212 related articles for article (PubMed ID: 26046462)
1. The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.
Suijker J; Baelde HJ; Roelofs H; Cleton-Jansen AM; Bovée JV
Oncotarget; 2015 Jun; 6(17):14832-42. PubMed ID: 26046462
[TBL] [Abstract][Full Text] [Related]
2. The oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation.
Liu L; Hu K; Feng J; Wang H; Fu S; Wang B; Wang L; Xu Y; Yu X; Huang H
BMC Cancer; 2021 Jan; 21(1):36. PubMed ID: 33413208
[TBL] [Abstract][Full Text] [Related]
3. IDH1 immunohistochemistry reactivity and mosaic IDH1 or IDH2 somatic mutations in pediatric sporadic enchondroma and enchondromatosis.
Saiji E; Pause FG; Lascombes P; Cerato Biderbost C; Marq NL; Berczy M; Merlini L; Rougemont AL
Virchows Arch; 2019 Nov; 475(5):625-636. PubMed ID: 31240473
[TBL] [Abstract][Full Text] [Related]
4. Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.
Jin Y; Elalaf H; Watanabe M; Tamaki S; Hineno S; Matsunaga K; Woltjen K; Kobayashi Y; Nagata S; Ikeya M; Kato T; Okamoto T; Matsuda S; Toguchida J
PLoS One; 2015; 10(7):e0131998. PubMed ID: 26161668
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines.
Suijker J; Oosting J; Koornneef A; Struys EA; Salomons GS; Schaap FG; Waaijer CJ; Wijers-Koster PM; Briaire-de Bruijn IH; Haazen L; Riester SM; Dudakovic A; Danen E; Cleton-Jansen AM; van Wijnen AJ; Bovée JV
Oncotarget; 2015 May; 6(14):12505-19. PubMed ID: 25895133
[TBL] [Abstract][Full Text] [Related]
6. IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours.
Amary MF; Bacsi K; Maggiani F; Damato S; Halai D; Berisha F; Pollock R; O'Donnell P; Grigoriadis A; Diss T; Eskandarpour M; Presneau N; Hogendoorn PC; Futreal A; Tirabosco R; Flanagan AM
J Pathol; 2011 Jul; 224(3):334-43. PubMed ID: 21598255
[TBL] [Abstract][Full Text] [Related]
7. The role of BMP-7 in chondrogenic and osteogenic differentiation of human bone marrow multipotent mesenchymal stromal cells in vitro.
Shen B; Wei A; Whittaker S; Williams LA; Tao H; Ma DD; Diwan AD
J Cell Biochem; 2010 Feb; 109(2):406-16. PubMed ID: 19950204
[TBL] [Abstract][Full Text] [Related]
8. Conditioned Medium Enhances Osteogenic Differentiation of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells.
Zhong S; He X; Li Y; Lou X
Tissue Eng Regen Med; 2019 Apr; 16(2):141-150. PubMed ID: 30989041
[TBL] [Abstract][Full Text] [Related]
9. Characterisation of isocitrate dehydrogenase 1/isocitrate dehydrogenase 2 gene mutation and the d-2-hydroxyglutarate oncometabolite level in dedifferentiated chondrosarcoma.
Mohammad N; Wong D; Lum A; Lin J; Ho J; Lee CH; Yip S
Histopathology; 2020 Apr; 76(5):722-730. PubMed ID: 31609487
[TBL] [Abstract][Full Text] [Related]
10. Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy.
Pope WB; Prins RM; Albert Thomas M; Nagarajan R; Yen KE; Bittinger MA; Salamon N; Chou AP; Yong WH; Soto H; Wilson N; Driggers E; Jang HG; Su SM; Schenkein DP; Lai A; Cloughesy TF; Kornblum HI; Wu H; Fantin VR; Liau LM
J Neurooncol; 2012 Mar; 107(1):197-205. PubMed ID: 22015945
[TBL] [Abstract][Full Text] [Related]
11. Chondrogenic differentiation of human mesenchymal stem cells in micro-masses is impaired by high doses of the chemokine CXCL7.
