These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
129 related articles for article (PubMed ID: 2605239)
1. Isotopically labeled chlorobenzenes as probes for the mechanism of cytochrome P-450 catalyzed aromatic hydroxylation. Korzekwa KR; Swinney DC; Trager WF Biochemistry; 1989 Nov; 28(23):9019-27. PubMed ID: 2605239 [TBL] [Abstract][Full Text] [Related]
2. Intramolecular isotope effects associated with meta-hydroxylation of biphenyl catalyzed by cytochrome P-450. Swinney DC; Howald WN; Trager WF Biochem Biophys Res Commun; 1984 Feb; 118(3):867-72. PubMed ID: 6704111 [TBL] [Abstract][Full Text] [Related]
3. Substrate probes for the mechanism of aromatic hydroxylation catalyzed by cytochrome P-450: selectively deuterated analogues of warfarin. Bush ED; Trager WF J Med Chem; 1985 Aug; 28(8):992-6. PubMed ID: 4020838 [TBL] [Abstract][Full Text] [Related]
4. A proton-shuttle mechanism mediated by the porphyrin in benzene hydroxylation by cytochrome p450 enzymes. de Visser SP; Shaik S J Am Chem Soc; 2003 Jun; 125(24):7413-24. PubMed ID: 12797816 [TBL] [Abstract][Full Text] [Related]
5. Prochiral selectivity and intramolecular isotope effects in the cytochrome P-450 catalyzed omega-hydroxylation of cumene. Sugiyama K; Trager WF Biochemistry; 1986 Nov; 25(23):7336-43. PubMed ID: 3801417 [TBL] [Abstract][Full Text] [Related]
6. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation. Kim KH; Isin EM; Yun CH; Kim DH; Guengerich FP FEBS J; 2006 May; 273(10):2223-31. PubMed ID: 16649998 [TBL] [Abstract][Full Text] [Related]
7. Cytochrome P450-catalyzed hydroxylation of hydrocarbons: kinetic deuterium isotope effects for the hydroxylation of an ultrafast radical clock. Atkinson JK; Hollenberg PF; Ingold KU; Johnson CC; Le Tadic MH; Newcomb M; Putt DA Biochemistry; 1994 Sep; 33(35):10630-7. PubMed ID: 8075063 [TBL] [Abstract][Full Text] [Related]
8. Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450 catalyzed hydroxylation of octane is isozyme independent. Jones JP; Rettie AE; Trager WF J Med Chem; 1990 Apr; 33(4):1242-6. PubMed ID: 2319565 [TBL] [Abstract][Full Text] [Related]
9. Liver microsomal electron transport systems. III. The involvement of cytochrome b5 in the NADPH-supported cytochrome P-450-dependent hydroxylation of chlorobenzene. Lu AY; Levin W; Selander H; Jerina DM Biochem Biophys Res Commun; 1974 Dec; 61(4):1348-55. PubMed ID: 4156173 [No Abstract] [Full Text] [Related]
10. Low kinetic hydrogen isotope effects in the dehydrogenation of 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester (nifedipine) by cytochrome P-450 enzymes are consistent with an electron/proton/electron transfer mechanism. Guengerich FP Chem Res Toxicol; 1990; 3(1):21-6. PubMed ID: 2131820 [TBL] [Abstract][Full Text] [Related]
11. Mechanism of microsomal metabolism of benzene to phenol. Hinson JA; Freeman JP; Potter DW; Mitchum RK; Evans FE Mol Pharmacol; 1985 May; 27(5):574-7. PubMed ID: 3990679 [TBL] [Abstract][Full Text] [Related]
12. Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect. Iyer KR; Jones JP; Darbyshire JF; Trager WF Biochemistry; 1997 Jun; 36(23):7136-43. PubMed ID: 9188713 [TBL] [Abstract][Full Text] [Related]
13. Hydroxylation of specifically deuterated limonene enantiomers by cytochrome p450 limonene-6-hydroxylase reveals the mechanism of multiple product formation. Wüst M; Croteau RB Biochemistry; 2002 Feb; 41(6):1820-7. PubMed ID: 11827526 [TBL] [Abstract][Full Text] [Related]