179 related articles for article (PubMed ID: 26019056)
1. Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.
Prabhakar S; Zhang X; Goto J; Han S; Lai C; Bronson R; Sena-Esteves M; Ramesh V; Stemmer-Rachamimov A; Kwiatkowski DJ; Breakefield XO
Neurobiol Dis; 2015 Oct; 82():22-31. PubMed ID: 26019056
[TBL] [Abstract][Full Text] [Related]
2. Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1.
Prabhakar S; Cheah PS; Zhang X; Zinter M; Gianatasio M; Hudry E; Bronson RT; Kwiatkowski DJ; Stemmer-Rachamimov A; Maguire CA; Sena-Esteves M; Tannous BA; Breakefield XO
Mol Ther Methods Clin Dev; 2019 Dec; 15():18-26. PubMed ID: 31534984
[TBL] [Abstract][Full Text] [Related]
3. Stochastic model of Tsc1 lesions in mouse brain.
Prabhakar S; Goto J; Zhang X; Sena-Esteves M; Bronson R; Brockmann J; Gianni D; Wojtkiewicz GR; Chen JW; Stemmer-Rachamimov A; Kwiatkowski DJ; Breakefield XO
PLoS One; 2013; 8(5):e64224. PubMed ID: 23696872
[TBL] [Abstract][Full Text] [Related]
4. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery.
Brown AB; Mahmood U; Cortes ML; Tang Y; Dai G; Stemmer-Rachamimov A; Prabhakar S; Leishear K; Onda H; Kwiatkowski D; Weissleder R; Breakefield X
Hum Gene Ther; 2005 Dec; 16(12):1367-76. PubMed ID: 16390268
[TBL] [Abstract][Full Text] [Related]
5. Minute amounts of hamartin wildtype rescue the emergence of tuber-like lesions in conditional Tsc1 ablated mice.
Robens BK; Grote A; Pitsch J; Schoch S; Cardoso C; Becker AJ
Neurobiol Dis; 2016 Nov; 95():134-44. PubMed ID: 27425891
[TBL] [Abstract][Full Text] [Related]
6. A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival.
Meikle L; Talos DM; Onda H; Pollizzi K; Rotenberg A; Sahin M; Jensen FE; Kwiatkowski DJ
J Neurosci; 2007 May; 27(21):5546-58. PubMed ID: 17522300
[TBL] [Abstract][Full Text] [Related]
7. A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma.
Wilson C; Idziaszczyk S; Parry L; Guy C; Griffiths DF; Lazda E; Bayne RA; Smith AJ; Sampson JR; Cheadle JP
Hum Mol Genet; 2005 Jul; 14(13):1839-50. PubMed ID: 15888477
[TBL] [Abstract][Full Text] [Related]
8. Comparative analysis of Tsc1 and Tsc2 single and double radial glial cell mutants.
Mietzsch U; McKenna J; Reith RM; Way SW; Gambello MJ
J Comp Neurol; 2013 Nov; 521(16):3817-31. PubMed ID: 23749404
[TBL] [Abstract][Full Text] [Related]
9. Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features.
Yuan E; Tsai PT; Greene-Colozzi E; Sahin M; Kwiatkowski DJ; Malinowska IA
Hum Mol Genet; 2012 Oct; 21(19):4286-300. PubMed ID: 22752306
[TBL] [Abstract][Full Text] [Related]
10. Expression of tuberin and hamartin in tuberous sclerosis complex-associated and sporadic cortical dysplasia of Taylor's balloon cell type.
Grajkowska W; Kotulska K; Matyja E; Larysz-Brysz M; Mandera M; Roszkowski M; Domańska-Pakieła D; Lewik-Kowalik J; Jóźwiak S
Folia Neuropathol; 2008; 46(1):43-8. PubMed ID: 18368626
[TBL] [Abstract][Full Text] [Related]
11. The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas.
Plank TL; Logginidou H; Klein-Szanto A; Henske EP
Mod Pathol; 1999 May; 12(5):539-45. PubMed ID: 10349994
[TBL] [Abstract][Full Text] [Related]
12. Microglial activation during epileptogenesis in a mouse model of tuberous sclerosis complex.
Zhang B; Zou J; Han L; Rensing N; Wong M
Epilepsia; 2016 Aug; 57(8):1317-25. PubMed ID: 27263494
[TBL] [Abstract][Full Text] [Related]
13. The specificity and role of microglia in epileptogenesis in mouse models of tuberous sclerosis complex.
Zhang B; Zou J; Han L; Beeler B; Friedman JL; Griffin E; Piao YS; Rensing NR; Wong M
Epilepsia; 2018 Sep; 59(9):1796-1806. PubMed ID: 30079598
[TBL] [Abstract][Full Text] [Related]
14. Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.
Carson RP; Van Nielen DL; Winzenburger PA; Ess KC
Neurobiol Dis; 2012 Jan; 45(1):369-80. PubMed ID: 21907282
[TBL] [Abstract][Full Text] [Related]
15. Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123).
Crowell B; Lee GH; Nikolaeva I; Dal Pozzo V; D'Arcangelo G
eNeuro; 2015; 2(6):. PubMed ID: 26693177
[TBL] [Abstract][Full Text] [Related]
16. Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex.
Feliciano DM; Zhang S; Quon JL; Bordey A
Hum Mol Genet; 2013 May; 22(9):1725-34. PubMed ID: 23349360
[TBL] [Abstract][Full Text] [Related]
17. Antisense suppression of TSC1 gene product, hamartin, enhances neurite outgrowth in NGF-treated PC12h cells.
Floricel F; Higaki K; Maki H; Nanba E; Ninomiya H; Ohno K
Brain Dev; 2007 Sep; 29(8):502-9. PubMed ID: 17376623
[TBL] [Abstract][Full Text] [Related]
18. Tsc1 deficiency-mediated mTOR hyperactivation in vascular endothelial cells causes angiogenesis defects and embryonic lethality.
Ma A; Wang L; Gao Y; Chang Z; Peng H; Zeng N; Gui YS; Tian X; Li X; Cai B; Zhang H; Xu KF
Hum Mol Genet; 2014 Feb; 23(3):693-705. PubMed ID: 24129405
[TBL] [Abstract][Full Text] [Related]
19. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
Zou J; Zhang B; Gutmann DH; Wong M
Epilepsia; 2017 Dec; 58(12):2053-2063. PubMed ID: 29023667
[TBL] [Abstract][Full Text] [Related]
20. Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner.
Astrinidis A; Senapedis W; Henske EP
Hum Mol Genet; 2006 Jan; 15(2):287-97. PubMed ID: 16339216
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
