229 related articles for article (PubMed ID: 25989893)
1. Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug-drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys.
Watanabe M; Watanabe T; Yabuki M; Tamai I
Drug Metab Pharmacokinet; 2015 Apr; 30(2):198-204. PubMed ID: 25989893
[TBL] [Abstract][Full Text] [Related]
2. Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions.
Nishizawa K; Nakanishi T; Tamai I
Drug Metab Dispos; 2017 Feb; 45(2):224-227. PubMed ID: 27934638
[TBL] [Abstract][Full Text] [Related]
3. Pitavastatin as an in vivo probe for studying hepatic organic anion transporting polypeptide-mediated drug-drug interactions in cynomolgus monkeys.
Takahashi T; Ohtsuka T; Yoshikawa T; Tatekawa I; Uno Y; Utoh M; Yamazaki H; Kume T
Drug Metab Dispos; 2013 Oct; 41(10):1875-82. PubMed ID: 23929936
[TBL] [Abstract][Full Text] [Related]
4. Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation.
Shen H; Yang Z; Mintier G; Han YH; Chen C; Balimane P; Jemal M; Zhao W; Zhang R; Kallipatti S; Selvam S; Sukrutharaj S; Krishnamurthy P; Marathe P; Rodrigues AD
J Pharmacol Exp Ther; 2013 Mar; 344(3):673-85. PubMed ID: 23297161
[TBL] [Abstract][Full Text] [Related]
5. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.
Niu C; Wang Y; Zhao X; Tep S; Murakami E; Subramanian R; Smith B; Lai Y
Drug Metab Dispos; 2019 Dec; 47(12):1433-1442. PubMed ID: 31582395
[TBL] [Abstract][Full Text] [Related]
6. Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
Thakare R; Gao H; Kosa RE; Bi YA; Varma MVS; Cerny MA; Sharma R; Kuhn M; Huang B; Liu Y; Yu A; Walker GS; Niosi M; Tremaine L; Alnouti Y; Rodrigues AD
Drug Metab Dispos; 2017 Jul; 45(7):721-733. PubMed ID: 28396527
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.
Chu X; Shih SJ; Shaw R; Hentze H; Chan GH; Owens K; Wang S; Cai X; Newton D; Castro-Perez J; Salituro G; Palamanda J; Fernandis A; Ng CK; Liaw A; Savage MJ; Evers R
Drug Metab Dispos; 2015 Jun; 43(6):851-63. PubMed ID: 25813937
[TBL] [Abstract][Full Text] [Related]
8. In Vitro-In Vivo Extrapolation of OATP1B-Mediated Drug-Drug Interactions in Cynomolgus Monkey.
Ufuk A; Kosa RE; Gao H; Bi YA; Modi S; Gates D; Rodrigues AD; Tremaine LM; Varma MVS; Houston JB; Galetin A
J Pharmacol Exp Ther; 2018 Jun; 365(3):688-699. PubMed ID: 29643253
[TBL] [Abstract][Full Text] [Related]
9. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects.
Shen H; Chen W; Drexler DM; Mandlekar S; Holenarsipur VK; Shields EE; Langish R; Sidik K; Gan J; Humphreys WG; Marathe P; Lai Y
Drug Metab Dispos; 2017 Aug; 45(8):908-919. PubMed ID: 28576766
[TBL] [Abstract][Full Text] [Related]
10. Pre-incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide.
Takahashi T; Ohtsuka T; Uno Y; Utoh M; Yamazaki H; Kume T
Biopharm Drug Dispos; 2016 Nov; 37(8):479-490. PubMed ID: 27603548
[TBL] [Abstract][Full Text] [Related]
11. Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.
Shen H; Su H; Liu T; Yao M; Mintier G; Li L; Fancher RM; Iyer R; Marathe P; Lai Y; Rodrigues AD
J Pharmacol Exp Ther; 2015 May; 353(2):380-91. PubMed ID: 25740896
[TBL] [Abstract][Full Text] [Related]
12. Predicting Human Clearance of Organic Anion Transporting Polypeptide Substrates Using Cynomolgus Monkey: In Vitro-In Vivo Scaling of Hepatic Uptake Clearance.
De Bruyn T; Ufuk A; Cantrill C; Kosa RE; Bi YA; Niosi M; Modi S; Rodrigues AD; Tremaine LM; Varma MVS; Galetin A; Houston JB
Drug Metab Dispos; 2018 Jul; 46(7):989-1000. PubMed ID: 29720472
[TBL] [Abstract][Full Text] [Related]
13. Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver.
Vavricka SR; Van Montfoort J; Ha HR; Meier PJ; Fattinger K
Hepatology; 2002 Jul; 36(1):164-72. PubMed ID: 12085361
[TBL] [Abstract][Full Text] [Related]
14. Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.
Lau YY; Okochi H; Huang Y; Benet LZ
Drug Metab Dispos; 2006 Jul; 34(7):1175-81. PubMed ID: 16624870
[TBL] [Abstract][Full Text] [Related]
15. Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin.
Prueksaritanont T; Chu X; Evers R; Klopfer SO; Caro L; Kothare PA; Dempsey C; Rasmussen S; Houle R; Chan G; Cai X; Valesky R; Fraser IP; Stoch SA
Br J Clin Pharmacol; 2014 Sep; 78(3):587-98. PubMed ID: 24617605
[TBL] [Abstract][Full Text] [Related]
16. Characterization of Long-Lasting Oatp Inhibition by Typical Inhibitor Cyclosporine A and In Vitro-In Vivo Discrepancy in Its Drug Interaction Potential in Rats.
Taguchi T; Masuo Y; Kogi T; Nakamichi N; Kato Y
J Pharm Sci; 2016 Jul; 105(7):2231-9. PubMed ID: 27290622
[TBL] [Abstract][Full Text] [Related]
17. Integrated approach of in vivo and in vitro evaluation of the involvement of hepatic uptake organic anion transporters in the drug disposition in rats using rifampicin as an inhibitor.
Imaoka T; Mikkaichi T; Abe K; Hirouchi M; Okudaira N; Izumi T
Drug Metab Dispos; 2013 Jul; 41(7):1442-9. PubMed ID: 23640987
[TBL] [Abstract][Full Text] [Related]
18. [Development of Prediction Methods for Drug-Drug Interactions Based on the Construction of Physiologically Based Pharmacokinetic Models for Hepatic OATP Substrate Drugs and Endogenous Substrates].
Yoshikado T
Yakugaku Zasshi; 2023; 143(1):11-19. PubMed ID: 36596534
[TBL] [Abstract][Full Text] [Related]
19. Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.
Gu X; Wang L; Gan J; Fancher RM; Tian Y; Hong Y; Lai Y; Sinz M; Shen H
Drug Metab Dispos; 2020 Aug; 48(8):724-734. PubMed ID: 32482623
[TBL] [Abstract][Full Text] [Related]
20. Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species.
Shen H; Dai J; Liu T; Cheng Y; Chen W; Freeden C; Zhang Y; Humphreys WG; Marathe P; Lai Y
J Pharmacol Exp Ther; 2016 May; 357(2):382-93. PubMed ID: 26907622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
