BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 26045618)

  • 1. Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion.
    Yu C; Huo X; Agoston AT; Zhang X; Theiss AL; Cheng E; Zhang Q; Zaika A; Pham TH; Wang DH; Lobie PE; Odze RD; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2015 Aug; 309(3):G146-61. PubMed ID: 26045618
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells.
    Zhang HY; Zhang Q; Zhang X; Yu C; Huo X; Cheng E; Wang DH; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2011 Mar; 300(3):G454-60. PubMed ID: 21148399
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Malignant transformation of non-neoplastic Barrett's epithelial cells through well-defined genetic manipulations.
    Zhang X; Yu C; Wilson K; Zhang HY; Melton SD; Huo X; Wang DH; Genta RM; Spechler SJ; Souza RF
    PLoS One; 2010 Sep; 5(9):. PubMed ID: 20927195
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.
    Yu C; Zhang Q; Zhang HY; Zhang X; Huo X; Cheng E; Wang DH; Arbiser JL; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2012 Sep; 303(5):G561-9. PubMed ID: 22744336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of telomerase-immortalized, non-neoplastic, human Barrett's cell line (BAR-T).
    Jaiswal KR; Morales CP; Feagins LA; Gandia KG; Zhang X; Zhang HY; Hormi-Carver K; Shen Y; Elder F; Ramirez RD; Sarosi GA; Spechler SJ; Souza RF
    Dis Esophagus; 2007; 20(3):256-64. PubMed ID: 17509124
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In Barrett's epithelial cells, weakly acidic bile salt solutions cause oxidative DNA damage with response and repair mediated by p38.
    Huo X; Dunbar KB; Zhang X; Zhang Q; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2020 Mar; 318(3):G464-G478. PubMed ID: 31984785
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation.
    Gough DJ; Koetz L; Levy DE
    PLoS One; 2013; 8(11):e83395. PubMed ID: 24312439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Immunohistological study of cell cycle-related factors, oncogene expression, and cell proliferation in adenocarcinoma developed in Barrett's esophagus.
    Fujii T; Nakagawa S; Hanzawa M; Sueyoshi S; Fujita H; Shirouzu K; Yamana H
    Oncol Rep; 2003; 10(2):427-31. PubMed ID: 12579284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids.
    Peng S; Huo X; Rezaei D; Zhang Q; Zhang X; Yu C; Asanuma K; Cheng E; Pham TH; Wang DH; Chen M; Souza RF; Spechler SJ
    Am J Physiol Gastrointest Liver Physiol; 2014 Jul; 307(2):G129-39. PubMed ID: 24852569
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In benign Barrett's epithelial cells, acid exposure generates reactive oxygen species that cause DNA double-strand breaks.
    Zhang HY; Hormi-Carver K; Zhang X; Spechler SJ; Souza RF
    Cancer Res; 2009 Dec; 69(23):9083-9. PubMed ID: 19920191
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differences in activity and phosphorylation of MAPK enzymes in esophageal squamous cells of GERD patients with and without Barrett's esophagus.
    Zhang HY; Zhang X; Chen X; Thomas D; Hormi-Carver K; Elder F; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2008 Sep; 295(3):G470-8. PubMed ID: 18617556
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toll-like Receptor 2 Signalling and the Lysosomal Machinery in Barrett's Esophagus.
    Verbeek RE; Siersema PD; Vleggaar FP; Ten Kate FJ; Posthuma G; Souza RF; de Haan J; van Baal JW
    J Gastrointestin Liver Dis; 2016 Sep; 25(3):273-82. PubMed ID: 27689189
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation.
    Leslie K; Gao SP; Berishaj M; Podsypanina K; Ho H; Ivashkiv L; Bromberg J
    Breast Cancer Res; 2010; 12(5):R80. PubMed ID: 20929542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of the p53 homologue p63alpha and DeltaNp63alpha in the neoplastic sequence of Barrett's oesophagus: correlation with morphology and p53 protein.
    Hall PA; Woodman AC; Campbell SJ; Shepherd NA
    Gut; 2001 Nov; 49(5):618-23. PubMed ID: 11600462
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells.
    Huo X; Juergens S; Zhang X; Rezaei D; Yu C; Strauch ED; Wang JY; Cheng E; Meyer F; Wang DH; Zhang Q; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2011 Aug; 301(2):G278-86. PubMed ID: 21636532
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acid has antiproliferative effects in nonneoplastic Barrett's epithelial cells.
    Feagins LA; Zhang HY; Hormi-Carver K; Quinones MH; Thomas D; Zhang X; Terada LS; Spechler SJ; Ramirez RD; Souza RF
    Am J Gastroenterol; 2007 Jan; 102(1):10-20. PubMed ID: 17266684
    [TBL] [Abstract][Full Text] [Related]  

  • 17. STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.
    Timme S; Ihde S; Fichter CD; Waehle V; Bogatyreva L; Atanasov K; Kohler I; Schöpflin A; Geddert H; Faller G; Klimstra D; Tang L; Reinheckel T; Hauschke D; Busch H; Boerries M; Werner M; Lassmann S
    Oncogene; 2014 Jun; 33(25):3256-66. PubMed ID: 23912451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-grade dysplasia and superficial adenocarcinoma in Barrett's esophagus: histological mapping and expression of p53, p21 and Bcl-2 oncoproteins.
    Chatelain D; Fléjou JF
    Virchows Arch; 2003 Jan; 442(1):18-24. PubMed ID: 12536310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Origin of adenocarcinoma in Barrett's esophagus: p53 and Ki67 expression and histopathologic background.
    Szachnowicz S; Cecconello I; Iriya K; Marson AG; Takeda FR; Gama-Rodrigues JJ
    Clinics (Sao Paulo); 2005 Apr; 60(2):103-12. PubMed ID: 15880245
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.
    Gough DJ; Corlett A; Schlessinger K; Wegrzyn J; Larner AC; Levy DE
    Science; 2009 Jun; 324(5935):1713-6. PubMed ID: 19556508
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.