These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The NIH Molecular Libraries Program: identifying chemical probes for new medicines. McCarthy A Chem Biol; 2010 Jun; 17(6):549-50. PubMed ID: 20609403 [No Abstract] [Full Text] [Related]
3. A crowdsourcing evaluation of the NIH chemical probes. Oprea TI; Bologa CG; Boyer S; Curpan RF; Glen RC; Hopkins AL; Lipinski CA; Marshall GR; Martin YC; Ostopovici-Halip L; Rishton G; Ursu O; Vaz RJ; Waller C; Waldmann H; Sklar LA Nat Chem Biol; 2009 Jul; 5(7):441-7. PubMed ID: 19536101 [TBL] [Abstract][Full Text] [Related]
4. National Institutes of Health. Drug-screening program looking for a home. Kaiser J Science; 2011 Oct; 334(6054):299. PubMed ID: 22021828 [No Abstract] [Full Text] [Related]
5. Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor. Conley JM; Brand CS; Bogard AS; Pratt EP; Xu R; Hockerman GH; Ostrom RS; Dessauer CW; Watts VJ J Pharmacol Exp Ther; 2013 Nov; 347(2):276-87. PubMed ID: 24008337 [TBL] [Abstract][Full Text] [Related]
7. Addressing Compound Reactivity and Aggregation Assay Interferences: Case Studies of Biochemical High-Throughput Screening Campaigns Benefiting from the National Institutes of Health Coussens NP; Auld DS; Thielman JR; Wagner BK; Dahlin JL SLAS Discov; 2021 Dec; 26(10):1280-1290. PubMed ID: 34218710 [TBL] [Abstract][Full Text] [Related]
8. PubChem as a public resource for drug discovery. Li Q; Cheng T; Wang Y; Bryant SH Drug Discov Today; 2010 Dec; 15(23-24):1052-7. PubMed ID: 20970519 [TBL] [Abstract][Full Text] [Related]
9. NIH launches open science Alzheimer initiative. Mullard A Nat Rev Drug Discov; 2019 Nov; 18(12):895. PubMed ID: 31780852 [No Abstract] [Full Text] [Related]
10. Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs. Coussens NP; Braisted JC; Peryea T; Sittampalam GS; Simeonov A; Hall MD Pharmacol Rev; 2017 Oct; 69(4):479-496. PubMed ID: 28931623 [TBL] [Abstract][Full Text] [Related]
11. Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP. van Adrichem AJ; Fagerholm A; Turunen L; Lehto A; Saarela J; Koskinen A; Repasky GA; Wennerberg K Comb Chem High Throughput Screen; 2015; 18(1):3-17. PubMed ID: 25479424 [TBL] [Abstract][Full Text] [Related]
12. Small molecule screening in zebrafish. Peal DS; Peterson RT; Milan D J Cardiovasc Transl Res; 2010 Oct; 3(5):454-60. PubMed ID: 20680709 [TBL] [Abstract][Full Text] [Related]
13. Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors. Lukens AK; Heidebrecht RW; Mulrooney C; Beaudoin JA; Comer E; Duvall JR; Fitzgerald ME; Masi D; Galinsky K; Scherer CA; Palmer M; Munoz B; Foley M; Schreiber SL; Wiegand RC; Wirth DF J Infect Dis; 2015 Apr; 211(7):1097-103. PubMed ID: 25336726 [TBL] [Abstract][Full Text] [Related]
14. High-throughput discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry. Tan LP; Wu H; Yang PY; Kalesh KA; Zhang X; Hu M; Srinivasan R; Yao SQ Org Lett; 2009 Nov; 11(22):5102-5. PubMed ID: 19852491 [TBL] [Abstract][Full Text] [Related]
15. Small-molecule inhibitors of lysine methyltransferases SMYD2 and SMYD3: current trends. Fabini E; Manoni E; Ferroni C; Rio AD; Bartolini M Future Med Chem; 2019 Apr; 11(8):901-921. PubMed ID: 30998113 [TBL] [Abstract][Full Text] [Related]
16. Small molecule probes for cellular death machines. Li Y; Qian L; Yuan J Curr Opin Chem Biol; 2017 Aug; 39():74-82. PubMed ID: 28628894 [TBL] [Abstract][Full Text] [Related]
17. Epigenetic small molecule modulators of histone and DNA methylation. Hauser AT; Robaa D; Jung M Curr Opin Chem Biol; 2018 Aug; 45():73-85. PubMed ID: 29579619 [TBL] [Abstract][Full Text] [Related]
18. Evaluating and evolving a screening library in academia: the St Jude approach. Nishiguchi G; Das S; Ochoada J; Long H; Lee RE; Rankovic Z; Shelat AA Drug Discov Today; 2021 Apr; 26(4):1060-1069. PubMed ID: 33453364 [TBL] [Abstract][Full Text] [Related]
19. Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective. Bauer RA; Wurst JM; Tan DS Curr Opin Chem Biol; 2010 Jun; 14(3):308-14. PubMed ID: 20202892 [TBL] [Abstract][Full Text] [Related]
20. The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway. De Cesare V; Johnson C; Barlow V; Hastie J; Knebel A; Trost M Cell Chem Biol; 2018 Sep; 25(9):1117-1127.e4. PubMed ID: 30017913 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]