These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
622 related articles for article (PubMed ID: 25986689)
1. High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs Antagonists. Wu B; Barile E; De SK; Wei J; Purves A; Pellecchia M Curr Top Med Chem; 2015; 15(20):2032-42. PubMed ID: 25986689 [TBL] [Abstract][Full Text] [Related]
2. HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery. Wu B; Zhang Z; Noberini R; Barile E; Giulianotti M; Pinilla C; Houghten RA; Pasquale EB; Pellecchia M Chem Biol; 2013 Jan; 20(1):19-33. PubMed ID: 23352136 [TBL] [Abstract][Full Text] [Related]
3. Counting on Fragment Based Drug Design Approach for Drug Discovery. Kashyap A; Singh PK; Silakari O Curr Top Med Chem; 2018; 18(27):2284-2293. PubMed ID: 30499406 [TBL] [Abstract][Full Text] [Related]
4. Enthalpy-Based Screening of Focused Combinatorial Libraries for the Identification of Potent and Selective Ligands. Baggio C; Udompholkul P; Barile E; Pellecchia M ACS Chem Biol; 2017 Dec; 12(12):2981-2989. PubMed ID: 29094589 [TBL] [Abstract][Full Text] [Related]
5. Mass spectrometry for fragment screening. Chan DS; Whitehouse AJ; Coyne AG; Abell C Essays Biochem; 2017 Nov; 61(5):465-473. PubMed ID: 28986384 [TBL] [Abstract][Full Text] [Related]
6. Fragment-based drug discovery and its application to challenging drug targets. Price AJ; Howard S; Cons BD Essays Biochem; 2017 Nov; 61(5):475-484. PubMed ID: 29118094 [TBL] [Abstract][Full Text] [Related]
7. Combining NMR and X-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors. Wyss DF; Wang YS; Eaton HL; Strickland C; Voigt JH; Zhu Z; Stamford AW Top Curr Chem; 2012; 317():83-114. PubMed ID: 21647837 [TBL] [Abstract][Full Text] [Related]
8. Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening. Mady ASA; Liao C; Bajwa N; Kump KJ; Abulwerdi FA; Lev KL; Miao L; Grigsby SM; Perdih A; Stuckey JA; Du Y; Fu H; Nikolovska-Coleska Z Sci Rep; 2018 Jul; 8(1):10210. PubMed ID: 29976942 [TBL] [Abstract][Full Text] [Related]
9. Biophysical screening for the discovery of small-molecule ligands. Ciulli A Methods Mol Biol; 2013; 1008():357-88. PubMed ID: 23729259 [TBL] [Abstract][Full Text] [Related]
10. Effective progression of nuclear magnetic resonance-detected fragment hits. Eaton HL; Wyss DF Methods Enzymol; 2011; 493():447-68. PubMed ID: 21371601 [TBL] [Abstract][Full Text] [Related]
11. Combining biophysical screening and X-ray crystallography for fragment-based drug discovery. Hennig M; Ruf A; Huber W Top Curr Chem; 2012; 317():115-43. PubMed ID: 21837555 [TBL] [Abstract][Full Text] [Related]
12. Leveraging structural approaches: applications of NMR-based screening and X-ray crystallography for inhibitor design. Moore J; Abdul-Manan N; Fejzo J; Jacobs M; Lepre C; Peng J; Xie X J Synchrotron Radiat; 2004 Jan; 11(Pt 1):97-100. PubMed ID: 14646145 [TBL] [Abstract][Full Text] [Related]
13. Contributions of computational chemistry and biophysical techniques to fragment-based drug discovery. Gozalbes R; Carbajo RJ; Pineda-Lucena A Curr Med Chem; 2010; 17(17):1769-94. PubMed ID: 20345344 [TBL] [Abstract][Full Text] [Related]
14. Complementarity between in silico and biophysical screening approaches in fragment-based lead discovery against the A(2A) adenosine receptor. Chen D; Ranganathan A; IJzerman AP; Siegal G; Carlsson J J Chem Inf Model; 2013 Oct; 53(10):2701-14. PubMed ID: 23971943 [TBL] [Abstract][Full Text] [Related]
15. Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification. Kobayashi M; Retra K; Figaroa F; Hollander JG; Ab E; Heetebrij RJ; Irth H; Siegal G J Biomol Screen; 2010 Sep; 15(8):978-89. PubMed ID: 20817886 [TBL] [Abstract][Full Text] [Related]
16. NMR-Fragment Based Virtual Screening: A Brief Overview. Singh M; Tam B; Akabayov B Molecules; 2018 Jan; 23(2):. PubMed ID: 29370102 [TBL] [Abstract][Full Text] [Related]
17. Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics. Lau WF; Withka JM; Hepworth D; Magee TV; Du YJ; Bakken GA; Miller MD; Hendsch ZS; Thanabal V; Kolodziej SA; Xing L; Hu Q; Narasimhan LS; Love R; Charlton ME; Hughes S; van Hoorn WP; Mills JE J Comput Aided Mol Des; 2011 Jul; 25(7):621-36. PubMed ID: 21604056 [TBL] [Abstract][Full Text] [Related]
18. Design of compound libraries for fragment screening. Blomberg N; Cosgrove DA; Kenny PW; Kolmodin K J Comput Aided Mol Des; 2009 Aug; 23(8):513-25. PubMed ID: 19283339 [TBL] [Abstract][Full Text] [Related]