446 related articles for article (PubMed ID: 25989142)
1. The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes.
Wilkinson B; Grepo N; Thompson BL; Kim J; Wang K; Evgrafov OV; Lu W; Knowles JA; Campbell DB
Transl Psychiatry; 2015 May; 5(5):e568. PubMed ID: 25989142
[TBL] [Abstract][Full Text] [Related]
2. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment.
Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP
Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243
[TBL] [Abstract][Full Text] [Related]
3. CHD8 intragenic deletion associated with autism spectrum disorder.
Stolerman ES; Smith B; Chaubey A; Jones JR
Eur J Med Genet; 2016 Apr; 59(4):189-94. PubMed ID: 26921529
[TBL] [Abstract][Full Text] [Related]
4. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.
Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM
Mol Autism; 2017; 8():11. PubMed ID: 28321286
[TBL] [Abstract][Full Text] [Related]
5. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.
Shi X; Lu C; Corman A; Nikish A; Zhou Y; Platt RJ; Iossifov I; Zhang F; Pan JQ; Sanjana NE
Am J Hum Genet; 2023 Oct; 110(10):1750-1768. PubMed ID: 37802044
[TBL] [Abstract][Full Text] [Related]
6. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.
Sugathan A; Biagioli M; Golzio C; Erdin S; Blumenthal I; Manavalan P; Ragavendran A; Brand H; Lucente D; Miles J; Sheridan SD; Stortchevoi A; Kellis M; Haggarty SJ; Katsanis N; Gusella JF; Talkowski ME
Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4468-77. PubMed ID: 25294932
[TBL] [Abstract][Full Text] [Related]
7. Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants.
Siu MT; Butcher DT; Turinsky AL; Cytrynbaum C; Stavropoulos DJ; Walker S; Caluseriu O; Carter M; Lou Y; Nicolson R; Georgiades S; Szatmari P; Anagnostou E; Scherer SW; Choufani S; Brudno M; Weksberg R
Clin Epigenetics; 2019 Jul; 11(1):103. PubMed ID: 31311581
[TBL] [Abstract][Full Text] [Related]
8. Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle.
Coakley-Youngs E; Ranatunga M; Richardson S; Getti G; Shorter S; Fivaz M
Biol Open; 2022 Sep; 11(9):. PubMed ID: 36222238
[TBL] [Abstract][Full Text] [Related]
9. [Progress in autism: de novo mutation and CHD8 functions].
Xiong XX; He M; Chen XQ
Sheng Li Ke Xue Jin Zhan; 2014 Jun; 45(3):185-9. PubMed ID: 25219269
[TBL] [Abstract][Full Text] [Related]
10. Autism spectrum disorder early in development associated with CHD8 mutations among two Chinese children.
Wang J; Liu J; Gao Y; Wang K; Jiang K
BMC Pediatr; 2018 Oct; 18(1):338. PubMed ID: 30376831
[TBL] [Abstract][Full Text] [Related]
11. De novo variants in the Helicase-C domain of CHD8 are associated with severe phenotypes including autism, language disability and overgrowth.
An Y; Zhang L; Liu W; Jiang Y; Chen X; Lan X; Li G; Hang Q; Wang J; Gusella JF; Du Y; Shen Y
Hum Genet; 2020 Apr; 139(4):499-512. PubMed ID: 31980904
[TBL] [Abstract][Full Text] [Related]
12. Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons.
Kawamura A; Nishiyama M
Commun Biol; 2023 Jun; 6(1):593. PubMed ID: 37268684
[TBL] [Abstract][Full Text] [Related]
13. A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review.
Merner N; Forgeot d'Arc B; Bell SC; Maussion G; Peng H; Gauthier J; Crapper L; Hamdan FF; Michaud JL; Mottron L; Rouleau GA; Ernst C
Am J Med Genet A; 2016 May; 170A(5):1225-35. PubMed ID: 26789910
[TBL] [Abstract][Full Text] [Related]
14. CHD8 haploinsufficiency results in autistic-like phenotypes in mice.
Katayama Y; Nishiyama M; Shoji H; Ohkawa Y; Kawamura A; Sato T; Suyama M; Takumi T; Miyakawa T; Nakayama KI
Nature; 2016 Sep; 537(7622):675-679. PubMed ID: 27602517
[TBL] [Abstract][Full Text] [Related]
15. Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling.
Durak O; Gao F; Kaeser-Woo YJ; Rueda R; Martorell AJ; Nott A; Liu CY; Watson LA; Tsai LH
Nat Neurosci; 2016 Nov; 19(11):1477-1488. PubMed ID: 27694995
[TBL] [Abstract][Full Text] [Related]
16. Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
Modafferi S; Zhong X; Kleensang A; Murata Y; Fagiani F; Pamies D; Hogberg HT; Calabrese V; Lachman H; Hartung T; Smirnova L
Environ Health Perspect; 2021 Jul; 129(7):77001. PubMed ID: 34259569
[TBL] [Abstract][Full Text] [Related]
17. CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories.
Villa CE; Cheroni C; Dotter CP; López-Tóbon A; Oliveira B; Sacco R; Yahya AÇ; Morandell J; Gabriele M; Tavakoli MR; Lyudchik J; Sommer C; Gabitto M; Danzl JG; Testa G; Novarino G
Cell Rep; 2022 Apr; 39(1):110615. PubMed ID: 35385734
[TBL] [Abstract][Full Text] [Related]
18. The human chd8 gene is transcribed from two distant upstream promoters.
Kunkel GR; Lisciandro HG; Winter HL
Biochem Biophys Res Commun; 2020 Nov; 532(2):190-194. PubMed ID: 32854944
[TBL] [Abstract][Full Text] [Related]
19. The autism-associated protein CHD8 is required for cerebellar development and motor function.
Kawamura A; Katayama Y; Kakegawa W; Ino D; Nishiyama M; Yuzaki M; Nakayama KI
Cell Rep; 2021 Apr; 35(1):108932. PubMed ID: 33826902
[TBL] [Abstract][Full Text] [Related]
20. Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons.
Xu Q; Liu YY; Wang X; Tan GH; Li HP; Hulbert SW; Li CY; Hu CC; Xiong ZQ; Xu X; Jiang YH
Mol Autism; 2018; 9():65. PubMed ID: 30574290
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
