These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 26011121)

  • 1. Atomic Insight into the Altered O6-Methylguanine-DNA Methyltransferase Protein Architecture in Gastric Cancer.
    Chikan NA; Bukhari S; Shabir N; Amin A; Shafi S; Qadri RA; Patel TN
    PLoS One; 2015; 10(5):e0127741. PubMed ID: 26011121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specific recognition of O6-methylguanine in DNA by active site mutants of human O6-methylguanine-DNA methyltransferase.
    Hazra TK; Roy R; Biswas T; Grabowski DT; Pegg AE; Mitra S
    Biochemistry; 1997 May; 36(19):5769-76. PubMed ID: 9153417
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A polymorphism at codon 160 of human O6-methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay.
    Imai Y; Oda H; Nakatsuru Y; Ishikawa T
    Carcinogenesis; 1995 Oct; 16(10):2441-5. PubMed ID: 7586149
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a "salt-link".
    Oh HK; Teo AK; Ali RB; Lim A; Ayi TC; Yarosh DB; Li BF
    Biochemistry; 1996 Sep; 35(38):12259-66. PubMed ID: 8823159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of O6-methylguanine DNA methyltransferase activity in patients with gastric cancer.
    Dinçer Y; Akçay T; Tortum OB; Alademir Z; Onen S; Doğusoy G
    Oncol Res; 2003; 13(4):205-9. PubMed ID: 12659421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms.
    Schwarzl SM; Smith JC; Kaina B; Efferth T
    Int J Mol Med; 2005 Oct; 16(4):553-7. PubMed ID: 16142386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hyperthermostable protein structure maintained by intra and inter-helix ion-pairs in archaeal O6-methylguanine-DNA methyltransferase.
    Hashimoto H; Inoue T; Nishioka M; Fujiwara S; Takagi M; Imanaka T; Kai Y
    J Mol Biol; 1999 Sep; 292(3):707-16. PubMed ID: 10497033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Factors influencing the repair of the mutagenic lesion O6-methylguanine in DNA by human O6-methylguanine-DNA methyltransferase.
    Liem LK; Wong CW; Lim A; Li BF
    J Mol Biol; 1993 Jun; 231(4):950-9. PubMed ID: 8515475
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Esteller M; Toyota M; Sanchez-Cespedes M; Capella G; Peinado MA; Watkins DN; Issa JP; Sidransky D; Baylin SB; Herman JG
    Cancer Res; 2000 May; 60(9):2368-71. PubMed ID: 10811111
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of O6-methylguanine-DNA methyltransferase in soft tissue sarcomas: association with K-ras mutations.
    Kim JI; Suh JT; Choi KU; Kang HJ; Shin DH; Lee IS; Moon TY; Kim WT
    Hum Pathol; 2009 Jul; 40(7):934-41. PubMed ID: 19356788
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
    Yang JL; Hsieh FP; Lee PC; Tseng HJ
    Cancer Res; 1994 Jul; 54(14):3857-63. PubMed ID: 8033107
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An O6-methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein.
    Morita R; Nakagawa N; Kuramitsu S; Masui R
    J Biochem; 2008 Aug; 144(2):267-77. PubMed ID: 18483064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma.
    Kohya N; Kitajima Y; Kitahara K; Miyazaki K
    Int J Mol Med; 2003 Jan; 11(1):65-9. PubMed ID: 12469220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase.
    Roberts A; Pelton JG; Wemmer DE
    Magn Reson Chem; 2006 Jul; 44 Spec No():S71-82. PubMed ID: 16826543
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O6-methylguanine-DNA methyltransferase deficiency in developing brain: implications for brain tumorigenesis.
    Bobola MS; Blank A; Berger MS; Silber JR
    DNA Repair (Amst); 2007 Aug; 6(8):1127-33. PubMed ID: 17500046
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate specificity of human O6-methylguanine-DNA methyltransferase for O6-benzylguanine derivatives in oligodeoxynucleotides.
    Terashima I; Kawate H; Sakumi K; Sekiguchi M; Kohda K
    Chem Res Toxicol; 1997 Nov; 10(11):1234-9. PubMed ID: 9403175
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J; Kaina B
    Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.
    Bae SI; Lee HS; Kim SH; Kim WH
    Br J Cancer; 2002 Jun; 86(12):1888-92. PubMed ID: 12085181
    [TBL] [Abstract][Full Text] [Related]  

  • 19. O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma.
    Zuo C; Ai L; Ratliff P; Suen JY; Hanna E; Brent TP; Fan CY
    Cancer Epidemiol Biomarkers Prev; 2004 Jun; 13(6):967-75. PubMed ID: 15184253
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Mutation of human O6-alkylguanine-DNA alkyltransferase confers resistance to O6-benzylguanine].
    Wan Y; Wu D; Gao H
    Zhonghua Zhong Liu Za Zhi; 2000 Jul; 22(4):290-3. PubMed ID: 11778552
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.