262 related articles for article (PubMed ID: 25997742)
1. Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease.
Erie C; Sacino M; Houle L; Lu ML; Wei J
Eur J Neurosci; 2015 Aug; 42(3):1941-51. PubMed ID: 25997742
[TBL] [Abstract][Full Text] [Related]
2. Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.
Pryor WM; Biagioli M; Shahani N; Swarnkar S; Huang WC; Page DT; MacDonald ME; Subramaniam S
Sci Signal; 2014 Oct; 7(349):ra103. PubMed ID: 25351248
[TBL] [Abstract][Full Text] [Related]
3. Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.
Kegel KB; Kim M; Sapp E; McIntyre C; Castaño JG; Aronin N; DiFiglia M
J Neurosci; 2000 Oct; 20(19):7268-78. PubMed ID: 11007884
[TBL] [Abstract][Full Text] [Related]
4. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
Lee H; Noh JY; Oh Y; Kim Y; Chang JW; Chung CW; Lee ST; Kim M; Ryu H; Jung YK
Hum Mol Genet; 2012 Jan; 21(1):101-14. PubMed ID: 21954231
[TBL] [Abstract][Full Text] [Related]
5. Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.
Ribeiro M; Rosenstock TR; Cunha-Oliveira T; Ferreira IL; Oliveira CR; Rego AC
Free Radic Biol Med; 2012 Nov; 53(10):1857-67. PubMed ID: 22982598
[TBL] [Abstract][Full Text] [Related]
6. Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice.
McClory H; Williams D; Sapp E; Gatune LW; Wang P; DiFiglia M; Li X
Acta Neuropathol Commun; 2014 Dec; 2():179. PubMed ID: 25526803
[TBL] [Abstract][Full Text] [Related]
7. Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes.
Lee JH; Tecedor L; Chen YH; Monteys AM; Sowada MJ; Thompson LM; Davidson BL
Neuron; 2015 Jan; 85(2):303-15. PubMed ID: 25556834
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of GSK-3 ameliorates the pathogenesis of Huntington's disease.
Rippin I; Bonder K; Joseph S; Sarsor A; Vaks L; Eldar-Finkelman H
Neurobiol Dis; 2021 Jul; 154():105336. PubMed ID: 33753290
[TBL] [Abstract][Full Text] [Related]
9. Accumulation of autophagosomes confers cytotoxicity.
Button RW; Roberts SL; Willis TL; Hanemann CO; Luo S
J Biol Chem; 2017 Aug; 292(33):13599-13614. PubMed ID: 28673965
[TBL] [Abstract][Full Text] [Related]
10. Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid.
Vodicka P; Mo S; Tousley A; Green KM; Sapp E; Iuliano M; Sadri-Vakili G; Shaffer SA; Aronin N; DiFiglia M; Kegel-Gleason KB
J Huntingtons Dis; 2015; 4(2):187-201. PubMed ID: 26397899
[TBL] [Abstract][Full Text] [Related]
11. Deletion of SUMO1 attenuates behavioral and anatomical deficits by regulating autophagic activities in Huntington disease.
Ramírez-Jarquín UN; Sharma M; Zhou W; Shahani N; Subramaniam S
Proc Natl Acad Sci U S A; 2022 Feb; 119(5):. PubMed ID: 35086928
[TBL] [Abstract][Full Text] [Related]
12. Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington's disease patients.
Pierzynowska K; Gaffke L; Cyske Z; Węgrzyn G
Metab Brain Dis; 2019 Jun; 34(3):715-720. PubMed ID: 30850940
[TBL] [Abstract][Full Text] [Related]
13. Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease.
Valionyte E; Yang Y; Roberts SL; Kelly J; Lu B; Luo S
J Mol Biol; 2020 Apr; 432(8):2673-2691. PubMed ID: 31786267
[TBL] [Abstract][Full Text] [Related]
14. ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.
Wold MS; Lim J; Lachance V; Deng Z; Yue Z
Mol Neurodegener; 2016 Dec; 11(1):76. PubMed ID: 27938392
[TBL] [Abstract][Full Text] [Related]
15. The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity.
Camnasio S; Delli Carri A; Lombardo A; Grad I; Mariotti C; Castucci A; Rozell B; Lo Riso P; Castiglioni V; Zuccato C; Rochon C; Takashima Y; Diaferia G; Biunno I; Gellera C; Jaconi M; Smith A; Hovatta O; Naldini L; Di Donato S; Feki A; Cattaneo E
Neurobiol Dis; 2012 Apr; 46(1):41-51. PubMed ID: 22405424
[TBL] [Abstract][Full Text] [Related]
16. Atg4b-dependent autophagic flux alleviates Huntington's disease progression.
Proenca CC; Stoehr N; Bernhard M; Seger S; Genoud C; Roscic A; Paganetti P; Liu S; Murphy LO; Kuhn R; Bouwmeester T; Galimberti I
PLoS One; 2013; 8(7):e68357. PubMed ID: 23861892
[TBL] [Abstract][Full Text] [Related]
17. VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.
Guo X; Qi X
Biochim Biophys Acta Mol Basis Dis; 2017 Feb; 1863(2):552-559. PubMed ID: 27913212
[TBL] [Abstract][Full Text] [Related]
18. Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy.
Chang R; Liu X; Li S; Li XJ
Drug Des Devel Ther; 2015; 9():2179-88. PubMed ID: 25931812
[TBL] [Abstract][Full Text] [Related]
19. Lysosomal positioning coordinates cellular nutrient responses.
Korolchuk VI; Saiki S; Lichtenberg M; Siddiqi FH; Roberts EA; Imarisio S; Jahreiss L; Sarkar S; Futter M; Menzies FM; O'Kane CJ; Deretic V; Rubinsztein DC
Nat Cell Biol; 2011 Apr; 13(4):453-60. PubMed ID: 21394080
[TBL] [Abstract][Full Text] [Related]
20. Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein.
Qi L; Zhang XD
Acta Biochim Biophys Sin (Shanghai); 2014 Feb; 46(2):83-91. PubMed ID: 24323530
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
