BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 26039994)

  • 1. Human ortholog of Drosophila Melted impedes SMAD2 release from TGF-β receptor I to inhibit TGF-β signaling.
    Shathasivam P; Kollara A; Ringuette MJ; Virtanen C; Wrana JL; Brown TJ
    Proc Natl Acad Sci U S A; 2015 Jun; 112(23):E3000-9. PubMed ID: 26039994
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ventricular Zone Expressed PH Domain Containing 1 (VEPH1): an adaptor protein capable of modulating multiple signaling transduction pathways during normal and pathological development.
    Brown TJ; Kollara A; Shathasivam P; Ringuette MJ
    Cell Commun Signal; 2019 Sep; 17(1):116. PubMed ID: 31500637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transforming growth factor beta signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition.
    Parekh TV; Gama P; Wen X; Demopoulos R; Munger JS; Carcangiu ML; Reiss M; Gold LI
    Cancer Res; 2002 May; 62(10):2778-90. PubMed ID: 12019154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The oncoprotein c-ski functions as a direct antagonist of the transforming growth factor-{beta} type I receptor.
    Ferrand N; Atfi A; Prunier C
    Cancer Res; 2010 Nov; 70(21):8457-66. PubMed ID: 20959473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming growth factor-β stimulates human ovarian cancer cell migration by up-regulating connexin43 expression via Smad2/3 signaling.
    Qiu X; Cheng JC; Zhao J; Chang HM; Leung PC
    Cell Signal; 2015 Oct; 27(10):1956-62. PubMed ID: 26186970
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer.
    Yamamura S; Matsumura N; Mandai M; Huang Z; Oura T; Baba T; Hamanishi J; Yamaguchi K; Kang HS; Okamoto T; Abiko K; Mori S; Murphy SK; Konishi I
    Int J Cancer; 2012 Jan; 130(1):20-8. PubMed ID: 21503873
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells.
    Schedlich LJ; Yenson VM; Baxter RC
    Mol Cell Endocrinol; 2013 Sep; 377(1-2):56-64. PubMed ID: 23831640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2.
    Hayes S; Chawla A; Corvera S
    J Cell Biol; 2002 Sep; 158(7):1239-49. PubMed ID: 12356868
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased androgen receptor levels and signaling in ovarian cancer cells by VEPH1 associated with suppression of SMAD3 and AKT activation.
    Kollara A; Shathasivam P; Park S; Ringuette MJ; Brown TJ
    J Steroid Biochem Mol Biol; 2020 Feb; 196():105498. PubMed ID: 31614206
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization.
    Hwangbo C; Tae N; Lee S; Kim O; Park OK; Kim J; Kwon SH; Lee JH
    Oncogene; 2016 Jan; 35(3):389-401. PubMed ID: 25893292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TrkC binds to the type II TGF-beta receptor to suppress TGF-beta signaling.
    Jin W; Yun C; Kwak MK; Kim TA; Kim SJ
    Oncogene; 2007 Dec; 26(55):7684-91. PubMed ID: 17546043
    [TBL] [Abstract][Full Text] [Related]  

  • 14. VEPH1 expression decreases vascularisation in ovarian cancer xenografts and inhibits VEGFA and IL8 expression through inhibition of AKT activation.
    Shathasivam P; Kollara A; Spybey T; Park S; Clarke B; Ringuette MJ; Brown TJ
    Br J Cancer; 2017 Apr; 116(8):1065-1076. PubMed ID: 28301874
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation.
    Kamato D; Burch ML; Piva TJ; Rezaei HB; Rostam MA; Xu S; Zheng W; Little PJ; Osman N
    Cell Signal; 2013 Oct; 25(10):2017-24. PubMed ID: 23770288
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear translocation of type I transforming growth factor β receptor confers a novel function in RNA processing.
    Chandra M; Zang S; Li H; Zimmerman LJ; Champer J; Tsuyada A; Chow A; Zhou W; Yu Y; Gao H; Ren X; Lin RJ; Wang SE
    Mol Cell Biol; 2012 Jun; 32(12):2183-95. PubMed ID: 22473997
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lactoferrin Promotes Osteogenesis through TGF-β Receptor II Binding in Osteoblasts and Activation of Canonical TGF-β Signaling in MC3T3-E1 Cells and C57BL/6J Mice.
    Li Y; Wang J; Ren F; Zhang W; Zhang H; Zhao L; Zhang M; Cui W; Wang X; Guo H
    J Nutr; 2018 Aug; 148(8):1285-1292. PubMed ID: 29931165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors.
    Khalil AM; Dotimas H; Kahn J; Lamerdin JE; Hayes DB; Gupta P; Franti M
    J Pharmacol Exp Ther; 2016 Sep; 358(3):423-30. PubMed ID: 27340210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tollip, an intracellular trafficking protein, is a novel modulator of the transforming growth factor-β signaling pathway.
    Zhu L; Wang L; Luo X; Zhang Y; Ding Q; Jiang X; Wang X; Pan Y; Chen Y
    J Biol Chem; 2012 Nov; 287(47):39653-63. PubMed ID: 23027871
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glycoprotein M6B Interacts with TβRI to Activate TGF-β-Smad2/3 Signaling and Promote Smooth Muscle Cell Differentiation.
    Zhang X; Xie H; Chang P; Zhao H; Xia Y; Zhang L; Guo X; Huang C; Yan F; Hu L; Lin C; Li Y; Xiong Z; Wang X; Li G; Deng L; Wang S; Tao L
    Stem Cells; 2019 Feb; 37(2):190-201. PubMed ID: 30372567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.