenna JT; McBride BW
    J Dairy Sci; 2006 Jul; 89(7):2552-8. PubMed ID: 16772574
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.
    Brusselmans K; De Schrijver E; Verhoeven G; Swinnen JV
    Cancer Res; 2005 Aug; 65(15):6719-25. PubMed ID: 16061653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
    Svensson RU; Parker SJ; Eichner LJ; Kolar MJ; Wallace M; Brun SN; Lombardo PS; Van Nostrand JL; Hutchins A; Vera L; Gerken L; Greenwood J; Bhat S; Harriman G; Westlin WF; Harwood HJ; Saghatelian A; Kapeller R; Metallo CM; Shaw RJ
    Nat Med; 2016 Oct; 22(10):1108-1119. PubMed ID: 27643638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemical genetics of acetyl-CoA carboxylases.
    Zu X; Zhong J; Luo D; Tan J; Zhang Q; Wu Y; Liu J; Cao R; Wen G; Cao D
    Molecules; 2013 Jan; 18(2):1704-19. PubMed ID: 23358327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
    Thupari JN; Pinn ML; Kuhajda FP
    Biochem Biophys Res Commun; 2001 Jul; 285(2):217-23. PubMed ID: 11444828
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recent development in acetyl-CoA carboxylase inhibitors and their potential as novel drugs.
    Wu X; Huang T
    Future Med Chem; 2020 Mar; 12(6):533-561. PubMed ID: 32048880
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of Acetyl-CoA Carboxylases in the Basal Dinoflagellate Amphidinium carterae.
    Haq S; Bachvaroff TR; Place AR
    Mar Drugs; 2017 May; 15(6):. PubMed ID: 28587129
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acetyl-CoA carboxylase-a as a novel target for cancer therapy.
    Wang C; Rajput S; Watabe K; Liao DF; Cao D
    Front Biosci (Schol Ed); 2010 Jan; 2(2):515-26. PubMed ID: 20036965
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
    Wang MD; Wu H; Fu GB; Zhang HL; Zhou X; Tang L; Dong LW; Qin CJ; Huang S; Zhao LH; Zeng M; Wu MC; Yan HX; Wang HY
    Hepatology; 2016 Apr; 63(4):1272-86. PubMed ID: 26698170
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The bacterial signal transduction protein GlnB regulates the committed step in fatty acid biosynthesis by acting as a dissociable regulatory subunit of acetyl-CoA carboxylase.
    Gerhardt EC; Rodrigues TE; Müller-Santos M; Pedrosa FO; Souza EM; Forchhammer K; Huergo LF
    Mol Microbiol; 2015 Mar; 95(6):1025-35. PubMed ID: 25557370
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and in vitro evaluation of novel spiroketopyrazoles as acetyl-CoA carboxylase inhibitors and potential antitumor agents.
    Huang T; Wu X; Yan S; Liu T; Yin X
    Eur J Med Chem; 2021 Feb; 212():113036. PubMed ID: 33276990
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Acetyl-CoA carboxylase in Reuber hepatoma cells: variation in enzyme activity, insulin regulation, and cellular lipid content.
    Bianchi A; Evans JL; Nordlund AC; Watts TD; Witters LA
    J Cell Biochem; 1992 Jan; 48(1):86-97. PubMed ID: 1349893
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
    Lee CK; Cheong HK; Ryu KS; Lee JI; Lee W; Jeon YH; Cheong C
    Proteins; 2008 Aug; 72(2):613-24. PubMed ID: 18247344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure, function and selective inhibition of bacterial acetyl-coa carboxylase.
    Polyak SW; Abell AD; Wilce MC; Zhang L; Booker GW
    Appl Microbiol Biotechnol; 2012 Feb; 93(3):983-92. PubMed ID: 22183085
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roles of acetyl-CoA carboxylase beta in muscle cell differentiation and in mitochondrial fatty acid oxidation.
    Lee JK; Kim KH
    Biochem Biophys Res Commun; 1999 Jan; 254(3):657-60. PubMed ID: 9920796
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting acetyl-CoA carboxylases: small molecular inhibitors and their therapeutic potential.
    Luo DX; Tong DJ; Rajput S; Wang C; Liao DF; Cao D; Maser E
    Recent Pat Anticancer Drug Discov; 2012 May; 7(2):168-84. PubMed ID: 22339356
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth.
    Petrova E; Scholz A; Paul J; Sturz A; Haike K; Siegel F; Mumberg D; Liu N
    Oncotarget; 2017 Jul; 8(30):48660-48670. PubMed ID: 27750213
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.