265 related articles for article (PubMed ID: 26043892)
1. GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.
Li Q; Leija C; Rijo-Ferreira F; Chen J; Cestari I; Stuart K; Tu BP; Phillips MA
Mol Microbiol; 2015 Sep; 97(5):1006-20. PubMed ID: 26043892
[TBL] [Abstract][Full Text] [Related]
2. Crystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP.
Terán D; Doleželová E; Keough DT; Hocková D; Zíková A; Guddat LW
FEBS J; 2019 Dec; 286(23):4721-4736. PubMed ID: 31287615
[TBL] [Abstract][Full Text] [Related]
3. Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness.
Steeves CH; Bearne SL
Bioorg Med Chem Lett; 2011 Sep; 21(18):5188-90. PubMed ID: 21840216
[TBL] [Abstract][Full Text] [Related]
4. Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness.
Hofer A; Steverding D; Chabes A; Brun R; Thelander L
Proc Natl Acad Sci U S A; 2001 May; 98(11):6412-6. PubMed ID: 11353848
[TBL] [Abstract][Full Text] [Related]
5. Molecular and biochemical studies on the hypoxanthine-guanine phosphoribosyltransferases of the pathogenic haemoflagellates.
Ullman B; Carter D
Int J Parasitol; 1997 Feb; 27(2):203-13. PubMed ID: 9088991
[TBL] [Abstract][Full Text] [Related]
6. Novel Characteristics of Trypanosoma brucei Guanosine 5'-monophosphate Reductase Distinct from Host Animals.
Bessho T; Okada T; Kimura C; Shinohara T; Tomiyama A; Imamura A; Kuwamura M; Nishimura K; Fujimori K; Shuto S; Ishibashi O; Kubata BK; Inui T
PLoS Negl Trop Dis; 2016 Jan; 10(1):e0004339. PubMed ID: 26731263
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.
Wang Q; Guan YF; Hancock SE; Wahi K; van Geldermalsen M; Zhang BK; Pang A; Nagarajah R; Mak B; Freidman N; Horvath LG; Turner N; Holst J
J Pathol; 2021 Jun; 254(2):135-146. PubMed ID: 33768538
[TBL] [Abstract][Full Text] [Related]
8. Hypoxanthine-Guanine Phosphoribosyltransferase Is Dispensable for Mycobacterium smegmatis Viability.
Knejzlík Z; Herkommerová K; Hocková D; Pichová I
J Bacteriol; 2020 Feb; 202(5):. PubMed ID: 31818925
[TBL] [Abstract][Full Text] [Related]
9. Purine metabolism in the bloodstream forms of Trypanosoma gambiense and Trypanosoma rhodesiense.
Fish WR; Looker DL; Marr JJ; Berens RL
Biochim Biophys Acta; 1982 Nov; 719(2):223-31. PubMed ID: 6817814
[TBL] [Abstract][Full Text] [Related]
10. Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active.
Glockzin K; Meek TD; Katzfuss A
PLoS Negl Trop Dis; 2022 Feb; 16(2):e0009926. PubMed ID: 35104286
[TBL] [Abstract][Full Text] [Related]
11. Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei.
Vodnala M; Fijolek A; Rofougaran R; Mosimann M; Mäser P; Hofer A
J Biol Chem; 2008 Feb; 283(9):5380-8. PubMed ID: 18167353
[TBL] [Abstract][Full Text] [Related]
12. Pyrimidine Salvage Enzymes Are Essential for De Novo Biosynthesis of Deoxypyrimidine Nucleotides in Trypanosoma brucei.
Leija C; Rijo-Ferreira F; Kinch LN; Grishin NV; Nischan N; Kohler JJ; Hu Z; Phillips MA
PLoS Pathog; 2016 Nov; 12(11):e1006010. PubMed ID: 27820863
[TBL] [Abstract][Full Text] [Related]
13. Identification and characterization of guanosine 5'-monophosphate reductase of Trypanosoma congolense as a drug target.
Sarwono AEY; Suganuma K; Mitsuhashi S; Okada T; Musinguzi SP; Shigetomi K; Inoue N; Ubukata M
Parasitol Int; 2017 Oct; 66(5):537-544. PubMed ID: 28366788
[TBL] [Abstract][Full Text] [Related]
14. A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.
Boitz JM; Ullman B
J Biol Chem; 2006 Jun; 281(23):16084-9. PubMed ID: 16603734
[TBL] [Abstract][Full Text] [Related]
15. Crystal structures and inhibition of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase.
Terán D; Hocková D; Česnek M; Zíková A; Naesens L; Keough DT; Guddat LW
Sci Rep; 2016 Oct; 6():35894. PubMed ID: 27786284
[TBL] [Abstract][Full Text] [Related]
16. Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma brucei.
Allen TE; Ullman B
Nucleic Acids Res; 1993 Nov; 21(23):5431-8. PubMed ID: 8265360
[TBL] [Abstract][Full Text] [Related]
17. Kinetic Characterization and Inhibition of
Glockzin K; Kostomiris D; Minnow YVT; Suthagar K; Clinch K; Gai S; Buckler JN; Schramm VL; Tyler PC; Meek TD; Katzfuss A
Biochemistry; 2022 Oct; 61(19):2088-2105. PubMed ID: 36193631
[TBL] [Abstract][Full Text] [Related]
18. Clinical severity in Lesch-Nyhan disease: the role of residual enzyme and compensatory pathways.
Fu R; Sutcliffe D; Zhao H; Huang X; Schretlen DJ; Benkovic S; Jinnah HA
Mol Genet Metab; 2015 Jan; 114(1):55-61. PubMed ID: 25481104
[TBL] [Abstract][Full Text] [Related]
19. The enzymes of purine salvage in Trypanosoma cruzi, Trypanosoma brucei and Leishmania mexicana.
Davies MJ; Ross AM; Gutteridge WE
Parasitology; 1983 Oct; 87 (Pt 2)():211-7. PubMed ID: 6316234
[TBL] [Abstract][Full Text] [Related]
20. De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo.
Kofoed EM; Yan D; Katakam AK; Reichelt M; Lin B; Kim J; Park S; Date SV; Monk IR; Xu M; Austin CD; Maurer T; Tan MW
J Bacteriol; 2016 Jul; 198(14):2001-2015. PubMed ID: 27161118
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
