BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 26014385)

  • 21. Regulation of physiologic actions of LRRK2: focus on autophagy.
    Ferree A; Guillily M; Li H; Smith K; Takashima A; Squillace R; Weigele M; Collins JJ; Wolozin B
    Neurodegener Dis; 2012; 10(1-4):238-41. PubMed ID: 22204929
    [TBL] [Abstract][Full Text] [Related]  

  • 22. LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth.
    Kawakami F; Yabata T; Ohta E; Maekawa T; Shimada N; Suzuki M; Maruyama H; Ichikawa T; Obata F
    PLoS One; 2012; 7(1):e30834. PubMed ID: 22303461
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm.
    Esteves AR; G-Fernandes M; Santos D; Januário C; Cardoso SM
    Mol Neurobiol; 2015 Dec; 52(3):1804-1820. PubMed ID: 25394383
    [TBL] [Abstract][Full Text] [Related]  

  • 24. ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression.
    Zhu Y; Wang C; Yu M; Cui J; Liu L; Xu Z
    Protein Cell; 2013 Sep; 4(9):711-21. PubMed ID: 27023913
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The Parkinson's disease protein LRRK2 impairs proteasome substrate clearance without affecting proteasome catalytic activity.
    Lichtenberg M; Mansilla A; Zecchini VR; Fleming A; Rubinsztein DC
    Cell Death Dis; 2011 Aug; 2(8):e196. PubMed ID: 21866175
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Designing antibodies against LRRK2-targeted tau epitopes.
    Hamm M; Ladd TB; Levites Y; Golde TE; Giasson BI; Lewis J
    PLoS One; 2018; 13(9):e0204367. PubMed ID: 30261006
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation.
    Miklossy J; Qing H; Guo JP; Yu S; Wszolek ZK; Calne D; McGeer EG; McGeer PL
    Acta Neuropathol; 2007 Sep; 114(3):243-54. PubMed ID: 17639429
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
    Melrose HL; Dächsel JC; Behrouz B; Lincoln SJ; Yue M; Hinkle KM; Kent CB; Korvatska E; Taylor JP; Witten L; Liang YQ; Beevers JE; Boules M; Dugger BN; Serna VA; Gaukhman A; Yu X; Castanedes-Casey M; Braithwaite AT; Ogholikhan S; Yu N; Bass D; Tyndall G; Schellenberg GD; Dickson DW; Janus C; Farrer MJ
    Neurobiol Dis; 2010 Dec; 40(3):503-17. PubMed ID: 20659558
    [TBL] [Abstract][Full Text] [Related]  

  • 29. LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
    Bae EJ; Kim DK; Kim C; Mante M; Adame A; Rockenstein E; Ulusoy A; Klinkenberg M; Jeong GR; Bae JR; Lee C; Lee HJ; Lee BD; Di Monte DA; Masliah E; Lee SJ
    Nat Commun; 2018 Aug; 9(1):3465. PubMed ID: 30150626
    [TBL] [Abstract][Full Text] [Related]  

  • 30. [Clinical molecular genetics for PARK8 (LRRK2)].
    Tomiyama H; Hatano T; Hattori N
    Brain Nerve; 2007 Aug; 59(8):839-50. PubMed ID: 17713120
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Parkinsonism, Lrrk2 G2019S, and tau neuropathology.
    Rajput A; Dickson DW; Robinson CA; Ross OA; Dächsel JC; Lincoln SJ; Cobb SA; Rajput ML; Farrer MJ
    Neurology; 2006 Oct; 67(8):1506-8. PubMed ID: 17060589
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Physiological and pathological functions of LRRK2: implications from substrate proteins.
    Araki M; Ito G; Tomita T
    Neuronal Signal; 2018 Dec; 2(4):NS20180005. PubMed ID: 32714591
    [TBL] [Abstract][Full Text] [Related]  

  • 33. LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3ß.
    Lin CH; Tsai PI; Wu RM; Chien CT
    J Neurosci; 2010 Sep; 30(39):13138-49. PubMed ID: 20881132
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cognitive enhancement, TAU phosphorylation reduction, and neuronal protection by the treatment of an LRRK2 inhibitor in a tauopathy mouse model.
    Castro-Sánchez S; Zaldivar-Diez J; Luengo E; López MG; Gil C; Martínez A; Lastres-Becker I
    Neurobiol Aging; 2020 Dec; 96():148-154. PubMed ID: 33007689
    [TBL] [Abstract][Full Text] [Related]  

  • 35. LRRK2 and neurodegeneration.
    Santpere G; Ferrer I
    Acta Neuropathol; 2009 Mar; 117(3):227-46. PubMed ID: 19142648
    [TBL] [Abstract][Full Text] [Related]  

  • 36. LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity.
    Heo HY; Park JM; Kim CH; Han BS; Kim KS; Seol W
    Exp Cell Res; 2010 Feb; 316(4):649-56. PubMed ID: 19769964
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Co-occurrence of sporadic parkinsonism and late-onset Alzheimer's disease in a Brazilian male with the LRRK2 p.G2019S mutation.
    Santos-Rebouças CB; Abdalla CB; Baldi FJ; Martins PA; Corrêa JC; Gonçalves AP; Cunha MS; Borges MB; Pereira JS; Laks J; Pimentel MM
    Genet Test; 2008 Dec; 12(4):471-3. PubMed ID: 19072560
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Neurodegenerative CSF markers in genetic and sporadic PD: Classification and prediction in a longitudinal study.
    Brockmann K; Schulte C; Deuschle C; Hauser AK; Heger T; Gasser T; Maetzler W; Berg D
    Parkinsonism Relat Disord; 2015 Dec; 21(12):1427-34. PubMed ID: 26475624
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Wild-type and mutant (G2019S) leucine-rich repeat kinase 2 (LRRK2) associate with subunits of the translocase of outer mitochondrial membrane (TOM) complex.
    Neethling A; Engelbrecht L; Loos B; Kinnear C; Theart R; Abrahams S; Niesler T; Mellick GD; Williams M; Bardien S
    Exp Cell Res; 2019 Feb; 375(2):72-79. PubMed ID: 30597143
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations.
    Sheng Z; Zhang S; Bustos D; Kleinheinz T; Le Pichon CE; Dominguez SL; Solanoy HO; Drummond J; Zhang X; Ding X; Cai F; Song Q; Li X; Yue Z; van der Brug MP; Burdick DJ; Gunzner-Toste J; Chen H; Liu X; Estrada AA; Sweeney ZK; Scearce-Levie K; Moffat JG; Kirkpatrick DS; Zhu H
    Sci Transl Med; 2012 Dec; 4(164):164ra161. PubMed ID: 23241745
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.