These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 26046644)

  • 1. Rag Ubiquitination Recruits a GATOR1: Attenuation of Amino Acid-Induced mTORC1 Signaling.
    Fingar DC
    Mol Cell; 2015 Jun; 58(5):713-5. PubMed ID: 26046644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.
    Deng L; Jiang C; Chen L; Jin J; Wei J; Zhao L; Chen M; Pan W; Xu Y; Chu H; Wang X; Ge X; Li D; Liao L; Liu M; Li L; Wang P
    Mol Cell; 2015 Jun; 58(5):804-18. PubMed ID: 25936802
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
    Jin G; Lee SW; Zhang X; Cai Z; Gao Y; Chou PC; Rezaeian AH; Han F; Wang CY; Yao JC; Gong Z; Chan CH; Huang CY; Tsai FJ; Tsai CH; Tu SH; Wu CH; Sarbassov dos D; Ho YS; Lin HK
    Mol Cell; 2015 Jun; 58(6):989-1000. PubMed ID: 26051179
    [TBL] [Abstract][Full Text] [Related]  

  • 4. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
    Wolfson RL; Chantranupong L; Wyant GA; Gu X; Orozco JM; Shen K; Condon KJ; Petri S; Kedir J; Scaria SM; Abu-Remaileh M; Frankel WN; Sabatini DM
    Nature; 2017 Mar; 543(7645):438-442. PubMed ID: 28199306
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SZT2 dictates GATOR control of mTORC1 signalling.
    Peng M; Yin N; Li MO
    Nature; 2017 Mar; 543(7645):433-437. PubMed ID: 28199315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
    Shen K; Huang RK; Brignole EJ; Condon KJ; Valenstein ML; Chantranupong L; Bomaliyamu A; Choe A; Hong C; Yu Z; Sabatini DM
    Nature; 2018 Apr; 556(7699):64-69. PubMed ID: 29590090
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
    Bar-Peled L; Chantranupong L; Cherniack AD; Chen WW; Ottina KA; Grabiner BC; Spear ED; Carter SL; Meyerson M; Sabatini DM
    Science; 2013 May; 340(6136):1100-6. PubMed ID: 23723238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
    Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
    Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.
    Kwak SS; Kang KH; Kim S; Lee S; Lee JH; Kim JW; Byun B; Meadows GG; Joe CO
    Cell Signal; 2016 Feb; 28(2):32-41. PubMed ID: 26582740
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rag GTPase in amino acid signaling.
    Kim J; Kim E
    Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.
    Peng M; Yin N; Li MO
    Cell; 2014 Sep; 159(1):122-133. PubMed ID: 25259925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rag GTPases are cardioprotective by regulating lysosomal function.
    Kim YC; Park HW; Sciarretta S; Mo JS; Jewell JL; Russell RC; Wu X; Sadoshima J; Guan KL
    Nat Commun; 2014 Jul; 5():4241. PubMed ID: 24980141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism. Differential regulation of mTORC1 by leucine and glutamine.
    Jewell JL; Kim YC; Russell RC; Yu FX; Park HW; Plouffe SW; Tagliabracci VS; Guan KL
    Science; 2015 Jan; 347(6218):194-8. PubMed ID: 25567907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
    Shen K; Valenstein ML; Gu X; Sabatini DM
    J Biol Chem; 2019 Feb; 294(8):2970-2975. PubMed ID: 30651352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A multiprotein complex negatively regulates RAG GTPases and mTORC1.
    Cancer Discov; 2013 Jul; 3(7):OF24. PubMed ID: 23847368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
    Wang S; Tsun ZY; Wolfson RL; Shen K; Wyant GA; Plovanich ME; Yuan ED; Jones TD; Chantranupong L; Comb W; Wang T; Bar-Peled L; Zoncu R; Straub C; Kim C; Park J; Sabatini BL; Sabatini DM
    Science; 2015 Jan; 347(6218):188-94. PubMed ID: 25567906
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
    Efeyan A; Zoncu R; Chang S; Gumper I; Snitkin H; Wolfson RL; Kirak O; Sabatini DD; Sabatini DM
    Nature; 2013 Jan; 493(7434):679-83. PubMed ID: 23263183
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
    Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.
    Kim JS; Ro SH; Kim M; Park HW; Semple IA; Park H; Cho US; Wang W; Guan KL; Karin M; Lee JH
    Sci Rep; 2015 Mar; 5():9502. PubMed ID: 25819761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.