BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

509 related articles for article (PubMed ID: 26035390)

  • 1. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
    Lenzi J; De Santis R; de Turris V; Morlando M; Laneve P; Calvo A; Caliendo V; Chiò A; Rosa A; Bozzoni I
    Dis Model Mech; 2015 Jul; 8(7):755-66. PubMed ID: 26035390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
    Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
    Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
    Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
    Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.
    Ichiyanagi N; Fujimori K; Yano M; Ishihara-Fujisaki C; Sone T; Akiyama T; Okada Y; Akamatsu W; Matsumoto T; Ishikawa M; Nishimoto Y; Ishihara Y; Sakuma T; Yamamoto T; Tsuiji H; Suzuki N; Warita H; Aoki M; Okano H
    Stem Cell Reports; 2016 Apr; 6(4):496-510. PubMed ID: 26997647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.
    Vance C; Scotter EL; Nishimura AL; Troakes C; Mitchell JC; Kathe C; Urwin H; Manser C; Miller CC; Hortobágyi T; Dragunow M; Rogelj B; Shaw CE
    Hum Mol Genet; 2013 Jul; 22(13):2676-88. PubMed ID: 23474818
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
    Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
    Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ALS-Related Mutant FUS Protein Is Mislocalized to Cytoplasm and Is Recruited into Stress Granules of Fibroblasts from Asymptomatic FUS P525L Mutation Carriers.
    Lo Bello M; Di Fini F; Notaro A; Spataro R; Conforti FL; La Bella V
    Neurodegener Dis; 2017; 17(6):292-303. PubMed ID: 29035885
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
    Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR
    PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
    Marrone L; Poser I; Casci I; Japtok J; Reinhardt P; Janosch A; Andree C; Lee HO; Moebius C; Koerner E; Reinhardt L; Cicardi ME; Hackmann K; Klink B; Poletti A; Alberti S; Bickle M; Hermann A; Pandey UB; Hyman AA; Sterneckert JL
    Stem Cell Reports; 2018 Feb; 10(2):375-389. PubMed ID: 29358088
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
    Daigle JG; Krishnamurthy K; Ramesh N; Casci I; Monaghan J; McAvoy K; Godfrey EW; Daniel DC; Johnson EM; Monahan Z; Shewmaker F; Pasinelli P; Pandey UB
    Acta Neuropathol; 2016 Apr; 131(4):605-20. PubMed ID: 26728149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pericytes Extend Survival of ALS SOD1 Mice and Induce the Expression of Antioxidant Enzymes in the Murine Model and in IPSCs Derived Neuronal Cells from an ALS Patient.
    Coatti GC; Frangini M; Valadares MC; Gomes JP; Lima NO; Cavaçana N; Assoni AF; Pelatti MV; Birbrair A; de Lima ACP; Singer JM; Rocha FMM; Da Silva GL; Mantovani MS; Macedo-Souza LI; Ferrari MFR; Zatz M
    Stem Cell Rev Rep; 2017 Oct; 13(5):686-698. PubMed ID: 28710685
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
    Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
    Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis.
    Shelkovnikova TA; An H; Skelt L; Tregoning JS; Humphreys IR; Buchman VL
    Cell Rep; 2019 Dec; 29(13):4496-4508.e4. PubMed ID: 31875556
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
    Luisier R; Tyzack GE; Hall CE; Mitchell JS; Devine H; Taha DM; Malik B; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
    Nat Commun; 2018 May; 9(1):2010. PubMed ID: 29789581
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo stress granule misprocessing evidenced in a FUS knock-in ALS mouse model.
    Zhang X; Wang F; Hu Y; Chen R; Meng D; Guo L; Lv H; Guan J; Jia Y
    Brain; 2020 May; 143(5):1350-1367. PubMed ID: 32358598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
    Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
    Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
    Naumann M; Pal A; Goswami A; Lojewski X; Japtok J; Vehlow A; Naujock M; Günther R; Jin M; Stanslowsky N; Reinhardt P; Sterneckert J; Frickenhaus M; Pan-Montojo F; Storkebaum E; Poser I; Freischmidt A; Weishaupt JH; Holzmann K; Troost D; Ludolph AC; Boeckers TM; Liebau S; Petri S; Cordes N; Hyman AA; Wegner F; Grill SW; Weis J; Storch A; Hermann A
    Nat Commun; 2018 Jan; 9(1):335. PubMed ID: 29362359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
    Ryu HH; Jun MH; Min KJ; Jang DJ; Lee YS; Kim HK; Lee JA
    Neurobiol Aging; 2014 Dec; 35(12):2822-2831. PubMed ID: 25216585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.
    De Santis R; Alfano V; de Turris V; Colantoni A; Santini L; Garone MG; Antonacci G; Peruzzi G; Sudria-Lopez E; Wyler E; Anink JJ; Aronica E; Landthaler M; Pasterkamp RJ; Bozzoni I; Rosa A
    Cell Rep; 2019 Jun; 27(13):3818-3831.e5. PubMed ID: 31242416
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.
    Farg MA; Soo KY; Warraich ST; Sundaramoorthy V; Blair IP; Atkin JD
    Hum Mol Genet; 2013 Feb; 22(4):717-28. PubMed ID: 23172909
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.