BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 26056430)

  • 1. p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo.
    Stamper BD; Garcia ML; Nguyen DQ; Beyer RP; Bammler TK; Farin FM; Kavanagh TJ; Nelson SD
    Gene Regul Syst Bio; 2015; 9():1-14. PubMed ID: 26056430
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells.
    Stamper BD; Bammler TK; Beyer RP; Farin FM; Nelson SD
    Toxicol Sci; 2010 Jul; 116(1):164-73. PubMed ID: 20363829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.
    Rashed MS; Myers TG; Nelson SD
    Drug Metab Dispos; 1990; 18(5):765-70. PubMed ID: 1981734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver.
    Hadi M; Dragovic S; van Swelm R; Herpers B; van de Water B; Russel FG; Commandeur JN; Groothuis GM
    Arch Toxicol; 2013 Jan; 87(1):155-65. PubMed ID: 22914986
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol.
    Fountoulakis M; Berndt P; Boelsterli UA; Crameri F; Winter M; Albertini S; Suter L
    Electrophoresis; 2000 Jun; 21(11):2148-61. PubMed ID: 10892726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of glutathione conjugates of reactive metabolites of 3'-hydroxyacetanilide, a nonhepatotoxic positional isomer of acetaminophen.
    Rashed MS; Nelson SD
    Chem Res Toxicol; 1989; 2(1):41-5. PubMed ID: 2519230
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Use of a systems model of drug-induced liver injury (DILIsym(®)) to elucidate the mechanistic differences between acetaminophen and its less-toxic isomer, AMAP, in mice.
    Howell BA; Siler SQ; Watkins PB
    Toxicol Lett; 2014 Apr; 226(2):163-72. PubMed ID: 24560604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative Toxicity and Metabolism of N-Acyl Homologues of Acetaminophen and Its Isomer 3'-Hydroxyacetanilide.
    Koen YM; Liu K; Shinogle H; Williams TD; Hanzlik RP
    Chem Res Toxicol; 2016 Nov; 29(11):1857-1864. PubMed ID: 27680534
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell culture model for acetaminophen-induced hepatocyte death in vivo.
    Pierce RH; Franklin CC; Campbell JS; Tonge RP; Chen W; Fausto N; Nelson SD; Bruschi SA
    Biochem Pharmacol; 2002 Aug; 64(3):413-24. PubMed ID: 12147292
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen.
    Lee YS; Wan J; Kim BJ; Bae MA; Song BJ
    J Pharmacol Exp Ther; 2006 Apr; 317(1):202-8. PubMed ID: 16330492
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inactivation of glyceraldehyde-3-phosphate dehydrogenase by a reactive metabolite of acetaminophen and mass spectral characterization of an arylated active site peptide.
    Dietze EC; Schäfer A; Omichinski JG; Nelson SD
    Chem Res Toxicol; 1997 Oct; 10(10):1097-103. PubMed ID: 9348431
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative cytotoxic effects of acetaminophen (N-acetyl-p-aminophenol), a non-hepatotoxic regioisomer acetyl-m-aminophenol and their postulated reactive hydroquinone and quinone metabolites in monolayer cultures of mouse hepatocytes.
    Holme JA; Hongslo JK; Bjørge C; Nelson SD
    Biochem Pharmacol; 1991 Aug; 42(5):1137-42. PubMed ID: 1872898
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oral exposure to drugs with immune-adjuvant potential induces hypersensitivity responses to the reporter antigen TNP-OVA.
    Kwast LM; Fiechter D; Hassing I; Bleumink R; Boon L; Ludwig IS; Pieters RH
    Toxicol Sci; 2011 Jun; 121(2):312-9. PubMed ID: 21402728
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies.
    Rao MS; Van Vleet TR; Ciurlionis R; Buck WR; Mittelstadt SW; Blomme EAG; Liguori MJ
    Front Genet; 2018; 9():636. PubMed ID: 30723492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.
    Kyriakides M; Maitre L; Stamper BD; Mohar I; Kavanagh TJ; Foster J; Wilson ID; Holmes E; Nelson SD; Coen M
    Arch Toxicol; 2016 Dec; 90(12):3073-3085. PubMed ID: 26746206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigations of the N-hydroxylation of 3'-hydroxyacetanilide, a non-hepatotoxic positional isomer of acetaminophen.
    Rashed MS; Streeter AJ; Nelson SD
    Drug Metab Dispos; 1989; 17(4):355-9. PubMed ID: 2571471
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploring Chemical Routes Relevant to the Toxicity of Paracetamol and Its meta-Analogue at a Molecular Level.
    Castañeda-Arriaga R; Galano A
    Chem Res Toxicol; 2017 Jun; 30(6):1286-1301. PubMed ID: 28475314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential gene expression analysis of a known hepatotoxin, N-acetyl-p-amino-phenol (APAP) as compared to its non-toxic analog, N-acetyl-m-amino-phenol (AMAP) in mouse liver.
    Priyadarsiny P; Khattar SK; Malik R; Udupa V; Seshaiah A; Rahman S; Shingatgeri VM; Bora RS; Saini KS
    J Toxicol Sci; 2008 May; 33(2):163-73. PubMed ID: 18544908
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of acetaminophen on hepatic gene expression in mice.
    Jeong SY; Lim JS; Park HJ; Cho JW; Rana SV; Yoon S
    Physiol Chem Phys Med NMR; 2006; 38(2):77-83. PubMed ID: 18472468
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acetaminophen analog N-acetyl-m-aminophenol, but not its reactive metabolite, N-acetyl-p-benzoquinone imine induces CYP3A activity via inhibition of protein degradation.
    Santoh M; Sanoh S; Ohtsuki Y; Ejiri Y; Kotake Y; Ohta S
    Biochem Biophys Res Commun; 2017 May; 486(3):639-644. PubMed ID: 28341123
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.