233 related articles for article (PubMed ID: 26048785)
1. Meridianin derivatives as potent Dyrk1A inhibitors and neuroprotective agents.
Yadav RR; Sharma S; Joshi P; Wani A; Vishwakarma RA; Kumar A; Bharate SB
Bioorg Med Chem Lett; 2015 Aug; 25(15):2948-52. PubMed ID: 26048785
[TBL] [Abstract][Full Text] [Related]
2. Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus.
Shaw SJ; Goff DA; Lin N; Singh R; Li W; McLaughlin J; Baltgalvis KA; Payan DG; Kinsella TM
Bioorg Med Chem Lett; 2017 Jun; 27(11):2617-2621. PubMed ID: 28408219
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
Liu W; Liu X; Tian L; Gao Y; Liu W; Chen H; Jiang X; Xu Z; Ding H; Zhao Q
Eur J Med Chem; 2021 Oct; 222():113554. PubMed ID: 34098466
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.
Giraud F; Alves G; Debiton E; Nauton L; Théry V; Durieu E; Ferandin Y; Lozach O; Meijer L; Anizon F; Pereira E; Moreau P
J Med Chem; 2011 Jul; 54(13):4474-89. PubMed ID: 21623630
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors.
Dehbi O; Tikad A; Bourg S; Bonnet P; Lozach O; Meijer L; Aadil M; Akssira M; Guillaumet G; Routier S
Eur J Med Chem; 2014 Jun; 80():352-63. PubMed ID: 24793883
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.
Akue-Gedu R; Debiton E; Ferandin Y; Meijer L; Prudhomme M; Anizon F; Moreau P
Bioorg Med Chem; 2009 Jul; 17(13):4420-4. PubMed ID: 19477650
[TBL] [Abstract][Full Text] [Related]
7. Computational & experimental evaluation of the structure/activity relationship of β-carbolines as DYRK1A inhibitors.
Drung B; Scholz C; Barbosa VA; Nazari A; Sarragiotto MH; Schmidt B
Bioorg Med Chem Lett; 2014 Oct; 24(20):4854-60. PubMed ID: 25240617
[TBL] [Abstract][Full Text] [Related]
8. Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.
AlNajjar YT; Gabr M; ElHady AK; Salah M; Wilms G; Abadi AH; Becker W; Abdel-Halim M; Engel M
Eur J Med Chem; 2022 Jan; 227():113911. PubMed ID: 34710745
[TBL] [Abstract][Full Text] [Related]
9. QSAR and pharmacophore study of Dyrk1A inhibitory meridianin analogs as potential agents for treatment of neurodegenerative diseases.
Bharate SB; Yadav RR; Vishwakarma RA
Med Chem; 2013 Feb; 9(1):152-61. PubMed ID: 22920091
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, antimalarial and antitubercular activities of meridianin derivatives.
Yadav RR; Khan SI; Singh S; Khan IA; Vishwakarma RA; Bharate SB
Eur J Med Chem; 2015 Jun; 98():160-9. PubMed ID: 26005918
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and kinase inhibitory activity of novel substituted indigoids.
Beauchard A; Laborie H; Rouillard H; Lozach O; Ferandin Y; Le Guével R; Guguen-Guillouzo C; Meijer L; Besson T; Thiéry V
Bioorg Med Chem; 2009 Sep; 17(17):6257-63. PubMed ID: 19665384
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors.
Bruel A; Bénéteau R; Chabanne M; Lozach O; Le Guevel R; Ravache M; Bénédetti H; Meijer L; Logé C; Robert JM
Bioorg Med Chem Lett; 2014 Nov; 24(21):5037-40. PubMed ID: 25248682
[TBL] [Abstract][Full Text] [Related]
13. Development of novel 2,4-bispyridyl thiophene-based compounds as highly potent and selective Dyrk1A inhibitors. Part I: Benzamide and benzylamide derivatives.
Darwish SS; Abdel-Halim M; Salah M; Abadi AH; Becker W; Engel M
Eur J Med Chem; 2018 Sep; 157():1031-1050. PubMed ID: 30193214
[TBL] [Abstract][Full Text] [Related]
14. Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors.
Weber C; Sipos M; Paczal A; Balint B; Kun V; Foloppe N; Dokurno P; Massey AJ; Walmsley DL; Hubbard RE; Murray J; Benwell K; Edmonds T; Demarles D; Bruno A; Burbridge M; Cruzalegui F; Kotschy A
J Med Chem; 2021 May; 64(10):6745-6764. PubMed ID: 33975430
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues: a novel DYRK1A inhibitor class.
Neagoie C; Vedrenne E; Buron F; Mérour JY; Rosca S; Bourg S; Lozach O; Meijer L; Baldeyrou B; Lansiaux A; Routier S
Eur J Med Chem; 2012 Mar; 49():379-96. PubMed ID: 22305342
[TBL] [Abstract][Full Text] [Related]
16. Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Tahtouh T; Elkins JM; Filippakopoulos P; Soundararajan M; Burgy G; Durieu E; Cochet C; Schmid RS; Lo DC; Delhommel F; Oberholzer AE; Pearl LH; Carreaux F; Bazureau JP; Knapp S; Meijer L
J Med Chem; 2012 Nov; 55(21):9312-30. PubMed ID: 22998443
[TBL] [Abstract][Full Text] [Related]
17. Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.
Gourdain S; Dairou J; Denhez C; Bui LC; Rodrigues-Lima F; Janel N; Delabar JM; Cariou K; Dodd RH
J Med Chem; 2013 Dec; 56(23):9569-85. PubMed ID: 24188002
[TBL] [Abstract][Full Text] [Related]
18. Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity.
Kumar K; Man-Un Ung P; Wang P; Wang H; Li H; Andrews MK; Stewart AF; Schlessinger A; DeVita RJ
Eur J Med Chem; 2018 Sep; 157():1005-1016. PubMed ID: 30170319
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors.
Schmitt C; Kail D; Mariano M; Empting M; Weber N; Paul T; Hartmann RW; Engel M
PLoS One; 2014; 9(3):e87851. PubMed ID: 24676346
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and Cytotoxicity Evaluation of Novel Indole Derivatives as Potential Anti-Cancer Agents.
Kamel MM; Abdel-Hameid MK; El-Nassan HB; El-Khouly EA
Med Chem; 2019; 15(8):873-882. PubMed ID: 30961505
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]