Kalwitz G; Neumann K; Ringe J; Sezer O; Sittinger M; Endres M; Kaps C
J Tissue Eng Regen Med; 2011 Jan; 5(1):50-9. PubMed ID: 20652876
[TBL] [Abstract][Full Text] [Related]
12. 2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation.
Schvartzman JM; Reuter VP; Koche RP; Thompson CB
Proc Natl Acad Sci U S A; 2019 Jun; 116(26):12851-12856. PubMed ID: 31182575
[TBL] [Abstract][Full Text] [Related]
13. Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche.
Birmingham E; Niebur GL; McHugh PE; Shaw G; Barry FP; McNamara LM
Eur Cell Mater; 2012 Jan; 23():13-27. PubMed ID: 22241610
[TBL] [Abstract][Full Text] [Related]
14. Myocilin stimulates osteogenic differentiation of mesenchymal stem cells through mitogen-activated protein kinase signaling.
Kwon HS; Johnson TV; Tomarev SI
J Biol Chem; 2013 Jun; 288(23):16882-16894. PubMed ID: 23629661
[TBL] [Abstract][Full Text] [Related]
15. In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors.
Salamanca-Cardona L; Shah H; Poot AJ; Correa FM; Di Gialleonardo V; Lui H; Miloushev VZ; Granlund KL; Tee SS; Cross JR; Thompson CB; Keshari KR
Cell Metab; 2017 Dec; 26(6):830-841.e3. PubMed ID: 29056515
[TBL] [Abstract][Full Text] [Related]
16. NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man.
Pountos I; Giannoudis PV; Jones E; English A; Churchman S; Field S; Ponchel F; Bird H; Emery P; McGonagle D
J Cell Mol Med; 2011 Mar; 15(3):525-34. PubMed ID: 20070439
[TBL] [Abstract][Full Text] [Related]
17. Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations.
Berger RS; Ellmann L; Reinders J; Kreutz M; Stempfl T; Oefner PJ; Dettmer K
Sci Rep; 2019 May; 9(1):7436. PubMed ID: 31092874
[TBL] [Abstract][Full Text] [Related]
18. Isocitrate dehydrogenase gene mutations and 2-hydroxyglutarate accumulation in esophageal squamous cell carcinoma.
Miyake K; Baba Y; Ishimoto T; Hiyoshi Y; Iwatsuki M; Miyamoto Y; Yoshida N; Watanabe M; Ogata Y; Nagayama M; Silsirivanit A; Kobayashi D; Araki N; Baba H
Med Oncol; 2018 Nov; 36(1):11. PubMed ID: 30506321
[TBL] [Abstract][Full Text] [Related]
19. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Pansuriya TC; van Eijk R; d'Adamo P; van Ruler MA; Kuijjer ML; Oosting J; Cleton-Jansen AM; van Oosterwijk JG; Verbeke SL; Meijer D; van Wezel T; Nord KH; Sangiorgi L; Toker B; Liegl-Atzwanger B; San-Julian M; Sciot R; Limaye N; Kindblom LG; Daugaard S; Godfraind C; Boon LM; Vikkula M; Kurek KC; Szuhai K; French PJ; Bovée JV
Nat Genet; 2011 Nov; 43(12):1256-61. PubMed ID: 22057234
[TBL] [Abstract][Full Text] [Related]
20. Induction of sarcomas by mutant IDH2.
Lu C; Venneti S; Akalin A; Fang F; Ward PS; Dematteo RG; Intlekofer AM; Chen C; Ye J; Hameed M; Nafa K; Agaram NP; Cross JR; Khanin R; Mason CE; Healey JH; Lowe SW; Schwartz GK; Melnick A; Thompson CB
Genes Dev; 2013 Sep; 27(18):1986-98. PubMed ID: 24065766
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]