These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 25981125)

  • 21. Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease.
    Morawski M; Hartlage-Rübsamen M; Jäger C; Waniek A; Schilling S; Schwab C; McGeer PL; Arendt T; Demuth HU; Rossner S
    Acta Neuropathol; 2010 Aug; 120(2):195-207. PubMed ID: 20383514
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Glutaminyl Cyclase, Diseases, and Development of Glutaminyl Cyclase Inhibitors.
    Xu C; Wang YN; Wu H
    J Med Chem; 2021 May; 64(10):6549-6565. PubMed ID: 34000808
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The Bacteroidetes Q-rule and glutaminyl cyclase activity increase the stability of extracytoplasmic proteins.
    Szczęśniak K; Veillard F; Scavenius C; Chudzik K; Ferenc K; Bochtler M; Potempa J; Mizgalska D
    mBio; 2023 Oct; 14(5):e0098023. PubMed ID: 37750700
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.
    Jawhar S; Wirths O; Schilling S; Graubner S; Demuth HU; Bayer TA
    J Biol Chem; 2011 Feb; 286(6):4454-60. PubMed ID: 21148560
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pyroglutamate-amyloid-β and glutaminyl cyclase are colocalized with amyloid-β in secretory vesicles and undergo activity-dependent, regulated secretion.
    Cynis H; Funkelstein L; Toneff T; Mosier C; Ziegler M; Koch B; Demuth HU; Hook V
    Neurodegener Dis; 2014; 14(2):85-97. PubMed ID: 24943989
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides.
    Fischer WH; Spiess J
    Proc Natl Acad Sci U S A; 1987 Jun; 84(11):3628-32. PubMed ID: 3473473
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology.
    Schilling S; Zeitschel U; Hoffmann T; Heiser U; Francke M; Kehlen A; Holzer M; Hutter-Paier B; Prokesch M; Windisch M; Jagla W; Schlenzig D; Lindner C; Rudolph T; Reuter G; Cynis H; Montag D; Demuth HU; Rossner S
    Nat Med; 2008 Oct; 14(10):1106-11. PubMed ID: 18836460
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation.
    Huang KF; Liu YL; Cheng WJ; Ko TP; Wang AH
    Proc Natl Acad Sci U S A; 2005 Sep; 102(37):13117-22. PubMed ID: 16135565
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Molecular characterization of tick salivary gland glutaminyl cyclase.
    Adamson SW; Browning RE; Chao CC; Bateman RC; Ching WM; Karim S
    Insect Biochem Mol Biol; 2013 Sep; 43(9):781-93. PubMed ID: 23770496
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Continuous spectrometric assays for glutaminyl cyclase activity.
    Schilling S; Hoffmann T; Wermann M; Heiser U; Wasternack C; Demuth HU
    Anal Biochem; 2002 Apr; 303(1):49-56. PubMed ID: 11906150
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Crystal structure and functional analysis of the glutaminyl cyclase from Xanthomonas campestris.
    Huang WL; Wang YR; Ko TP; Chia CY; Huang KF; Wang AH
    J Mol Biol; 2010 Aug; 401(3):374-88. PubMed ID: 20558177
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Crystal structure of papaya glutaminyl cyclase, an archetype for plant and bacterial glutaminyl cyclases.
    Wintjens R; Belrhali H; Clantin B; Azarkan M; Bompard C; Baeyens-Volant D; Looze Y; Villeret V
    J Mol Biol; 2006 Mar; 357(2):457-70. PubMed ID: 16438985
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Investigation of N-terminal glutamate cyclization of recombinant monoclonal antibody in formulation development.
    Yu L; Vizel A; Huff MB; Young M; Remmele RL; He B
    J Pharm Biomed Anal; 2006 Oct; 42(4):455-63. PubMed ID: 16828250
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution.
    Schilling S; Wasternack C; Demuth HU
    Biol Chem; 2008 Aug; 389(8):983-91. PubMed ID: 18979624
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC.
    Höfling C; Indrischek H; Höpcke T; Waniek A; Cynis H; Koch B; Schilling S; Morawski M; Demuth HU; Roßner S; Hartlage-Rübsamen M
    Int J Dev Neurosci; 2014 Aug; 36():64-73. PubMed ID: 24886834
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Human glutaminyl cyclase: Structure, function, inhibitors and involvement in Alzheimer's disease.
    Vijayan DK; Zhang KYJ
    Pharmacol Res; 2019 Sep; 147():104342. PubMed ID: 31288079
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Glutaminyl cyclase activity is a characteristic feature of human cerebrospinal fluid.
    Gontsarova A; Kaufmann E; Tumani H; Dressel A; Mandel F; Wiesmüller KH; Kunert-Keil C; Brinkmeier H
    Clin Chim Acta; 2008 Mar; 389(1-2):152-9. PubMed ID: 18187042
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.
    Ruiz-Carrillo D; Koch B; Parthier C; Wermann M; Dambe T; Buchholz M; Ludwig HH; Heiser U; Rahfeld JU; Stubbs MT; Schilling S; Demuth HU
    Biochemistry; 2011 Jul; 50(28):6280-8. PubMed ID: 21671571
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding.
    Huang KF; Hsu HL; Karim S; Wang AH
    Acta Crystallogr D Biol Crystallogr; 2014 Mar; 70(Pt 3):789-801. PubMed ID: 24598748
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics.
    Stephan A; Wermann M; von Bohlen A; Koch B; Cynis H; Demuth HU; Schilling S
    FEBS J; 2009 Nov; 276(22):6522-36. PubMed ID: 19804409
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.