BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 26012882)

  • 1. Modulation of Retinoic Acid Receptor Subtypes by 5- and 8-Substituted (Naphthalen-2-yl)-based Arotinoids.
    Álvarez S; Lieb M; Martínez C; Khanwalkar H; Rodríguez-Barrios F; Álvarez R; Gronemeyer H; de Lera AR
    ChemMedChem; 2015 Aug; 10(8):1378-91. PubMed ID: 26012882
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C3 halogen and c8'' substituents on stilbene arotinoids modulate retinoic Acid receptor subtype function.
    Alvarez S; Khanwalkar H; Alvarez R; Erb C; Martínez C; Rodríguez-Barrios F; Germain P; Gronemeyer H; de Lera AR
    ChemMedChem; 2009 Oct; 4(10):1630-40. PubMed ID: 19670208
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pyrazine arotinoids with inverse agonist activities on the retinoid and rexinoid receptors.
    García J; Khanwalkar H; Pereira R; Erb C; Voegel JJ; Collette P; Mauvais P; Bourguet W; Gronemeyer H; de Lera AR
    Chembiochem; 2009 May; 10(7):1252-9. PubMed ID: 19343742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retinoic acid receptor beta,gamma-selective ligands: synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids.
    Yu KL; Spinazze P; Ostrowski J; Currier SJ; Pack EJ; Hammer L; Roalsvig T; Honeyman JA; Tortolani DR; Reczek PR; Mansuri MM; Starrett JE
    J Med Chem; 1996 Jun; 39(12):2411-21. PubMed ID: 8691435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of highly potent retinoic acid receptor alpha-selective antagonists.
    Teng M; Duong TT; Johnson AT; Klein ES; Wang L; Khalifa B; Chandraratna RA
    J Med Chem; 1997 Aug; 40(16):2445-51. PubMed ID: 9258350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the differential coregulator binding signatures of the Retinoic Acid Receptor subtypes upon (ant)agonist action.
    Miro Estruch I; Melchers D; Houtman R; de Haan LHJ; Groten JP; Louisse J; Rietjens IMCM
    Biochim Biophys Acta Proteins Proteom; 2017 Sep; 1865(9):1195-1206. PubMed ID: 28642153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
    Géhin M; Vivat V; Wurtz JM; Losson R; Chambon P; Moras D; Gronemeyer H
    Chem Biol; 1999 Aug; 6(8):519-29. PubMed ID: 10421757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Critical role of the H6-H7 loop in the conformational adaptation of all-trans retinoic acid and synthetic retinoids within the ligand-binding site of RARalpha.
    Mailfait S; Thoreau E; Belaiche D; Formstecher And B Sablonniè P
    J Mol Endocrinol; 2000 Jun; 24(3):353-64. PubMed ID: 10828828
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of Ser(289) in RARgamma and its homologous amino acid residue of RARalpha and RARbeta in the binding of retinoic acid.
    Zhang ZP; Shukri M; Gambone CJ; Gabriel JL; Soprano KJ; Soprano DR
    Arch Biochem Biophys; 2000 Aug; 380(2):339-46. PubMed ID: 10933889
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Syntheses and structure-activity relationships of 5,6,7, 8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxaline derivatives with retinoic acid receptor alpha agonistic activity.
    Kikuchi K; Hibi S; Yoshimura H; Tokuhara N; Tai K; Hida T; Yamauchi T; Nagai M
    J Med Chem; 2000 Feb; 43(3):409-19. PubMed ID: 10669568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual RXR Agonists and RAR Antagonists Based on the Stilbene Retinoid Scaffold.
    Martínez C; Lieb M; Alvarez S; Rodríguez-Barrios F; Alvarez R; Khanwalkar H; Gronemeyer H; de Lera AR
    ACS Med Chem Lett; 2014 May; 5(5):533-7. PubMed ID: 24900875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Retinoic acid receptor modulators: a perspective on recent advances and promises.
    Alvarez S; Bourguet W; Gronemeyer H; de Lera AR
    Expert Opin Ther Pat; 2011 Jan; 21(1):55-63. PubMed ID: 21091043
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of retinoid-induced differentiation in embryonal carcinoma PCC4.aza1R cells: effects of retinoid-receptor selective ligands.
    Mills KJ; Vollberg TM; Nervi C; Grippo JF; Dawson MI; Jetten AM
    Cell Growth Differ; 1996 Mar; 7(3):327-37. PubMed ID: 8838863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative teratogenic activity of cancer chemopreventive retinoidal benzoic acid congeners (arotinoids).
    Flanagan JL; Willhite CC; Ferm VH
    J Natl Cancer Inst; 1987 Mar; 78(3):533-8. PubMed ID: 3469465
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and stereoselective synthesis of retinoids with ferrocene or N-butylcarbazole pharmacophores that induce post-differentiation apoptosis in acute promyelocytic leukemia cells.
    Ivanova D; Gronemeyer H; de Lera AR
    ChemMedChem; 2011 Aug; 6(8):1518-29. PubMed ID: 21506276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists.
    Germain P; Gaudon C; Pogenberg V; Sanglier S; Van Dorsselaer A; Royer CA; Lazar MA; Bourguet W; Gronemeyer H
    Chem Biol; 2009 May; 16(5):479-89. PubMed ID: 19477412
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disila-analogues of the synthetic retinoids EC23 and TTNN: synthesis, structure and biological evaluation.
    Gluyas JB; Burschka C; Dörrich S; Vallet J; Gronemeyer H; Tacke R
    Org Biomol Chem; 2012 Sep; 10(34):6914-29. PubMed ID: 22814352
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anticoagulant effects of synthetic retinoids and activated vitamin D3.
    Koyama T; Hirosawa S
    Semin Thromb Hemost; 1998; 24(3):217-26. PubMed ID: 9701451
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells.
    Zhuang Y; Faria TN; Chambon P; Gudas LJ
    Mol Cancer Res; 2003 Jun; 1(8):619-30. PubMed ID: 12805409
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor.
    Altucci L; Rossin A; Hirsch O; Nebbioso A; Vitoux D; Wilhelm E; Guidez F; De Simone M; Schiavone EM; Grimwade D; Zelent A; de Thé H; Gronemeyer H
    Cancer Res; 2005 Oct; 65(19):8754-65. PubMed ID: 16204045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.