BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

832 related articles for article (PubMed ID: 26048156)

  • 1. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
    Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S
    Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy.
    Carbo M; Brandi V; Pascarella G; Staid DS; Colotti G; Polticelli F; Ilari A; Morea V
    Int J Mol Med; 2019 Dec; 44(6):2223-2233. PubMed ID: 31638189
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Huntington's disease is a disorder of the corpus striatum: focus on Rhes (Ras homologue enriched in the striatum).
    Subramaniam S; Snyder SH
    Neuropharmacology; 2011 Jun; 60(7-8):1187-92. PubMed ID: 21044641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of Rhes, Ras homolog enriched in striatum, in neurodegenerative processes.
    Harrison LM; Lahoste GJ
    Exp Cell Res; 2013 Sep; 319(15):2310-5. PubMed ID: 23583659
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Striatal Induction and Spread of the Huntington's Disease Protein: A Novel Rhes Route.
    Subramaniam S
    J Huntingtons Dis; 2022; 11(3):281-290. PubMed ID: 35871361
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative.
    Tebbenkamp AT; Green C; Xu G; Denovan-Wright EM; Rising AC; Fromholt SE; Brown HH; Swing D; Mandel RJ; Tessarollo L; Borchelt DR
    Hum Mol Genet; 2011 Jul; 20(14):2770-82. PubMed ID: 21515588
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Viral vector mediated expression of mutant huntingtin in the dorsal raphe produces disease-related neuropathology but not depressive-like behaviors in wildtype mice.
    Pitzer M; Lueras J; Warden A; Weber S; McBride J
    Brain Res; 2015 May; 1608():177-90. PubMed ID: 25732261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brain.
    Ramírez-Jarquín UN; Sharma M; Shahani N; Li Y; Boregowda S; Subramaniam S
    Sci Adv; 2022 Mar; 8(12):eabm3877. PubMed ID: 35319973
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
    Wang N; Gray M; Lu XH; Cantle JP; Holley SM; Greiner E; Gu X; Shirasaki D; Cepeda C; Li Y; Dong H; Levine MS; Yang XW
    Nat Med; 2014 May; 20(5):536-41. PubMed ID: 24784230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice.
    Wang CE; Li S; Li XJ
    Mol Brain; 2010 Nov; 3():33. PubMed ID: 21044321
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease.
    Ebert AD; Barber AE; Heins BM; Svendsen CN
    Exp Neurol; 2010 Jul; 224(1):155-62. PubMed ID: 20227407
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
    Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
    Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rhes depletion promotes striatal accumulation and aggregation of mutant huntingtin in a presymptomatic HD mouse model.
    Pan Y; Tang B; Li XJ; Li S; Liu Q
    Front Aging Neurosci; 2023; 15():1237018. PubMed ID: 37637962
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.
    Mealer RG; Murray AJ; Shahani N; Subramaniam S; Snyder SH
    J Biol Chem; 2014 Feb; 289(6):3547-54. PubMed ID: 24324270
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Valentine DT; Sapp E; Lu B; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Jun; 5(2):163-74. PubMed ID: 27314618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes.
    Lee JH; Tecedor L; Chen YH; Monteys AM; Sowada MJ; Thompson LM; Davidson BL
    Neuron; 2015 Jan; 85(2):303-15. PubMed ID: 25556834
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model.
    Lu Z; Marks E; Chen J; Moline J; Barrows L; Raisbeck M; Volitakis I; Cherny RA; Chopra V; Bush AI; Hersch S; Fox JH
    Neurobiol Dis; 2014 Nov; 71():34-42. PubMed ID: 25014023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
    Yu ZX; Li SH; Evans J; Pillarisetti A; Li H; Li XJ
    J Neurosci; 2003 Mar; 23(6):2193-202. PubMed ID: 12657678
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Attenuation of Rhes activity significantly delays the appearance of behavioral symptoms in a mouse model of Huntington's disease.
    Baiamonte BA; Lee FA; Brewer ST; Spano D; LaHoste GJ
    PLoS One; 2013; 8(1):e53606. PubMed ID: 23349722
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.
    Damiano M; Diguet E; Malgorn C; D'Aurelio M; Galvan L; Petit F; Benhaim L; Guillermier M; Houitte D; Dufour N; Hantraye P; Canals JM; Alberch J; Delzescaux T; Déglon N; Beal MF; Brouillet E
    Hum Mol Genet; 2013 Oct; 22(19):3869-82. PubMed ID: 23720495
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.