BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 25997440)

  • 1. The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.
    Spann AL; Yuan K; Goliwas KF; Steg AD; Kaushik DD; Kwon YJ; Frost AR
    Int J Oncol; 2015 Jul; 47(1):269-79. PubMed ID: 25997440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
    Arnhold V; Boos J; Lanvers-Kaminsky C
    Cancer Chemother Pharmacol; 2016 Mar; 77(3):495-505. PubMed ID: 26781311
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Nedd4 as a novel regulator in Hedgehog signaling.
    Luo QF; Chen W; Zhang ST
    Chin Med J (Engl); 2012 Nov; 125(21):3851-5. PubMed ID: 23106887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?
    Ruiz i Altaba A
    Cancer Cell; 2008 Oct; 14(4):281-3. PubMed ID: 18835029
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; FuskevÄg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
    Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small-molecule modulators of the Sonic Hedgehog signaling pathway.
    Stanton BZ; Peng LF
    Mol Biosyst; 2010 Jan; 6(1):44-54. PubMed ID: 20024066
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The primary cilia, a 'Rab-id' transit system for hedgehog signaling.
    Oro AE
    Curr Opin Cell Biol; 2007 Dec; 19(6):691-6. PubMed ID: 18061425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.
    Tukachinsky H; Lopez LV; Salic A
    J Cell Biol; 2010 Oct; 191(2):415-28. PubMed ID: 20956384
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The path to chemotaxis and transcription is smoothened.
    Lin C; Nozawa YI; Chuang PT
    Sci Signal; 2012 Aug; 5(238):pe35. PubMed ID: 22912492
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nonclassical hedgehog-GLI signaling and its clinical implications.
    Shevde LA; Samant RS
    Int J Cancer; 2014 Jul; 135(1):1-6. PubMed ID: 23929208
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction.
    Gorojankina T
    Cell Mol Life Sci; 2016 Apr; 73(7):1317-32. PubMed ID: 26762301
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sonic hedgehog stimulates glycolysis and proliferation of breast cancer cells: Modulation of PFKFB3 activation.
    Ge X; Lyu P; Gu Y; Li L; Li J; Wang Y; Zhang L; Fu C; Cao Z
    Biochem Biophys Res Commun; 2015 Aug; 464(3):862-8. PubMed ID: 26171876
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hedgehog signaling is synergistically enhanced by nutritional deprivation and ligand stimulation in human fibroblasts of Gorlin syndrome.
    Mizuochi H; Fujii K; Shiohama T; Uchikawa H; Shimojo N
    Biochem Biophys Res Commun; 2015 Feb; 457(3):318-23. PubMed ID: 25576868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
    Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
    Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting GLI factors to inhibit the Hedgehog pathway.
    Infante P; Alfonsi R; Botta B; Mori M; Di Marcotullio L
    Trends Pharmacol Sci; 2015 Aug; 36(8):547-58. PubMed ID: 26072120
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
    Lee H; Ko HW
    Biochem Biophys Res Commun; 2016 Nov; 480(4):574-579. PubMed ID: 27793670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cilia and Hedgehog responsiveness in the mouse.
    Huangfu D; Anderson KV
    Proc Natl Acad Sci U S A; 2005 Aug; 102(32):11325-30. PubMed ID: 16061793
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Hedgehog Signaling in Fibroblasts, Pancreatic, and Lung Tumor Cells by Oxy186, an Oxysterol Analogue with Drug-Like Properties.
    Wang F; Stappenbeck F; Parhami F
    Cells; 2019 May; 8(5):. PubMed ID: 31137846
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Noncanonical regulation of the Hedgehog mediator GLI1 by c-MYC in Burkitt lymphoma.
    Yoon JW; Gallant M; Lamm ML; Iannaccone S; Vieux KF; Proytcheva M; Hyjek E; Iannaccone P; Walterhouse D
    Mol Cancer Res; 2013 Jun; 11(6):604-15. PubMed ID: 23525267
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.